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Much evolutionary information is stored in the fluctuations of protein length distributions. The genome size and non-coding DNA content can be calculated based only on the protein length distributions. So there is intrinsic relationship…

Genomics · Quantitative Biology 2008-06-03 Dirson Jian Li , Shengli Zhang

Domain generalization methods aim to learn models robust to domain shift with data from a limited number of source domains and without access to target domain samples during training. Popular domain alignment methods for domain…

Machine Learning · Computer Science 2022-06-17 Wenyu Zhang , Mohamed Ragab , Chuan-Sheng Foo

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

Similarity metrics are a core component of many information retrieval and machine learning systems. In this work we propose a method capable of learning a similarity metric from data equipped with a binary relation. By considering only the…

Machine Learning · Computer Science 2016-04-06 Henry Gouk , Bernhard Pfahringer , Michael Cree

Usage of multiprocessor and multicore computers implies parallel programming. Tools for preparing parallel programs include parallel languages and libraries as well as parallelizing compilers and convertors that can perform automatic…

Mathematical Software · Computer Science 2022-12-12 Pavel Telegin , Anton Baranov , Boris Shabanov , Artem Tikhomirov

Labeling of DNA molecules is a fundamental technique for DNA visualization and analysis. This process was mathematically modeled in [1], where the received sequence indicates the positions of the used labels. In this work, we develop error…

Information Theory · Computer Science 2025-11-04 Dganit Hanania , Eitan Yaakobi

We introduce detector-level entanglement, a unified entanglement concept for identical particles that takes into account the possible deletion of many-particle which-way information through the detection process. The concept implies a…

Methods of performing anomaly detection on high-dimensional data sets are needed, since algorithms which are trained on data are only expected to perform well on data that is similar to the training data. There are theoretical results on…

Machine Learning · Computer Science 2020-11-13 Forrest Laine , Claire Tomlin

There is a growing need for machine learning-based anomaly detection strategies to broaden the search for Beyond-the-Standard-Model (BSM) physics at the Large Hadron Collider (LHC) and elsewhere. The first step of any anomaly detection…

High Energy Physics - Phenomenology · Physics 2023-01-18 Gregor Kasieczka , Radha Mastandrea , Vinicius Mikuni , Benjamin Nachman , Mariel Pettee , David Shih

This study proposes a deep learning-based approach for discovering loops in programming code according to their potential for parallelization. Two genetic algorithm-based code generators were developed to produce two distinct types of code:…

Machine Learning · Computer Science 2025-10-03 Izavan dos S. Correia , Henrique C. T. Santos , Tiago A. E. Ferreira

We present a sequence-based probabilistic formalism that directly addresses co-operative effects in networks of interacting positions in proteins, providing significantly improved contact prediction, as well as accurate quantitative…

Quantitative Methods · Quantitative Biology 2012-07-12 Alan Lapedes , Bertrand Giraud , Christopher Jarzynski

Novelty detection is the process of determining whether a query example differs from the learned training distribution. Previous methods attempt to learn the representation of the normal samples via generative adversarial networks (GANs).…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Chengwei Chen , Yuan Xie , Shaohui Lin , Ruizhi Qiao , Jian Zhou , Xin Tan , Yi Zhang , Lizhuang Ma

BACKGROUND: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. This mode of protein function assignment is mostly…

Quantitative Methods · Quantitative Biology 2007-09-28 Emmanuel D. Levy , Christos A. Ouzounis , Walter R. Gilks , Benjamin Audit

Unsupervised learning of visual similarities is of paramount importance to computer vision, particularly due to lacking training data for fine-grained similarities. Deep learning of similarities is often based on relationships between pairs…

Computer Vision and Pattern Recognition · Computer Science 2017-04-12 Miguel A Bautista , Artsiom Sanakoyeu , Björn Ommer

Single-particle tracking allows to infer the motion of single molecules in living cells. When we observe a long trajectory (more than 100 points), it is possible that the particle switches mode of motion over time. Then, fitting a single…

Methodology · Statistics 2018-04-16 Vincent Briane , Charles Kervrann , Myriam Vimond

As a fundamental problem in many different fields, link prediction aims to estimate the likelihood of an existing link between two nodes based on the observed information. Since this problem is related to many applications ranging from…

Physics and Society · Physics 2014-10-01 Hao Liao , An Zeng , Yi-Cheng Zhang

Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. Delineating recombination events is important in the study of molecular evolution, as inference of such events provides a clearer…

Populations and Evolution · Quantitative Biology 2007-09-13 Cheong Xin Chan , Robert G. Beiko , Mark A. Ragan

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

Repetitive elements are important in genomic structures, functions and regulations, yet effective methods in precisely identifying repetitive elements in DNA sequences are not fully accessible, and the relationship between repetitive…

Genomics · Quantitative Biology 2016-08-03 Changchuan Yin

Techniques for detecting critical phenomena -- phase transitions where correlation length diverges and small perturbations have large effects -- have been developed across multiple fields over nine decades. We survey between six and twelve…

Physics and Society · Physics 2026-03-19 Bruce Stephenson , Robin Macomber