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Neurons in the visual cortex respond best to rod-like stimuli of given orientation. While the preferred orientation varies continuously across most of the cortex, there are prominent pinwheel centers around which all orientations a re…

Statistical Mechanics · Physics 2009-11-10 Ha Youn Lee , Mehdi Yahyanejad , Mehran Kardar

Why do neurons encode information the way they do? Normative answers to this question model neural activity as the solution to an optimisation problem; for example, the celebrated efficient coding hypothesis frames neural activity as the…

Neurons and Cognition · Quantitative Biology 2026-03-06 William Dorrell , Peter E. Latham , James Whittington

We study the problem of optimal oculomotor control during the execution of visual search tasks. We introduce a computational model of human eye movements, which takes into account various constraints of the human visual and oculomotor…

Neurons and Cognition · Quantitative Biology 2018-08-30 Alexander Yurievich Vasilyev

Grid cells in the brain respond when an animal occupies a periodic lattice of "grid fields" during spatial navigation. The grid scale varies along the dorso-ventral axis of the entorhinal cortex. We propose that the grid system minimizes…

Neurons and Cognition · Quantitative Biology 2018-05-14 Xue-Xin Wei , Jason Prentice , Vijay Balasubramanian

The human brain is organized in functional modules. Such an organization presents a basic conundrum: modules ought to be sufficiently independent to guarantee functional specialization and sufficiently connected to bind multiple processors…

Biological Physics · Physics 2015-05-27 Lazaros K. Gallos , Hernan A. Makse , Mariano Sigman

In the mammalian brain, many neuronal ensembles are involved in representing spatial structure of the environment. In particular, there exist cells that encode the animal's location and cells that encode head direction. A number of studies…

Neurons and Cognition · Quantitative Biology 2021-08-10 Y. Dabaghian

Extracting physical laws from observation data is a central challenge in many diverse areas of science and engineering. We propose Optimal Control Neural Networks (OCN) to learn the laws of vector fields in dynamical systems, with no…

Dynamical Systems · Mathematics 2023-12-05 Xuping Tian , Baskar Ganapathysubramanian , Hailiang Liu

This paper addresses a large class of vector optimization problems in infinite-dimensional spaces with respect to two important binary relations derived from domination structures. Motivated by theoretical challenges as well as by…

Optimization and Control · Mathematics 2021-02-17 Truong Q. Bao , Boris S. Mordukhovich , Antoine Soubeyran , Christiane Tammer

How does the brain optimize sensory information for decision-making in new tasks? One hypothesis suggests learning reduces redundancy in neural representations to improve efficiency, while another, based on Bayesian inference, predicts…

Neurons and Cognition · Quantitative Biology 2026-03-10 Shizhao Liu , Anton Pletenev , Ralf M. Haefner , Adam C. Snyder

Neurons encode and transmit information in spike sequences. However, despite the effort devoted to quantify their information content, little progress has been made in this regard. Here we use a nonlinear method of time-series analysis…

Neurons and Cognition · Quantitative Biology 2020-02-19 Cristian Estarellas , Maria Masoliver , Cristina Masoller , Claudio Mirasso

Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski

The neuronal networks in the mammals cortex are characterized by the coexistence of hierarchy, modularity, short and long range interactions, spatial correlations, and topographical connections. Particularly interesting, the latter type of…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa , Luis Diambra

The goal of this paper is to investigate distributed temporal difference (TD) learning for a networked multi-agent Markov decision process. The proposed approach is based on distributed optimization algorithms, which can be interpreted as…

Machine Learning · Computer Science 2025-05-14 Han-Dong Lim , Donghwan Lee

Deep neural networks (DNNs) have become the de facto learning mechanism in different domains. Their tendency to perform unreliably on out-of-distribution (OOD) inputs hinders their adoption in critical domains. Several approaches have been…

Machine Learning · Computer Science 2020-06-26 Vahdat Abdelzad , Krzysztof Czarnecki , Rick Salay

Primate visual system samples different parts of the world unevenly. The part of the visual scene corresponding to the eye center is represented densely, while away from the center the sampling becomes progressively sparser. Such…

Neurons and Cognition · Quantitative Biology 2010-02-24 Alexei A. Koulakov

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Inspired by the prevalence of recurrent circuits in biological brains, we investigate the degree to which directionality is a helpful inductive bias for artificial neural networks. Taking directionality as topologically-ordered information…

Machine Learning · Computer Science 2025-07-22 Yiding Song

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Davood Karimi , Ali Gholipour

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

Neural networks trained with SGD were recently shown to rely preferentially on linearly-predictive features and can ignore complex, equally-predictive ones. This simplicity bias can explain their lack of robustness out of distribution…

Machine Learning · Computer Science 2022-09-13 Damien Teney , Ehsan Abbasnejad , Simon Lucey , Anton van den Hengel