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Cancer progression and monotonic accumulation models were developed to discover dependencies in the irreversible acquisition of binary traits from cross-sectional data. They have been used in computational oncology and virology but also in…

Populations and Evolution · Quantitative Biology 2025-05-12 Ramon Diaz-Uriarte , Iain G. Johnston

Recently it has been proved that simple GP systems can efficiently evolve the conjunction of $n$ variables if they are equipped with the minimal required components. In this paper, we make a considerable step forward by analysing the…

Neural and Evolutionary Computing · Computer Science 2019-05-03 Benjamin Doerr , Andrei Lissovoi , Pietro S. Oliveto

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

Molecular Networks · Quantitative Biology 2014-04-23 Yi Ming Zou

The study of a machine learning problem is in many ways is difficult to separate from the study of the loss function being used. One avenue of inquiry has been to look at these loss functions in terms of their properties as scoring rules…

Machine Learning · Computer Science 2022-09-02 Zac Cranko , Robert C. Williamson , Richard Nock

Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular nodes, each being associated to a Boolean variable and a…

Discrete Mathematics · Computer Science 2025-06-24 José E. R. Cury , Patrícia Tenera Roxo , Vasco Manquinho , Claudine Chaouiya , Pedro T. Monteiro

We found that models of evolving random networks exhibit dynamic scaling similar to scaling of growing surfaces. It is demonstrated by numerical simulations of two variants of the model in which nodes are added as well as removed [Phys.…

Statistical Mechanics · Physics 2009-11-07 Miroslav Kotrla , Frantisek Slanina , Jakub Steiner

We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule, and which is also robust against noise. Robustness is quantified as the…

Biological Physics · Physics 2010-12-02 Christoph Schmal , Tiago P. Peixoto , Barbara Drossel

The abundance of models of complex networks and the current insufficient validation standards make it difficult to judge which models are strongly supported by data and which are not. We focus here on likelihood maximization methods for…

Physics and Society · Physics 2014-03-26 Matus Medo

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

We are interested in the cycles obtained by slicing at all heights random Boltzmann triangulations with a simple boundary. We establish a functional invariance principle for the lengths of these cycles, appropriately rescaled, as the size…

Probability · Mathematics 2018-02-19 Jean Bertoin , Nicolas Curien , Igor Kortchemski

From genomes and ecosystems to bureaucracies and cities, the growth of complex systems occurs by adding new types of functions and expanding existing ones. We present a simple generative model that generalizes the Yule-Simon process by…

We study a class of growth algorithms for directed graphs that are candidate models for the evolution of genetic regulatory networks. The algorithms involve partial duplication of nodes and their links, together with innovation of new…

Molecular Networks · Quantitative Biology 2007-05-23 D. V. Foster , S. A. Kauffman , J. E. S. Socolar

Parametric high-dimensional regression analysis requires the usage of regularization terms to get interpretable models. The respective estimators can be regarded as regularized M-functionals which are naturally highly nonlinear. We study…

Statistics Theory · Mathematics 2019-09-04 Tino Werner

In this paper we investigate the growth rate of the number of all possible paths in graphs with respect to their length in an exact analytical way. Apart from the typical rates of growth, i.e. exponential or polynomial, we identify…

Dynamical Systems · Mathematics 2007-05-23 Vasileios Basios , Gian-Luigi Forti , Gregoire Nicolis

The organizational development of growing random networks is investigated. These growing networks are built by adding nodes successively and linking each to an earlier node of degree k with attachment probability A_k. When A_k grows slower…

Statistical Mechanics · Physics 2009-10-31 P. L. Krapivsky , S. Redner

We investigate the expressive power of neural networks from the point of view of descriptive complexity. We study neural networks that use floating-point numbers and piecewise polynomial activation functions from two perspectives: 1) the…

Computational Complexity · Computer Science 2025-05-12 Veeti Ahvonen , Damian Heiman , Antti Kuusisto

We consider a branching particle system where each particle moves as an independent Brownian motion and breeds at a rate proportional to its distance from the origin raised to the power $p$, for $p\in[0,2)$. The asymptotic behaviour of the…

Probability · Mathematics 2014-02-24 Julien Berestycki , Éric Brunet , John W. Harris , Simon C. Harris , Matthew I. Roberts

In a recent paper, Krapivsky and Redner (Phys. Rev. E, 71 (2005) 036118) proposed a new growing network model with new nodes being attached to a randomly selected node, as well to all ancestors of the target node. The model leads to a…

Physics and Society · Physics 2007-05-23 Sergi Valverde , Ricard V. Sole

The study of causal structure in complex systems has gained increasing attention, with many recent studies exploring causal networks that capture cause-effect relationships across diverse fields. Despite increasing empirical evidence…

Physics and Society · Physics 2025-02-26 Jiazhen Liu , Kunal Tamang , Dashun Wang , Chaoming Song
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