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Drug-target binding affinity prediction is a fundamental task for drug discovery. It has been extensively explored in literature and promising results are reported. However, in this paper, we demonstrate that the results may be misleading…

Machine Learning · Computer Science 2025-04-15 Chenbin Zhang , Zhiqiang Hu , Chuchu Jiang , Wen Chen , Jie Xu , Shaoting Zhang

Predictions from machine learning algorithms can vary across random seeds, inducing instability in downstream debiased machine learning estimators. We formalize random seed stability via a concentration condition and prove that subbagging…

Methodology · Statistics 2026-04-21 Nicholas Williams , Alejandro Schuler

We study the detection problem of finding planted solutions in random instances of flat satisfiability problems, a generalization of boolean satisfiability formulas. We describe the properties of random instances of flat satisfiability, as…

Statistics Theory · Mathematics 2019-03-07 Quentin Berthet , Jordan S. Ellenberg

In any given machine learning problem, there may be many models that could explain the data almost equally well. However, most learning algorithms return only one of these models, leaving practitioners with no practical way to explore…

Machine Learning · Computer Science 2022-10-27 Rui Xin , Chudi Zhong , Zhi Chen , Takuya Takagi , Margo Seltzer , Cynthia Rudin

Sensor selection is critical for state estimation, control and monitoring of nonlinear processes. However, evaluating the performance of each possible combination of $m$ out of $n$ sensors is impractical unless $m$ and $n$ are small. In…

Systems and Control · Electrical Eng. & Systems 2022-08-02 Siyu Liu , Xunyuan Yin , Zhichao Pan , Jinfeng Liu

Sensitivity analysis measures the influence of a Bayesian network's parameters on a quantity of interest defined by the network, such as the probability of a variable taking a specific value. In particular, the so-called sensitivity value…

Artificial Intelligence · Computer Science 2022-06-20 Rafael Ballester-Ripoll , Manuele Leonelli

Multispectral images acquired by satellites are used to study phenomena on the Earth's surface. Unsupervised classification techniques analyze multispectral image content without considering prior knowledge of the observed terrain; this is…

Computer Vision and Pattern Recognition · Computer Science 2019-11-12 Wuilian Torres , Antonio Rueda-Toicen

Understanding the dietary preferences of ancient societies and their evolution across periods and regions is crucial for revealing human-environment interactions. Seeds, as important archaeological artifacts, represent a fundamental subject…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Rui Xing , Runmin Cong , Yingying Wu , Can Wang , Zhongming Tang , Fen Wang , Hao Wu , Sam Kwong

We investigate an application in the automatic tuning of computer codes, an area of research that has come to prominence alongside the recent rise of distributed scientific processing and heterogeneity in high-performance computing…

Applications · Statistics 2013-04-17 Robert B. Gramacy , Matt Taddy , Stefan M. Wild

Interactive image segmentation algorithms rely on the user to provide annotations as the guidance. When the task of interactive segmentation is performed on a small touchscreen device, the requirement of providing precise annotations could…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Ding-Jie Chen , Hwann-Tzong Chen , Long-Wen Chang

Deep learning has produced big advances in artificial intelligence, but trained neural networks often reflect and amplify bias in their training data, and thus produce unfair predictions. We propose a novel measure of individual fairness,…

Artificial Intelligence · Computer Science 2020-09-30 Krystal Maughan , Joseph P. Near

Deep Neural Networks (DNNs) have recently shown state of the art performance on semantic segmentation tasks, however, they still suffer from problems of poor boundary localization and spatial fragmented predictions. The difficulties lie in…

Computer Vision and Pattern Recognition · Computer Science 2018-10-29 Peng Jiang , Fanglin Gu , Yunhai Wang , Changhe Tu , Baoquan Chen

Tree kernels have been proposed to be used in many areas as the automatic learning of natural language applications. In this paper, we propose a new linear time algorithm based on the concept of weighted tree automata for SubTree kernel…

Computation and Language · Computer Science 2023-02-03 Ludovic Mignot , Faissal Ouardi , Djelloul Ziadi

Plant phenotyping refers to a quantitative description of the plants properties, however in image-based phenotyping analysis, our focus is primarily on the plants anatomical, ontogenetical and physiological properties.This technique…

Computer Vision and Pattern Recognition · Computer Science 2022-10-25 Petros N. Tamvakis , Chairi Kiourt , Alexandra D. Solomou , George Ioannakis , Nestoras C. Tsirliganis

Submodular functions allow to model many real-world optimisation problems. This paper introduces approaches for computing diverse sets of high quality solutions for submodular optimisation problems. We first present diversifying greedy…

Artificial Intelligence · Computer Science 2020-10-23 Aneta Neumann , Jakob Bossek , Frank Neumann

We study the task of selecting $k$ nodes, in a social network of size $n$, to seed a diffusion with maximum expected spread size, under the independent cascade model with cascade probability $p$. Most of the previous work on this problem…

Social and Information Networks · Computer Science 2022-05-24 Dean Eckles , Hossein Esfandiari , Elchanan Mossel , M. Amin Rahimian

Convolutional neural networks trained using manually generated labels are commonly used for semantic or instance segmentation. In precision agriculture, automated flower detection methods use supervised models and post-processing techniques…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Abubakar Siddique , Amy Tabb , Henry Medeiros

This paper defines a generalized column subset selection problem which is concerned with the selection of a few columns from a source matrix A that best approximate the span of a target matrix B. The paper then proposes a fast greedy…

Data Structures and Algorithms · Computer Science 2013-12-25 Ahmed K. Farahat , Ali Ghodsi , Mohamed S. Kamel

With the need to feed a growing world population, the efficiency of crop production is of paramount importance. To support breeding and field management, various characteristics of the plant phenotype need to be measured -- a time-consuming…

Data selection seeks to identify a compact yet informative subset from large-scale training corpora, balancing sample quality against collection diversity. We formulate this problem as a Weighted Independent Set (WIS) on a similarity graph,…

Machine Learning · Computer Science 2026-05-21 Yuan Zhang , Lifeng Guo , Junwen Pan , Wenzhao Zheng , Wen Zhou , Kuan Cheng , Kurt Keutzer , Shanghang Zhang
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