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Ultametrics are an important class of distances used in applications such as phylogenetics, clustering and classification theory. Ultrametrics are essentially distances that can be represented by an edge-weighted rooted tree so that all of…

Combinatorics · Mathematics 2026-02-13 Katharina T. Huber , Vincent Moulton , Guillaume E. Scholz

This paper introduces constNJ, the first algorithm for phylogenetic reconstruction of sets of trees with constrained pairwise rooted subtree-prune regraft (rSPR) distance. We are motivated by the problem of constructing sets of trees which…

Populations and Evolution · Quantitative Biology 2009-09-30 Frederick A. Matsen

A central theme in phylogenetics is the reconstruction and analysis of evolutionary trees from a given set of data. To determine the optimal search methods for reconstructing trees, it is crucial to understand the size and structure of the…

Populations and Evolution · Quantitative Biology 2016-08-15 Jamie V. de Jong , Jeanette C McLeod , Mike Steel

Phylogenetic trees are leaf-labelled trees, where the leaves correspond to extant species (taxa), and the internal vertices represent ancestral species. The evolutionary history of a set of species can be explained by more than one…

Data Structures and Algorithms · Computer Science 2016-09-07 Asish Mukhopadhyay , Puspal Bhabak

Two genes are xenologs in the sense of Fitch if they are separated by at least one horizontal gene transfer event. Horizonal gene transfer is asymmetric in the sense that the transferred copy is distinguished from the one that remains…

Discrete Mathematics · Computer Science 2018-02-13 Manuela Geiß , John Anders , Peter F. Stadler , Nicolas Wieseke , Marc Hellmuth

The popular neighbor-joining (NJ) algorithm used in phylogenetics is a greedy algorithm for finding the balanced minimum evolution (BME) tree associated to a dissimilarity map. From this point of view, NJ is ``optimal'' when the algorithm…

Quantitative Methods · Quantitative Biology 2007-10-29 Kord Eickmeyer , Peter Huggins , Lior Pachter , Ruriko Yoshida

Due to hybridization events in evolution, studying two different genes of a set of species may yield two related but different phylogenetic trees for the set of species. In this case, we want to measure the dissimilarity of the two trees.…

Data Structures and Algorithms · Computer Science 2017-07-28 Zhi-Zhong Chen , Eita Machida , Lusheng Wang

Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

Populations and Evolution · Quantitative Biology 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

We present a novel method of stacking decision trees by projection into an ordered time split out-of-fold (OOF) one nearest neighbor (1NN) space. The predictions of these one nearest neighbors are combined through a linear model. This…

Machine Learning · Computer Science 2021-03-31 Michael Kim

We introduce a semiparametric approach to neighbor-based classification. We build off the recently proposed Boundary Trees algorithm by Mathy et al.(2015) which enables fast neighbor-based classification, regression and retrieval in large…

Machine Learning · Computer Science 2018-10-29 Tharindu Adikari , Stark C. Draper

A metric phylogenetic tree relating a collection of taxa induces weighted rooted triples and weighted quartets for all subsets of three and four taxa, respectively. New intertaxon distances are defined that can be calculated from these…

Populations and Evolution · Quantitative Biology 2020-02-12 Samaneh Yourdkhani , John A. Rhodes

The subtree prune-and-regraft (SPR) distance metric is a fundamental way of comparing evolutionary trees. It has wide-ranging applications, such as to study lateral genetic transfer, viral recombination, and Markov chain Monte Carlo…

Discrete Mathematics · Computer Science 2016-11-09 Chris Whidden , Frederick A. Matsen

Given an undirected, weighted graph, the minimum spanning tree (MST) is a tree that connects all of the vertices of the graph with minimum sum of edge weights. In real world applications, network designers often seek to quickly find a…

Data Structures and Algorithms · Computer Science 2023-01-02 David A. Bader , Paul Burkhardt

The subtree prune-and-regraft (SPR) distance metric is a fundamental way of comparing evolutionary trees. It has wide-ranging applications, such as to study lateral genetic transfer, viral recombination, and Markov chain Monte Carlo…

Data Structures and Algorithms · Computer Science 2017-11-07 Chris Whidden , Frederick A. Matsen

The reconstruction of phylogenetic networks is an important but challenging problem in phylogenetics and genome evolution, as the space of phylogenetic networks is vast and cannot be sampled well. One approach to the problem is to solve the…

Populations and Evolution · Quantitative Biology 2023-04-14 Louxin Zhang , Niloufar Abhari , Caroline Colijn , Yufeng Wu

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

Populations and Evolution · Quantitative Biology 2018-12-21 Sebastien Roch

Edit distances between merge trees of scalar fields have many applications in scientific visualization, such as ensemble analysis, feature tracking or symmetry detection. In this paper, we propose branch mappings, a novel approach to the…

Computational Geometry · Computer Science 2022-08-12 Florian Wetzels , Heike Leitte , Christoph Garth

Previously in 2014, we proposed the Nearest Descent (ND) method, capable of generating an efficient Graph, called the in-tree (IT). Due to some beautiful and effective features, this IT structure proves well suited for data clustering.…

Machine Learning · Statistics 2016-03-07 Teng Qiu , Yongjie Li

Graph Neural Networks (GNNs) have proven to be powerful in many graph-based applications. However, they fail to generalize well under heterophilic setups, where neighbor nodes have different labels. To address this challenge, we employ a…

Machine Learning · Computer Science 2023-04-13 Yoonhyuk Choi , Jiho Choi , Taewook Ko , Chong-Kwon Kim

The {\em edit distance} between two ordered trees with vertex labels is the minimum cost of transforming one tree into the other by a sequence of elementary operations consisting of deleting and relabeling existing nodes, as well as…

Data Structures and Algorithms · Computer Science 2010-12-01 Erik D. Demaine , Shay Mozes , Benjamin Rossman , Oren Weimann