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Synaptic delays play a crucial role in biological neuronal networks, where their modulation has been observed in mammalian learning processes. In the realm of neuromorphic computing, although spiking neural networks (SNNs) aim to emulate…

Neural and Evolutionary Computing · Computer Science 2025-06-19 Marissa Dominijanni , Alexander Ororbia , Kenneth W. Regan

We studied LSMO/Alq3/AlOx/Co molecular spin valves in view of their use as synapses in neuromorphic computing. In neuromorphic computing, the learning ability is embodied in specific changes of the synaptic weight. In this perspective, the…

Emerging Technologies · Computer Science 2019-03-26 Alberto Riminucci , Robert Legenstein

Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

In neuromorphic computing, artificial synapses provide a multi-weight conductance state that is set based on inputs from neurons, analogous to the brain. Additional properties of the synapse beyond multiple weights can be needed, and can…

A major obstacle to understanding neural coding and computation is the fact that experimental recordings typically sample only a small fraction of the neurons in a circuit. Measured neural properties are skewed by interactions between…

Neurons and Cognition · Quantitative Biology 2025-04-01 Braden A. W. Brinkman , Fred Rieke , Eric Shea-Brown , Michael A. Buice

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

Predictive coding (PC) is a general theory of cortical function. The local, gradient-based learning rules found in one kind of PC model have recently been shown to closely approximate backpropagation. This finding suggests that this…

Neural and Evolutionary Computing · Computer Science 2021-12-09 Nick Alonso , Emre Neftci

Biological agents do not have infinite resources to learn new things. For this reason, a central aspect of human learning is the ability to recycle previously acquired knowledge in a way that allows for faster, less resource-intensive…

Artificial Intelligence · Computer Science 2022-05-27 Christian David Márton , Léo Gagnon , Guillaume Lajoie , Kanaka Rajan

Synaptic plasticity, the dynamic tuning of signal transmission strength between neurons, serves as a fundamental basis for memory and learning in biological organisms. This adaptive nature of synapses is considered one of the key features…

Mesoscale and Nanoscale Physics · Physics 2024-11-11 Yechan Noh , Alex Smolyanitsky

The brain processes information through many layers of neurons. This deep architecture is representationally powerful, but it complicates learning by making it hard to identify the responsible neurons when a mistake is made. In machine…

Neurons and Cognition · Quantitative Biology 2014-11-04 Timothy P. Lillicrap , Daniel Cownden , Douglas B. Tweed , Colin J. Akerman

Maintaining the ability to fire sparsely is crucial for information encoding in neural networks. Additionally, spiking homeostasis is vital for spiking neural networks with changing numbers of weights and neurons. We discuss a range of…

Neural and Evolutionary Computing · Computer Science 2019-10-02 Katarzyna Kozdon , Peter Bentley

We study a novel architecture and training procedure for locomotion tasks. A high-frequency, low-level "spinal" network with access to proprioceptive sensors learns sensorimotor primitives by training on simple tasks. This pre-trained…

Robotics · Computer Science 2016-10-18 Nicolas Heess , Greg Wayne , Yuval Tassa , Timothy Lillicrap , Martin Riedmiller , David Silver

In complex systems, we often observe complex global behavior emerge from a collection of agents interacting with each other in their environment, with each individual agent acting only on locally available information, without knowing the…

Neural and Evolutionary Computing · Computer Science 2021-09-30 Yujin Tang , David Ha

Neurotransmitter receptor molecules, concentrated in postsynaptic domains along with scaffold and a number of other molecules, are key regulators of signal transmission across synapses. Employing experiment and theory, we develop a…

Neurons and Cognition · Quantitative Biology 2015-05-20 Christoph A. Haselwandter , Martino Calamai , Mehran Kardar , Antoine Triller , Rava Azeredo da Silveira

Neuromodulation is central to the adaptation and robustness of animal nervous systems. This paper explores the classical paradigm of indirect adaptive control to design neuromodulatory controllers in conductance-based neuronal models. The…

Systems and Control · Electrical Eng. & Systems 2022-11-03 Raphael Schmetterling , Thiago Burghi , Rodolphe Sepulchre

Deep Neural Networks (DNNs) rely on inherent fluctuations in their internal parameters (weights and biases) to effectively navigate the complex optimization landscape and achieve robust performance. While these fluctuations are recognized…

Machine Learning · Computer Science 2025-11-14 Darsh Pareek , Umesh Kumar , Ruthu Rao , Ravi Janjam

Spiking neural networks (SNNs) represent a promising approach in machine learning, combining the hierarchical learning capabilities of deep neural networks with the energy efficiency of spike-based computations. Traditional end-to-end…

Neural and Evolutionary Computing · Computer Science 2024-11-12 Ruyin Wan , Qian Zhang , George Em Karniadakis

The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…

Neurons and Cognition · Quantitative Biology 2020-04-28 Alan Eric Akil , Robert Rosenbaum , Krešimir Josić

Synaptic, dendritic and single-cell kinetics generate significant time delays that shape the dynamics of large networks of spiking neurons. Previous work has shown that such effective delays can be taken into account with a rate model…

Neurons and Cognition · Quantitative Biology 2014-01-31 Alex Roxin , Ernest Montbrio