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To explore the coupling between a growing population of microorganisms such as E. coli and a nonuniform nutrient distribution, we formulate a minimalistic model. It consists of active Brownian particles that divide and grow at a…

Biological Physics · Physics 2024-01-11 Till Welker , Holger Stark

We observe that small drops of a Bacillus subtilis suspension deposited on agar strongly increase in volume while similar bacteria-void drops do not. By measuring the bacterial concentration within the drop at different heights, we show…

Soft Condensed Matter · Physics 2017-07-31 Marc Hennes , Julien Tailleur , Gaëlle Charron , Adrian Daerr

We introduce an in silico model for the initial spread of an aberrant phenotype with Warburg-like overflow metabolism within a healthy homeostatic tissue in contact with a nutrient reservoir (the blood), aimed at characterizing the role of…

Molecular Networks · Quantitative Biology 2017-06-09 Jorge Fernandez-de-Cossio-Diaz , Andrea De Martino , Roberto Mulet

We present a new microscopic model of granular medium to study the role of dynamical correlations and the onset of spatial order induced by the inelasticity of the interactions. In spite of its simplicity, it features several different…

Statistical Mechanics · Physics 2009-11-07 A. Baldassarri , U. Marini Bettolo Marconi , A. Puglisi

We characterize cell motion in experiments and show that the transition to collective motion in colonies of gliding bacterial cells confined to a monolayer appears through the organization of cells into larger moving clusters. Collective…

The prospect of new biological and industrial applications that require communication in micro-scale, encourages research on the design of bio-compatible communication networks using networking primitives already available in nature. One of…

Information Theory · Computer Science 2012-05-23 Arash Einolghozati , Mohsen Sardari , Ahmad Beirami , Faramarz Fekri

Motivated by the observation that anomalous diffusion is a realistic feature in the dynamics of biological populations, we investigate its implications in a paradigmatic model for the evolution of a single species density $u(x,t)$. The…

Biological Physics · Physics 2012-12-05 Eduardo H. Colombo , Celia Anteneodo

An epidemiological model which incorporates synergistic effects that allow the infectivity and/or susceptibility of hosts to be dependent on the number of infected neighbours is proposed. Constructive synergy induces an exploitative…

Populations and Evolution · Quantitative Biology 2015-03-19 Francisco J. Perez-Reche , Jonathan J. Ludlam , Sergei N. Taraskin , Christopher A. Gilligan

The evolutionary success of bacteria lies in their ability to form complex surface-associated communities in diverse biophysical settings. However, it remains poorly understood how compliance of soft surfaces, measured in terms of their…

Soft Condensed Matter · Physics 2025-08-05 Garima Rani , Anupam Sengupta

Bacterial colonies are abundant on living and nonliving surfaces and are known to mediate a broad range of processes in ecology, medicine, and industry. Although extensively researched, from single cells to demographic scales, a…

Soft Condensed Matter · Physics 2018-09-14 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

Many bacterial species exchange signaling molecules to coordinate population-wide responses. For this process known as quorum sensing the concentration of the respective molecules is crucial. Here we consider the interaction between…

Biological Physics · Physics 2018-11-14 Vera Bettenworth , Matthew McIntosh , Anke Becker , Bruno Eckhardt

We study the spatial patterns formed by a system of interacting particles where the mobility of any individual is determined by the population crowding at two different spatial scales. In this way we model the behavior of some biological…

Statistical Mechanics · Physics 2015-07-08 Ricardo Martínez-García , Clara Murgui , Emilio Hernández-García , Cristóbal López

Cellular self-assembly and organization are fundamental steps for the development of biological tissues. In this paper, within the framework of a cellular automata model, we address how an ordered tissue pattern spontaneously emerges from a…

Biological Physics · Physics 2019-10-24 Debangana Mukhopadhyay , Rumi De

We consider a system of interacting diffusions labeled by a geographic space that is given by the hierarchical group $\Omega_N$ of order $N\in\mathbb{N}$. Individuals live in colonies and are subject to resampling and migration as long as…

Probability · Mathematics 2021-10-07 Andreas Greven , Frank den Hollander , Margriet Oomen

Step meandering due to a deterministic morphological instability on vicinal surfaces during growth is studied. We investigate nonlinear dynamics of a step model with asymmetric step kinetics, terrace and line diffusion, by means of a…

Statistical Mechanics · Physics 2009-10-31 F. Gillet , O. Pierre-Louis , C. Misbah

Growing tissue and bacterial colonies are active matter systems where cell divisions and cellular motion generate active stress. Although they operate in the non-equilibrium regime, these biological systems can form large-scale ordered…

Biological Physics · Physics 2019-05-28 Yusuf Ilker Yaman , Esin Demir , Roman Vetter , Askin Kocabas

Various rod-shaped bacteria such as the canonical gram negative Escherichia coli or the well-studied gram positive Bacillus subtilis divide symmetrically after they approximately double their volume. Their size at division is not constant,…

Cell Behavior · Quantitative Biology 2015-06-18 Ariel Amir

Aggregation-diffusion equations are foundational tools for modelling biological aggregations. Their principal use is to link the collective movement mechanisms of organisms to their emergent space use patterns in a concrete mathematical…

Populations and Evolution · Quantitative Biology 2025-04-16 Jonathan R. Potts

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

Analysis of PDEs · Mathematics 2026-01-07 Romina Travaglini , João Miguel Oliveira

We address the question: Why may reaction-diffusion equations with hysteretic nonlinearities become ill-posed and how to amend this? To do so, we discretize the spatial variable and obtain a lattice dynamical system with a hysteretic…

Analysis of PDEs · Mathematics 2017-11-28 Pavel Gurevich , Sergey Tikhomirov