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Gel electrophoresis is a powerful experimental method to probe the topology of DNA and other biopolymers. While there is a large body of experimental work which allows us to accurately separate different topoisomers of a molecule, a full…

Soft Condensed Matter · Physics 2016-02-17 Davide Michieletto , Davide Marenduzzo , Enzo Orlandini

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

Tissues and Organs · Quantitative Biology 2023-03-08 Nen Saito , Shuji Ishihara

Solvent-based techniques usually involve preparing dilute blends of electron-donor and electron-acceptor materials dissolved in a volatile solvent. After some form of coating onto a substrate, the solvent evaporates. An initially…

Mesoscale and Nanoscale Physics · Physics 2012-03-01 Olga Wodo , Baskar Ganapathysubramanian

The topological hypothesis claims that phase transitions in a classical statistical mechanical system are related to changes in the topology of the level sets of the Hamiltonian. So far, the study of this hypothesis has been restricted to…

Statistical Mechanics · Physics 2019-05-01 David Cimasoni , Robin Delabays

We analytically derive an equation describing vesicle evolution in a fluid where some stationary flow is excited regarding that the vesicle shape is close to a sphere. A character of the evolution is governed by two dimensionless…

Soft Condensed Matter · Physics 2009-11-13 V. V. Lebedev , K. S. Turitsyn , S. S. Vergeles

We study a shape evolution framework in which the deformation of shapes from time t to t + dt is governed by a regularized anisotropic elasticity model. More precisely, we assume that at each time shapes are infinitesimally deformed from a…

Optimization and Control · Mathematics 2019-01-01 Dai-Ni Hsieh , Sylvain Arguillère , Nicolas Charon , Michael I. Miller , Laurent Younes

Dimensional evolution between one- ($1D$) and two-dimensional ($2D$) topological phases is investigated systematically. The crossover from a $2D$ topological insulator to its $1D$ limit shows oscillating behavior between a $1D$ ordinary…

Mesoscale and Nanoscale Physics · Physics 2015-06-19 Huaiming Guo , Lin Yang , Shun-Qing Shen

Simulations of nematic-isotropic transition of liquid crystals in two dimensions are performed using an O(2) vector model characterised by non linear nearest neighbour spin interaction governed by the fourth Legendre polynomial $P\_4$. The…

Statistical Mechanics · Physics 2016-08-16 Ana Fariñas-Sanchez , Ricardo Paredes , Bertrand Berche

We experimentally study the shear flow of oil-in-water emulsion droplets in a thin sample chamber with a hopper shape. In this thin chamber, the droplets are quasi-2D in shape. The sample is at an area fraction above jamming and forced to…

Soft Condensed Matter · Physics 2012-11-09 Dandan Chen , Kenneth W. Desmond , Eric R. Weeks

Recent experiments on mucociliary clearance, an important defense against airborne pathogens, have raised questions about the topology of two-dimensional (2D) flows. We introduce a framework for studying ensembles of 2D time-invariant flow…

Fluid Dynamics · Physics 2024-12-30 M. Kamb , J. Byrum , G. Huber , G. Le Treut , S. Mehta , B. Veytsman , D. Yllanes

A non-statistical theory of continuous, but irreversible, evolution can be constructed in terms of the Cartan calculus. The fundamental postulate, for an evolutionary theory which admits irreversible processes, is that the topology of the…

Mathematical Physics · Physics 2007-05-23 R. M. Kiehn

One account of two-dimensional (2D) structural transformations in 2D ferroelectrics predicts an evolution from a structure with Pnm2$_1$ symmetry into a structure with square P4/nmm symmetry and is consistent with experimental evidence,…

Soft Condensed Matter · Physics 2020-05-13 John W. Villanova , Pradeep Kumar , Salvador Barraza-Lopez

Morphogenesis of living systems involves topological shape transformations which are highly unusual in the inanimate world. Here we demonstrate that a droplet of a nematic liquid crystal changes its equilibrium shape from a simply-connected…

Soft Condensed Matter · Physics 2023-07-04 Runa Koizumi , Dmitry Golovaty , Ali Alqarni , Bing-Xiang Li , Peter J. Sternberg , Oleg D. Lavrentovich

The central goal of a dynamical theory of evolution is to abstract the mean evolutionary trajectory in the trait space by considering ecological processes at the level of the individual. In this work, we develop such a theory for a new…

Populations and Evolution · Quantitative Biology 2020-03-25 Vaibhav Madhok

We present a novel framework for the study of disclinations in two-dimensional active nematic liquid crystals, and topological defects in general. The order tensor formalism is used to calculate exact multi-particle solutions of the…

Soft Condensed Matter · Physics 2018-02-28 Dario Cortese , Jens Eggers , Tanniemola B. Liverpool

We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells as well as a contribution to overall tissue shear flow due to…

The Topological Hypothesis states that phase transitions should be related to changes in the topology of configuration space. The necessity of such changes has already been demonstrated. We characterize exactly the topology of the…

Statistical Mechanics · Physics 2007-05-23 S. Risau-Gusman , A. C. Ribeiro-Teixeira , D. A. Stariolo

A limited mobility nonequilibrium solid-on-solid dynamical model for kinetic surface growth is introduced as a simple description for the morphological evolution of a growing interface under random vapor deposition and surface diffusion…

Statistical Mechanics · Physics 2007-05-23 S. Das Sarma , P. Punyindu

We investigate crystalline order on a two-dimensional paraboloid of revolution by assembling a single layer of millimeter-sized soap bubbles on the surface of a rotating liquid, thus extending the classic work of Bragg and Nye on planar…

Soft Condensed Matter · Physics 2008-02-28 Mark J. Bowick , Luca Giomi , Homin Shin , Creighton K. Thomas

T1 transitions, which are localised cell rearrangements, play an important role in the fluidization of epithelial monolayers. Using a multi-phase field model and an active elastic solid model, we show that although each cell undergoes T1…

Biological Physics · Physics 2025-02-11 Harish P. Jain , Richard D. J. G. Ho , Luiza Angheluta