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We present a new experimental-computational technology of inferring network models that predict the response of cells to perturbations and that may be useful in the design of combinatorial therapy against cancer. The experiments are…

Unsupervised neural networks, such as restricted Boltzmann machines (RBMs) and deep belief networks (DBNs), are powerful tools for feature selection and pattern recognition tasks. We demonstrate that overfitting occurs in such models just…

Machine Learning · Computer Science 2017-02-20 Baiyang Wang , Diego Klabjan

Recent advances in Large Language Models (LLMs) have intensified the debate surrounding the fundamental nature of their reasoning capabilities. While achieving high performance on benchmarks such as GPQA and MMLU, these models exhibit…

Artificial Intelligence · Computer Science 2025-01-24 Santosh Kumar Radha , Oktay Goktas

We present an efficient parametric model checking (PMC) technique for the analysis of software performability, i.e., of the performance and dependability properties of software systems. The new PMC technique works by automatically…

Logic in Computer Science · Computer Science 2022-10-25 Xinwei Fang , Radu Calinescu , Simos Gerasimou , Faisal Alhwikem

This proof of concept (PoC) assesses the ability of machine learning (ML) classifiers to predict the presence of a stenosis in a three vessel arterial system consisting of the abdominal aorta bifurcating into the two common iliacs. A…

Machine Learning · Computer Science 2021-08-31 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Unmasking the decision-making process of machine learning models is essential for implementing diagnostic support systems in clinical practice. Here, we demonstrate that adversarially trained models can significantly enhance the usability…

Despite huge successes on a wide range of tasks, neural networks are known to sometimes struggle to generalise to unseen data. Many approaches have been proposed over the years to promote the generalisation ability of neural networks,…

Machine Learning · Computer Science 2026-02-02 Christiaan P. Opperman , Anna S. Bosman , Katherine M. Malan

End-to-end deep neural networks have achieved remarkable success across various domains but are often criticized for their lack of interpretability. While post hoc explanation methods attempt to address this issue, they often fail to…

Machine Learning · Computer Science 2025-01-22 Weixin Chen , Simon Yu , Huajie Shao , Lui Sha , Han Zhao

In this paper, we study networks of positive linear systems subject to time-invariant and random uncertainties. We present linear matrix inequalities for checking the stability of the whole network around the origin with prescribed…

Optimization and Control · Mathematics 2016-11-09 Masaki Ogura , Victor M. Preciado

We study algorithmic problems in multi-stage open shop processing systems that are centered around reachability and deadlock detection questions. We characterize safe and unsafe system states. We show that it is easy to recognize system…

Data Structures and Algorithms · Computer Science 2011-02-16 Christian Eggermont , Alexander Schrijver , Gerhard J. Woeginger

Probabilistic circuits (PCs) are a class of tractable probabilistic models, which admit efficient inference routines depending on their structural properties. In this paper, we introduce md-vtrees, a novel structural formulation of…

Artificial Intelligence · Computer Science 2023-04-18 Benjie Wang , Marta Kwiatkowska

Deep neural networks have proven remarkably effective at solving many classification problems, but have been criticized recently for two major weaknesses: the reasons behind their predictions are uninterpretable, and the predictions…

Machine Learning · Computer Science 2017-11-28 Andrew Slavin Ross , Finale Doshi-Velez

Machine learning, particularly convolutional neural networks (CNNs), has shown promise in medical image analysis, especially for thoracic disease detection using chest X-ray images. In this study, we evaluate various CNN architectures,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tejas Mirthipati

Neural networks are among the most accurate supervised learning methods in use today. However, their opacity makes them difficult to trust in critical applications, especially when conditions in training may differ from those in practice.…

Machine Learning · Computer Science 2018-10-03 Andrew Slavin Ross

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

Deep learning methods for ophthalmic diagnosis have shown considerable success in tasks like segmentation and classification. However, their widespread application is limited due to the models being opaque and vulnerable to making a wrong…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Amitojdeep Singh , Sourya Sengupta , Mohammed Abdul Rasheed , Varadharajan Jayakumar , Vasudevan Lakshminarayanan

In this paper the application of uncertainty modeling to convolutional neural networks is evaluated. A novel method for adjusting the network's predictions based on uncertainty information is introduced. This allows the network to be either…

Computer Vision and Pattern Recognition · Computer Science 2016-12-23 Rene Grzeszick , Sebastian Sudholt , Gernot A. Fink

For the diagnostic inference under uncertainty Bayesian networks are investigated. The method is based on an adequate uniform representation of the necessary knowledge. This includes both generic and experience-based specific knowledge,…

Artificial Intelligence · Computer Science 2022-10-11 Sebastian Flügge , Sandra Zimmer , Uwe Petersohn

Multicore parallel programming has some very difficult problems such as deadlocks during synchronizations and race conditions brought by concurrency. Added to the difficulty is the lack of a simple, well-accepted computing model for…

Programming Languages · Computer Science 2010-12-09 Yibing Wang

This work addresses whether a reaction network, taken with mass-action kinetics, is multistationary, that is, admits more than one positive steady state in some stoichiometric compatibility class. We build on previous work on the effect…

Molecular Networks · Quantitative Biology 2019-08-27 AmirHosein Sadeghimanesh , Elisenda Feliu
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