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Multicellular organisms comprise a diverse collection of stable tissues built from different cell types. It remains unclear how large numbers of interacting cells can precisely coordinate their gene expression during tissue…

Biological Physics · Physics 2022-10-31 Matthew Smart , Anton Zilman

The activity of biological cells is primarily based on chemical reactions and typically modeled as a reaction-diffusion system. Cells are, however, highly crowded with macromolecules, including a variety of molecular machines such as…

Biological Physics · Physics 2018-11-02 Yuichi Togashi

Multicell joint processing has been proven to be very efficient in overcoming the interference-limited nature of the cellular paradigm. However, for reasons of practical implementation global multicell joint decoding is not feasible and…

Information Theory · Computer Science 2011-11-22 Symeon Chatzinotas , Bjorn Ottersten

Nanoparticle agglomeration in a quiescent fluid is simulated by solving the Langevin equations of motion of a set of interacting monomers in the continuum regime. Monomers interact via a radial, rapidly decaying intermonomer potential. The…

Statistical Mechanics · Physics 2010-08-13 Lorenzo Isella , Yannis Drossinos

This paper continues our survey about the mean-field derivation of the two-dimensional signal-dependent Keller-Segel system studied in [1]. Therefore, we consider the same system of moderately interacting particles as before. The difference…

Probability · Mathematics 2026-05-18 Lukas Bol , Li Chen

A novel theory for cell differentiation is proposed, based on simulations with interacting artificial cells which have metabolic networks within, and divide into two when the final product is accumulated. Results of simulations with coupled…

adap-org · Physics 2015-06-30 Kunihiko Kaneko , Tetsuya Yomo

We propose a thermodynamic multi-state spin model in order to describe equilibrial behavior of a society. Our model is inspired by the Axelrod model used in social network studies. In the framework of the statistical mechanics language, we…

Physics and Society · Physics 2015-01-09 Jozef Genzor , Vladimir Buzek , Andrej Gendiar

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

Analysis of PDEs · Mathematics 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

In a complex system, the interactions between individual agents often lead to emergent collective behavior like spontaneous synchronization, swarming, and pattern formation. The topology of the network of interactions can have a dramatic…

Adaptation and Self-Organizing Systems · Physics 2022-07-25 Mark J Panaggio , Maria-Veronica Ciocanel , Lauren Lazarus , Chad M Topaz , Bin Xu

We review the methods based on expectation value coupled cluster formalism - a common framework for the derivation of properties: the ground-state average value of an observable, cumulants of the second-order reduced density matrices,…

Chemical Physics · Physics 2021-11-15 Aleksandra M. Tucholska , Robert Moszynski

A molecular communication channel is determined by the received signal. Received signal models form the basis for studies focused on modulation, receiver design, capacity, and coding depend on the received signal models. Therefore, it is…

Emerging Technologies · Computer Science 2016-11-21 H. Birkan Yilmaz , Changmin Lee , Yae Jee Cho , Chan-Byoung Chae

Transformers are extremely successful machine learning models whose mathematical properties remain poorly understood. Here, we rigorously characterize the behavior of transformers with hardmax self-attention and normalization sublayers as…

Computation and Language · Computer Science 2026-05-14 Albert Alcalde , Giovanni Fantuzzi , Enrique Zuazua

Development in multi-cellular organisms is marked by a high degree of spatial organization of the cells attaining distinct fates in the embryo. We show that receptor-ligand interaction between cells in close physical proximity adaptively…

Tissues and Organs · Quantitative Biology 2021-06-30 Chandrashekar Kuyyamudi , Shakti N. Menon , Sitabhra Sinha

Segregation of different cell types is a crucial process for the pattern formation in tissues, in particular during embryogenesis. Since the involved cell interactions are complex and difficult to measure individually in experiments,…

Cell Behavior · Quantitative Biology 2022-09-21 Florian Franke , Sebatian Aland , Hans-Joachim Böhme , Anja Voss-Böhme , Steffen Lange

Interactions between crawling cells, which are essential for many biological processes, can be quantified by measuring cell-cell collisions. Conventionally, experiments of cell-cell collisions are conducted on two-dimensional flat…

Biological Physics · Physics 2025-10-24 Yongtian Luo , Amrinder S. Nain , Brian A. Camley

Experimental evidence lends support to the conjecture that the ability of chains of cells to sense the gradient of an external chemical concentration could rely on cell-to-cell communication. This is the basis for the gradient sensing…

Quantitative Methods · Quantitative Biology 2021-02-24 Dallas Foster , Collin Victor , Brian Frost , Juan M. Restrepo

We propose a model for cell polarization as a response to an external signal which results in a system of PDEs for different variants of a protein on the cell surface and interior respectively. We study stationary states of this model in…

Analysis of PDEs · Mathematics 2019-02-18 Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

The one-dimensional contact process is analyzed by a cluster approximation. In this approach, the hierarchy of rate equations for the densities of finite length empty intervals are truncated under the assumption that adjacent intervals are…

Condensed Matter · Physics 2009-10-22 E. Ben-Naim , P. L. Krapivsky

This paper investigates integrated localization and communication in a multi-cell system and proposes a coordinated beamforming algorithm to enhance target localization accuracy while preserving communication performance. Within this…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Meidong Xia , Wei Xu , Jindan Xu , Zhenyao He , Zhaohui Yang , Derrick Wing Kwan Ng

Eukaryotic cells sense chemical gradients to decide where and when to move. Clusters of cells can sense gradients more accurately than individual cells by integrating measurements of the concentration made across the cluster. Is this…

Cell Behavior · Quantitative Biology 2021-10-22 Emiliano Perez Ipiña , Brian A. Camley