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The phase transition from the isotropic (I) to nematic (N) liquid crystalline suspension of F-actin of average length $3~\mu$m or above was studied by local measurements of optical birefringence and protein concentration. Both parameters…

Biological Physics · Physics 2009-11-07 Jorge Viamontes , Jay X. Tang

Filamentous actin, a species of dynamic protein polymers, is one of the main components of the cytoskeleton of eukaryotic cells. We formulate a class of models that predict the possibility of bistable steady states in populations of dynamic…

Biomolecules · Quantitative Biology 2024-06-14 Panayiotis Foteinopoulos , Bela M. Mulder

Crumpled paper or drapery patterns are everyday examples of how elastic sheets can respond to external forcing. In this Letter, we study experimentally a novel sort of forcing. We consider a circular flexible plate clamped at its center and…

Soft Condensed Matter · Physics 2013-08-26 Lionel Schouveiler , Christophe Eloy

The dynamics of a flexible filament sedimenting in a viscous fluid are explored analytically and numerically. Compared to the well-studied case of sedimenting rigid rods, the introduction of filament compliance is shown to cause a…

Fluid Dynamics · Physics 2013-11-04 Lei Li , Harishankar Manikantan , David Saintillan , Saverio E. Spagnolie

We study the over-damped dynamics of individual one-dimensional elastic filaments subjected to a chiral active force which propels each point of the filament at a fixed angle relative to the tangent vector of the filament at that point.…

Soft Condensed Matter · Physics 2026-03-09 Chanania Steinbock , Daniel A. Beller

Building on the results of our computer simulation (ArXiv cond-mat/0503573)we develop a theoretical description of the motion of a bead, embedded in a network of semiflexible polymers, and responding to an applied force. The theory reveals…

Soft Condensed Matter · Physics 2013-05-29 N. Ter-Oganessian , D. A. Pink , A. Boulbitch

We develop a model to describe the force generated by the polymerization of an array of parallel biofilaments. The filaments are assumed to be coupled only through mechanical contact with a movable barrier. We calculate the filament density…

Statistical Mechanics · Physics 2015-05-20 K. Tsekouras , D. Lacoste , K. Mallick , J. -F. Joanny

The dynamic behavior of bundles of actin filaments growing against a loaded obstacle is investigated through a generalized version of the standard multi filaments Brownian Ratchet model in which the (de)polymerizing filaments are treated…

Biological Physics · Physics 2019-05-22 Alessia Perilli , Carlo Pierleoni , Jean-Paul Ryckaert

In this fluid dynamics video we explore an array of different possible dynamics for a flexible filament sedimenting in a viscous fluid. The time-dependent shapes and trajectories of the filament are determined analytically and numerically…

Fluid Dynamics · Physics 2013-10-03 Harishankar Manikantan , Lei Li , David Saintillan , Saverio E. Spagnolie

We establish the Statistical Mechanics framework for a bundle of Nf living and uncrosslinked actin filaments in a supercritical solution of free monomers pressing against a mobile wall. The filaments are anchored normally to a fixed planar…

Biological Physics · Physics 2016-07-27 Alessia Perilli , Carlo Pierleoni , Giovanni Ciccotti , Jean Paul Ryckaert

We directly visualize single polymers with persistence lengths ranging from $\ell_p=0.05$ to 16 $\mu$m, dissolved in the nematic phase of rod-like {\it fd} virus. Polymers with sufficiently large persistence length undergo a coil-rod…

Composites of flexible and rigid polymers are ubiquitous in biology and industry alike, yet the physical principles determining their mechanical properties are far from understood. Here, we couple force spectroscopy with large-scale…

We have investigated the viscosity and the plateau modulus of actin solutions with a magnetically driven rotating disc rheometer. For entangled solutions we observed a scaling of the plateau modulus versus concentration with a power of 7/5.…

Soft Condensed Matter · Physics 2009-10-30 B. Hinner , M. Tempel , E. Sackmann , K. Kroy , E. Frey

Thin elastic sheets and membranes are known to wrinkle when they are stretched -- the associated physics is highly non-linear. The mechanics of thin films that exhibit unusual behavior upon stretching, when they possess auxetic structure,…

Soft Condensed Matter · Physics 2020-07-22 Alessandra Bonfanti , Atul Bhaskar

The kinetics of the assembly of semiflexible filaments through end-to-end annealing is key to the structure of the cytoskeleton, but is not understood. We analyze this problem through scaling theory and simulations, and uncover a regime…

Soft Condensed Matter · Physics 2023-12-18 Valerio Sorichetti , Martin Lenz

We study force generation by a set of parallel actin filaments growing against a non-rigid obstacle, in presence of an external load. The filaments polymerize by either moving the whole obstacle, with a large energy cost, or by causing…

Subcellular Processes · Quantitative Biology 2016-06-27 Raj Kumar Sadhu , Sakuntala Chatterjee

We present a general dynamical theory of a membrane coupled to an actin cortex containing polymerizing filaments with active stresses and currents, and demonstrate that active membrane dynamics [Phys. Rev. Lett \textbf{84}, 3494 (2000)] and…

Biological Physics · Physics 2015-06-18 Ananyo Maitra , Pragya Srivastava , Madan Rao , Sriram Ramaswamy

We consider a single living semi-flexible filament with persistence length l_p in chemical equilibrium with a solution of free monomers at fixed monomer chemical potential mu_1 and fixed temperature T. While one end of the filament is…

Biological Physics · Physics 2015-10-28 Carlo Pierleoni , Giovanni Ciccotti , Jean-Paul Ryckaert

Mutual uncrossability of polymers generates topological constraints on their conformations and dynamics, which are generally described using the tube model. We imaged confinement tubes for individual polymers within a F-actin solution by…

Soft Condensed Matter · Physics 2009-08-20 M. Romanowska , H. Hinsch , N. Kirchgessner , M. Giesen , M. Degawa , B. Hoffmann , E. Frey , R. Merkel

The transport of deformable particles through porous media underlies a wealth of applications ranging from filtration to oil recovery to the transport and spreading of biological agents. Using direct numerical simulations, we analyze the…

Soft Condensed Matter · Physics 2020-06-09 Brato Chakrabarti , Charles Gaillard , David Saintillan
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