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Epithelial monolayers are a central building block of complex organisms. Topological defects have emerged as important elements for single cell behavior in flat epithelia. Here we theoretically study such defects in a three-dimensional…

Biological Physics · Physics 2025-02-19 Oliver M. Drozdowski , Ulrich S. Schwarz

Two-dimensional particle-in-cell (PIC) simulations explore the collisionless tearing instability developing in a Harris equilibrium configuration in a pair (electron-positron) plasma, with no guide field, for a range of parameters from…

Plasma Physics · Physics 2024-10-10 K. M. Schoeffler , B. Eichmann , F. Pucci , M. E. Innocenti

The shearing sheet model of a galactic disk is studied anew. The theoretical description of its dynamics is based on three building blocks: Stellar orbits, which are described here in epicyclic approximation, the collisionless Boltzmann…

Astrophysics · Physics 2009-10-31 B. Fuchs

Recently, we developed a theory of a geometrically growing system. Here we show that the theory can explain some phenomena of power-law distribution including classical demographic and economic and novel pandemic instances, without…

Physics and Society · Physics 2023-02-28 Kim Chol-jun

Mixing layers can grow in time or space by vortex pairings that succeed each other in a nearly self-similar way. We use a point vortex model to study how confinement eventually limits this growth process, leading us to propose a wavelength…

Fluid Dynamics · Physics 2018-05-16 Cristobal Arratia , Saviz Mowlavi , Francois Gallaire

The generation mechanism of growth strains is investigated theoretically by developing an elastic analysis of a wood cell viewed as a composite tube, with layers composed of a ligno-cellulosic material of varying composition and…

Classical Physics · Physics 2016-08-16 François Sassus , Tancrède Alméras , Joseph Gril , Hiroyuki Yamamoto

We present the results of a combined experimental and theoretical investigation of the surface-tension-driven coalescence of flexible structures. Specifically, we consider the dynamics of the rise of a wetting liquid between flexible sheets…

Fluid Dynamics · Physics 2015-05-19 Camille Duprat , Jeffrey M. Aristoff , Howard A. Stone

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

Quantitative Methods · Quantitative Biology 2009-11-13 Carlos Escudero

We present some results of Monte Carlo simulations for the deposition of particles of different sizes on a two-dimensional substrate. The particles are linear, height one, and can be deposited randomly only in the two, $x$ and $y$…

Statistical Mechanics · Physics 2010-06-15 F. L. Forgerini , W. Figueiredo

Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the…

Biological Physics · Physics 2018-12-12 John J. Williamson , Guillaume Salbreux

Morphological trends in growing colonies of living cells are at the core of physiological and evolutionary processes. Using active gel equations, which include cell division, we show that shape changes during the growth can be regulated by…

Soft Condensed Matter · Physics 2016-07-27 Amin Doostmohammadi , Sumesh P. Thampi , Julia M. Yeomans

Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are now known, the system level regulation of growth is still…

Tissues and Organs · Quantitative Biology 2015-06-03 Alberto Puliafito , Lars Hufnagel , Pierre Neveu , Sebastian Streichan , Alex Sigal , Deborah K. Fygenson , Boris I. Shraiman

Universality of interfacial roughness in growing epithelial tissue has remained a controversial issue. Kardar-Parisi-Zhang (KPZ) and Molecular Beam Epitaxy (MBE) universality classes have been reported among other behaviors including total…

Soft Condensed Matter · Physics 2022-03-31 Mahmood Mazarei , Jan Åström , Jan Westerholm , Mikko Karttunen

Cells forming various epithelial tissues have a strikingly universal distribution for the number of their edges. It is generally assumed that this topological feature is predefined by the statistics of individual cell divisions in growing…

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

Soft Condensed Matter · Physics 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi

The hygro-mechanical behavior of a hierarchical cellular material, i.e. growth rings of softwood is investigated using a two-scale micro-mechanics model based on a computational homogenization technique. The lower scale considers the…

Materials Science · Physics 2015-09-22 Ahmad Rafsanjani , Dominique Derome , Falk K. Wittel , Jan Carmeliet

We investigate the scaling behaviour of a singular perturbation model within the geometrically linearized theory of elasticity involving data of higher lamination order. We study boundary data which are of staircase type and show rather…

Analysis of PDEs · Mathematics 2025-11-17 Lennart Machill , Angkana Rüland

The elastic response of the crystalline sheet to the stretching deformation in the form of wrinkles has been extensively investigated. In this work, we extend this fundamental scientific question to the plastic regime by exploring the…

Soft Condensed Matter · Physics 2025-06-09 Ranzhi Sun , Zhenwei Yao

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

When cell sheets fold during development, their apical or basal surfaces constrict and cell shapes approach the geometric singularity in which these surfaces vanish. Here, we reveal the mechanical consequences of this geometric singularity…

Soft Condensed Matter · Physics 2025-12-12 Chandraniva Guha Ray , Pierre A. Haas