English
Related papers

Related papers: Toy model for molecular motors

200 papers

In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high. However, using two-state models, we…

Biological Physics · Physics 2015-03-06 Yunxin Zhang

Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

Biological Physics · Physics 2012-09-28 Bartosz Lisowski , Michał Żabicki

In a single molecule assay, the motion of a molecular motor is often inferred from measuring the stochastic trajectory of a large probe particle attached to it. We discuss a simple model for this generic set-up taking into account…

Statistical Mechanics · Physics 2012-11-22 Eva Zimmermann , Udo Seifert

We examine the dependence of the physical quantities of the rotatory molecular motor, such as the rotation velocity and the proton translocation rate, on the chemical reaction rate using the model based only on diffusion process. A peculiar…

Biological Physics · Physics 2009-11-10 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

We study a Markov random process describing a muscle molecular motor behavior. Every motor is either bound up with a thin filament or unbound. In the bound state the motor creates a force proportional to its displacement from the neutral…

Mathematical Physics · Physics 2009-11-13 Yu. Kondratiev , E. Pechersky , S. Pirogov

Properties of transport of molecular motors are investigated. A simplified model based on the concept of Brownian ratchets is applied. We analyze a stochastic equation of motion by means of numerical methods. The transport is systematically…

Statistical Mechanics · Physics 2011-12-07 Lukasz Machura , Marcin Kostur , Jerzy Luczka

We propose a two-dimensional model for a complete description of the dynamics of molecular motors, including both the processive movement along track filaments and the dissociation from the filaments. The theoretical results on the…

Biomolecules · Quantitative Biology 2009-11-10 Ping Xie , Shuo-Xing Dou , Peng-Ye Wang

Motivated by experimental results on the interplay between molecular motors and tau proteins, we extend lattice-based models of intracellular transport to include a second species of particle which locally influences the motor-filament…

Subcellular Processes · Quantitative Biology 2010-04-27 H. Grzeschik , R. J. Harris , L. Santen

In single-molecule experiments, the dynamics of molecular motors are often observed indirectly by measuring the trajectory of an attached bead in a motor-bead assay. In this work, we propose a method to extract the step size and stalling…

Statistical Mechanics · Physics 2023-05-05 Benjamin Ertel , Jann van der Meer , Udo Seifert

A simple tight-coupling model of a molecular chemical engine is proposed. The efficiency of the chemical engine and its average velocity can be explicitly calculated. The diffusion constant is evaluated approximately using the fluctuation…

Statistical Mechanics · Physics 2009-11-11 Hidetsugu Sakaguchi

Current-induced phenomena are often obscured by Joule heating, and their steady states are difficult to analyze in large open systems. We introduce a translationally invariant asymmetric-hopping model as an effective bulk description of…

Mesoscale and Nanoscale Physics · Physics 2026-05-12 Yoshihiro Michishita

The mathematical formulation of the model for molecular movement of single motor proteins driven by cyclic biochemical reactions in an aqueous environment leads to a drifted Brownian motion characterized by coupled diffusion equations. In…

Statistical Mechanics · Physics 2007-05-23 Hong Qian

We present a theoretical treatment of energy transfer in a molecular motor described in terms of overdamped Brownian motion on a multidimensional tilted periodic potential. The tilt acts as a thermodynamic force driving the system out of…

Soft Condensed Matter · Physics 2013-10-11 K. J. Challis , Michael W. Jack

This work deals with the overdamped motion of a particle in a fluctuating one-dimensional periodic potential. If the potential has no inversion symmetry and its fluctuations are asymmetric and correlated in time, a net flow can be generated…

Condensed Matter · Physics 2016-10-26 Enrique Abad , Andreas Mielke

Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models. The transport of the particles is viewed…

Soft Condensed Matter · Physics 2009-11-13 Maxim N. Artyomov , Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky

The output of a motor is work, while the output of a clock is information. Here it is discussed how a molecular motor can produce both, work and information, depending on the load. If the ratio of the backward and forward stepping rates of…

Chemical Physics · Physics 2022-04-13 Henry Hess

The diffusion of a molecular motor in the presence of a constant external force is considered on the basis of a simple theoretical model. The motor is represented by a Brownian particle moving in a series of parabolic potentials placed…

Statistical Mechanics · Physics 2016-06-01 Ryota Shinagawa , Kazuo Sasaki

We consider the asymptotic behavior of an evolving weakly coupled Fokker-Planck system of two equations set in a periodic environment. The magnitudes of the diffusion and the coupling are respectively proportional and inversely proportional…

Analysis of PDEs · Mathematics 2014-02-24 Sepideh Mirrahimi , Panagiotis E. Souganidis

The movement of motor particles consisting of one or several molecular motors bound to a cargo particle is studied theoretically. The particles move on patterns of immobilized filaments. Several patterns are described for which the motor…

Statistical Mechanics · Physics 2009-11-11 Stefan Klumpp , Reinhard Lipowsky

The nonequilibrium response and fluctuations of Markovian systems, both near and far from equilibrium, are best understood by varying their parameters along dynamical equivalence classes. In this note, I illustrate this approach for an…

Statistical Mechanics · Physics 2024-04-03 David Andrieux