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Related papers: A hierarchical model for aging

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The GREM-like trap model is a continuous time Markov jump process on the leaves of a finite volume $L$-level tree whose transition rates depend on a trapping landscape built on the vertices of the whole tree. We prove that the natural…

Probability · Mathematics 2015-01-14 Véronique Gayrard , Onur Gün

A fluctuation relation for aging systems is introduced, and verified by extensive numerical simulations. It is based on the hypothesis of partial equilibration over phase space regions in a scenario of entropy-driven relaxation. The…

Statistical Mechanics · Physics 2013-04-18 A. Crisanti , M. Picco , F. Ritort

The linear semigroup associated with age-structured diffusive populations is investigated in the $L_1$-setting. A complete determination of its generator is given along with detailed spectral information that imply, in particular, an…

Analysis of PDEs · Mathematics 2022-03-01 Christoph Walker

We consider the dynamics of the disordered trap model, which is known to be completely out-of-equilibrium and to present strong localization effects in its aging phase. We are interested into the influence of an external force, when it is…

Condensed Matter · Physics 2009-11-10 Cecile Monthus

Hierarchical tree structures are common in many real-world systems, from tree roots and branches to neuronal dendrites and biologically inspired artificial neural networks, as well as in technological networks for organizing and searching…

Statistical Mechanics · Physics 2025-02-04 Davide Cipollini , Lambert Schomaker

Aging is a fundamental aspect of living systems that undergo a progressive deterioration of physiological function with age and an increase of vulnerability to disease and death. Living systems, known as complex systems, require complexity…

Populations and Evolution · Quantitative Biology 2010-11-15 Byung Mook Weon , Jung Ho Je

We consider linear age-structured population equations with diffusion. Supposing maximal regularity of the diffusion operator, we characterize the generator and its spectral properties of the associated strongly continuous semigroup. In…

Analysis of PDEs · Mathematics 2012-01-13 Christoph Walker

The network concept is increasingly used for the description of complex systems. Here we summarize key aspects of the evolvability and robustness of the hierarchical network-set of macromolecules, cells, organisms, and ecosystems. Listing…

Molecular Networks · Quantitative Biology 2010-10-05 Huba J. M. Kiss , Agoston Mihalik , Tibor Nanasi , Balint Ory , Zoltan Spiro , Csaba Soti , Peter Csermely

In these lecture notes I describe some of the main theoretical ideas emerged to explain the aging dynamics. This is meant to be a very short introduction to aging dynamics and no previous knowledge is assumed. I will go through simple…

Statistical Mechanics · Physics 2009-11-11 Giulio Biroli

The Chapter is devoted to reviewing the main features of aging in non disordered systems relaxing via domain growth, after an istantaneous temperature quench. Using the autocorrelation and autoresponse functions to gauge the deviation from…

Statistical Mechanics · Physics 2014-12-16 Marco Zannetti

Aging changes including age spots and atherosclerotic plaques develop in an inhomogeneous and accelerated manner. For understanding this phenomenon, some aging changes are analyzed by Misrepair mechanism, a mechanism proposed in…

Other Quantitative Biology · Quantitative Biology 2018-02-07 Jicun Wang-Michelitsch , Thomas Michelitsch

Single-particle tracking offers detailed information about the motion of molecules in complex environments such as those encountered in live cells, but the interpretation of experimental data is challenging. One of the most powerful tools…

Statistical Mechanics · Physics 2022-01-12 Zachary R Fox , Eli Barkai , Diego Krapf

We report results of molecular dynamics simulations of a binary Lennard-Jones system at zero pressure in the undercooled liquid and glassy states. We first follow the evolution of diffusivity and dynamic heterogeneity with temperature and…

Disordered Systems and Neural Networks · Physics 2007-05-23 H. R. Schober

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

Analysis of PDEs · Mathematics 2013-06-11 Martin Kohlmann

We give a general proof of aging for trap models using the arcsine law for stable subordinators. This proof is based on abstract conditions on the potential theory of the underlying graph and on the randomness of the trapping landscape. We…

Probability · Mathematics 2007-05-23 Gerard Ben Arous , Jiri Cerny

Many biological systems and artificial structures are ramified, and present a high geometric complexity. In this work, we propose a space-averaged model of branched systems for conservation laws. From a one-dimensional description of the…

Computational Physics · Physics 2014-10-13 Diego Lopez , Emmanuel de Langre , Sébastien Michelin

We investigate the aging behavior of lattice-gas models with constrained dynamics in which particle exchange with a reservoir is allowed. Such models provide a particularly simple interpretation of aging phenomena as a slow approach to…

Statistical Mechanics · Physics 2009-10-30 Jorge Kurchan , Luca Peliti , Mauro Sellitto

Misrepair accumulation theory is a novel theory in interpreting aging phenomena. With a new concept of Misrepair, this theory reaches a unified understanding of aging: aging of an organism is a result of accumulation of Misrepairs of its…

Tissues and Organs · Quantitative Biology 2017-01-05 Jicun Wang-Michelitsch , Thomas M. Michelitsch

In this paper, we introduce some new notions of aging based on geometric, harmonic means of failure rate and aging intensity function. We define a generalized version of aging functions called specific interval-average geometric hazard…

Statistics Theory · Mathematics 2024-07-02 Subarna Bhattacharjee , Ananda Sen , Sabana Anwar , Aninda Kumar Nanda

We present a field theory to describe the composition of a surface spontaneously exchanging matter with its bulk environment. By only assuming matter conservation in the system, we show with extensive numerical simulations that, depending…

Biological Physics · Physics 2023-08-09 Nirvana Caballero , Karsten Kruse , Thierry Giamarchi
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