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Comments: 6 pages RevTeX, 6 Postscript figures. We review a statistical mechanics treatment of the stability of globular proteins based on a simple model Hamiltonian taking into account protein self interactions and protein-water…

Condensed Matter · Physics 2009-10-31 Alex Hansen , Mogens H. Jensen , Kim Sneppen , Giovanni Zocchi

Phase diagrams of some globular proteins have a fluid-fluid transition as well as a fluid-crystal transition. Homogeneous nucleation of the crystal from the fluid phase near the critical point of the fluid-fluid transition is examined. As…

Soft Condensed Matter · Physics 2009-10-31 Richard P. Sear

An all-atom model of proteins is used to show that the same sequence of amino acids can have many alternative structures, that are very distant from, and that can be as stable as, the corresponding native structure. Such alternative…

Biological Physics · Physics 2008-02-11 Leonor Cruzeiro

Proteins, chain molecules of amino acids, behave in ways which are similar to each other yet quite distinct from standard compact polymers. We demonstrate that the Flory theorem, derived for polymer melts, holds for compact protein native…

Biomolecules · Quantitative Biology 2009-11-11 Jayanth R. Banavar , Trinh Xuan Hoang , Amos Maritan

We assume that the protein folding process follows two autonomous steps: the conformational search for the native, mainly ruled by the hydrophobic effect; and, the final adjustment stage, which eventually gives stability to the native. Our…

Biological Physics · Physics 2016-07-27 J. P. Dal Molin , A. Caliri

Deformations of amorphous polymer networks prepared with significant concentrations of liquid crystalline mesogens have been recently reported to undergo mechanotropic phase transitions. Here, we report that these mechanotropic phase…

Soft Condensed Matter · Physics 2021-06-09 Jeremy A. Koch , Jeremy A. Herman , Timothy J. White

The phase structure of self-avoiding polymerized membranes is studied by extensive Hybrid Monte Carlo simulations. Several folding transitions from the flat to a collapsed state are found. Using a suitable order parameter and finite size…

Condensed Matter · Physics 2009-10-28 Christian Münkel , Dieter W. Heermann

In a nematic gel, the appearance of nematic order is accompanied by a spontaneous elongation of the gel parallel to the nematic director. If such a gel is made chiral, it has a tendency to form a cholesteric helical texture, in which local…

Soft Condensed Matter · Physics 2009-11-07 Robert A. Pelcovits , Robert B. Meyer

Energetic correlations due to polymeric constraints and the locality of interactions, in conjunction with the apriori specification of the existence of a particularly low energy state, provides a method of introducing the aspect of minimal…

Condensed Matter · Physics 2009-10-28 Steven S. Plotkin , Jin Wang , Peter G. Wolynes

We study pattern formation in gels undergoing simultaneous phase separation and orientational ordering. A 2D numerical simulation is performed using a minimal model of nonlinear elasticity with density-anisotropy coupling. For strong…

Soft Condensed Matter · Physics 2009-11-07 Nariya Uchida

Liquid crystals in two dimensions do not support long-ranged nematic order, but a quasi-nematic phase where the orientational correlations decay algebraically is possible. The transition from the isotropic to the quasi-nematic phase can be…

Statistical Mechanics · Physics 2014-12-30 Richard L. C. Vink

We study at- and out-of-equilibrium dynamics of a single homopolymer chain at low temperature using molecular dynamics simulations. The main quantities of interest are the average root mean square displacement of the monomers below the…

Soft Condensed Matter · Physics 2009-11-07 Nikolay V. Dokholyan , Estelle Pitard , Sergey V. Buldyrev , H. Eugene Stanley

When a chiral isotropic elastomer is brought to low temperature cholesteric phase, the nematic degree of freedom tends to order and form a helix. Due to the nemato-elastic coupling, this also leads to elastic deformation of the polymer…

Soft Condensed Matter · Physics 2009-11-13 Xiangjun Xing , Aparna Baskaran

Protein folding is the intricate process by which a linear sequence of amino acids self-assembles into a unique three-dimensional structure. Protein folding kinetics is the study of pathways and time-dependent mechanisms a protein undergoes…

Machine Learning · Computer Science 2023-09-19 Vijay Arvind. R , Haribharathi Sivakumar , Brindha. R

We introduce an exactly solvable statistical-mechanical model of the hydration of non-polar compounds, based on grouping water molecules in clusters where hydrogen bonds and isotropic interactions occur; interactions between clusters are…

Statistical Mechanics · Physics 2009-11-07 Pierpaolo Bruscolini , Lapo Casetti

We study the kinetics of the nematic-isotropic transition in a two-dimensional liquid crystal by using a lattice Boltzmann scheme that couples the tensor order parameter and the flow consistently. Unlike in previous studies, we find the…

Soft Condensed Matter · Physics 2009-11-07 Colin Denniston , Enzo Orlandini , J. M. Yeomans

The phase behavior of a cross-linked polymer blend made of two incompatible species, $A$ and $B$, of different chemical nature is analyzed. Besides a homogeneous phase, this system also exhibits two microphases and a phase of total…

Condensed Matter · Physics 2007-05-23 Edilson Vargas , Marcia C. Barbosa

Chiral polymers are ubiquitous in nature and in the cellular context they are often found in association with membranes. Here we show that surface bound polymers with an intrinsic twist and anisotropic bending stiffness can exhibit a sharp…

Soft Condensed Matter · Physics 2016-04-26 David A. Quint , Ajay Gopinathan , Gregory M. Grason

We study random close packed systems of magnetic spheres by Monte Carlo simulations in order to estimate their phase diagram. The uniaxial anisotropy of the spheres makes each of them behave as a single Ising dipole along a fixed easy axis.…

Statistical Mechanics · Physics 2019-10-09 J. J. Alonso , B. Alles , V. Russier

Dry active matter in an anisotropic medium is of experimental relevance, and the interplay between anisotropy and the dynamics of the active matter remains under-explored. Here, we derive the hydrodynamic equations of a generic dry polar…

Soft Condensed Matter · Physics 2025-07-22 Leiming Chen , Chiu Fan Lee , John Toner
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