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Many of the commonly used methods for orthology detection start from mutually most similar pairs of genes (reciprocal best hits) as an approximation for evolutionary most closely related pairs of genes (reciprocal best matches). This…

Detection of sparse signals arises in a wide range of modern scientific studies. The focus so far has been mainly on Gaussian mixture models. In this paper, we consider the detection problem under a general sparse mixture model and obtain…

Information Theory · Computer Science 2012-11-13 T. Tony Cai , Yihong Wu

Uniform sampling of simple graphs having a given degree sequence is a known problem with exponential complexity in the square of the mean degree. For undirected graphs, randomised approximation algorithms have nonetheless been shown to…

Probability · Mathematics 2022-06-28 Femke van Ieperen , Ivan Kryven

This paper provides a new similarity detection algorithm. Given an input set of multi-dimensional data points, where each data point is assumed to be multi-dimensional, and an additional reference data point for similarity finding, the…

Artificial Intelligence · Computer Science 2017-07-12 Yariv Aizenbud , Amir Averbuch , Gil Shabat , Guy Ziv

Sequential change-point detection when the distribution parameters are unknown is a fundamental problem in statistics and machine learning. When the post-change parameters are unknown, we consider a set of detection procedures based on…

Statistics Theory · Mathematics 2017-12-06 Yang Cao , Liyan Xie , Yao Xie , Huan Xu

We consider two independent binary i.i.d. random strings $X$ and $Y$ of equal length $n$ and the optimal alignments according to a symmetric scoring functions only. We decompose the space of scoring functions into five components. Two of…

Probability · Mathematics 2017-08-02 Jun Tao Duan , Heinrich Matzinger , Ionel Popescu

The assumption that training and testing samples are generated from the same distribution does not always hold for real-world machine-learning applications. The procedure of tackling this discrepancy between the training (source) and…

Machine Learning · Computer Science 2018-12-05 Debasmit Das , C. S. George Lee

String matching algorithm plays the vital role in the Computational Biology. The functional and structural relationship of the biological sequence is determined by similarities on that sequence. For that, the researcher is supposed to aware…

Data Structures and Algorithms · Computer Science 2014-01-30 Pandiselvam. P , Marimuthu. T , Lawrance. R

Alignment-based conformance checking is the state-of-the-art approach for comparing observed process executions with normative process models. The standard exact solution relies on an A*-based heuristic search, which can exhibit exponential…

Artificial Intelligence · Computer Science 2026-05-27 Izack Cohen

We consider detecting change points in the correlation structure of streaming data with minimum assumptions posed on the underlying data distribution. Detection statistics are constructed for dense and sparse change settings, based on…

Methodology · Statistics 2026-02-17 Jie Gao , Liyan Xie , Zhaoyuan Li

Genome sequencing technology has improved significantly in few last years and resulted in abundance genetic data. Artificial intelligence has been employed to analyze genetic data in response to its sheer size and variability. Gene…

Genomics · Quantitative Biology 2023-03-17 Muhammad Anwari Leksono , Ayu Purwarianti

Local density-based score normalization is an effective component of distance-based embedding methods for anomalous sound detection, particularly when data densities vary across conditions or domains. In practice, however, performance…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-24 Kevin Wilkinghoff , Gordon Wichern , Jonathan Le Roux , Zheng-Hua Tan

This paper addresses detecting anomalous patterns in images, time-series, and tensor data when the location and scale of the pattern is unknown a priori. The multiscale scan statistic convolves the proposed pattern with the image at various…

Statistics Theory · Mathematics 2018-06-22 James Sharpnack

This paper considers the change-point problem for finite sequences of networks. To avoid the difficulty of computing the normalization coefficient, such as in Exponential random graphical models (ERGMs) and Markov networks, we construct a…

Statistics Theory · Mathematics 2021-01-19 Lei Qiao , Dong Han

Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample…

Genomics · Quantitative Biology 2013-03-19 Heng Li

We study problem-dependent rates, i.e., generalization errors that scale near-optimally with the variance, the effective loss, or the gradient norms evaluated at the "best hypothesis." We introduce a principled framework dubbed "uniform…

Machine Learning · Statistics 2020-12-25 Yunbei Xu , Assaf Zeevi

Discovering fine-grained categories from coarsely labeled data is a practical and challenging task, which can bridge the gap between the demand for fine-grained analysis and the high annotation cost. Previous works mainly focus on…

Machine Learning · Computer Science 2023-10-17 Wenbin An , Feng Tian , Wenkai Shi , Yan Chen , Qinghua Zheng , QianYing Wang , Ping Chen

This paper considers the problems of detecting a change point and estimating the location in the correlation matrices of a sequence of high-dimensional vectors, where the dimension is large enough to be comparable to the sample size or even…

Methodology · Statistics 2023-11-07 Zhaoyuan Li , Jie Gao

We propose a novel method that tackles the problem of unsupervised domain adaptation for semantic segmentation by maximizing the cosine similarity between the source and the target domain at the feature level. A segmentation network mainly…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Inseop Chung , Daesik Kim , Nojun Kwak

Recently, interest has grown in exploring the hypothesis that neural activity conveys information through precise spiking motifs. To investigate this phenomenon, various algorithms have been proposed to detect such motifs in Single Unit…

Neurons and Cognition · Quantitative Biology 2023-09-27 Laurent U Perrinet