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We present a simple model for biological aging. We studied it through computer simulations and we have found this model to reflect some features of real populations.

Condensed Matter · Physics 2009-10-28 Thadeu J. P. Penna

The sexual version of the Penna model of biological ageing, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving ageing. In particular we want to check how sexual forms of life…

Statistical Mechanics · Physics 2007-05-23 D. Stauffer , P. M. C. de Oliveira , S. Moss de Oliveira , T. J. P. Penna , J. S. Sa' Martins

We succeeded in obtaining exact results of the bit-string model of biological aging for populations whose individuals breed only once. These results are in excellent agreement with those obtained through computer simulations. In addition,…

adap-org · Physics 2009-10-28 T. J. P. Penna , S. Moss de Oliveira

We present a model for biological aging that considers the number of individuals whose (inherited) genetic charge determines the maximum age for death: each individual may die before that age due to some external factor, but never after…

adap-org · Physics 2008-02-03 R. M. C. de Almeida , S. Moss de Oliveira , T. J. P. Penna

Similar to biological evolution and speciation we define a language through a string of 8 or 16 bits. The parent gives its language to its children, apart from a random mutation from zero to one or from one to zero; initially all bits are…

Disordered Systems and Neural Networks · Physics 2009-11-10 Christian Schulze , Dietrich Stauffer

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

Quantitative Methods · Quantitative Biology 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

We have simulated demographic changes in the human population using the Penna microscopic model, based on the simple Monte Carlo method. The results of simulations have shown that during a few generations changes in the genetic pool of a…

Statistical Mechanics · Physics 2007-05-23 A. Laszkiewicz , Sz. Szymczak , S. Cebrat

A bit-string model for the evolution of a population of haploid organisms, subject to competition, reproduction with mutation and selection is studied, using mean field theory and Monte Carlo simulations. We show that, depending on…

Statistical Mechanics · Physics 2009-11-07 Kathia M. Fehsenfeld , Ronald Dickman , Americo T. Bernardes

The present review deals with the computer simulation of biological ageing as well as its demographic consequences for industrialized societies.

Statistical Mechanics · Physics 2016-11-23 Dietrich Stauffer

Monte Carlo simulations of the number of stem cells in human colon crypts allow for fluctuations which kill the population after sufficiently long times.

Cell Behavior · Quantitative Biology 2007-05-23 Dietrich Stauffer , Eytan Domany

In this work we check the occurrence of the Azbel assumption of mortality within the framework of a bit string model for biological ageing. We reproduced the observed feature of linear correspondence between the fitting parameters of the…

adap-org · Physics 2008-02-03 A. Racco , M. Argollo de Menezes , T. J. P. Penna

A stochastic genetic model for biological aging is introduced bridging the gap between the bit-string Penna model and the Pletcher-Neuhauser approach. The phenomenon of exponentially increasing mortality function at intermediate ages and…

Statistical Mechanics · Physics 2007-05-23 Zhi-Feng Huang , Dietrich Stauffer

In this paper the Penna model is reconsidered. With computer simulations we check how the control parameters of the model influence the size of the stable population.

Populations and Evolution · Quantitative Biology 2007-05-23 K. Malarz , M. Sitarz , P. Gronek , A. Dydejczyk

In previous papers of the series we used a combination of optical and near-infrared colours to derive constraints on the relative age structure in globular cluster systems. Here, we present the details, strength and limitations of our…

Astrophysics · Physics 2009-11-10 Maren Hempel , Markus Kissler-Patig

Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population…

Populations and Evolution · Quantitative Biology 2016-02-03 Arian Šajina , Dario Riccardo Valenzano

We present some simple computer simulations that indicate that at short time aging is realized in a simple model of binary glasses. It is interesting to note that modest computer simulations are enough to evidenziate this effect. We also…

Disordered Systems and Neural Networks · Physics 2008-02-03 Giorgio Parisi

The similarity of the evolution of human languages (or alphabets, bird songs, >...) to biological evolution of species is utilized to study with up to $10^9$ people the rise and fall of languages either by macroscopic differential equations…

Physics and Society · Physics 2009-11-11 Dietrich Stauffer , Christian Schulze

This study presents a framework for high-resolution mortality simulations tailored to insured and general populations. Due to the scarcity of detailed demographic-specific mortality data, we leverage Iterative Proportional Fitting (IPF) and…

Applications · Statistics 2025-04-18 Asmik Nalmpatian , Christian Heumann

The bit-string model of biological aging is used to simulate the catastrophic senescence of Pacific Salmon. We have shown that reproduction occuring only once and at a fixed age is the only ingredient needed to explain the catastrophic…

adap-org · Physics 2009-10-28 T. J. P. Penna , S. Moss de Oliveira , Dietrich Stauffer

We introduce a population dynamics model, where individual genomes are represented by bit-strings. Selection is described by death probabilities which depend on these genomes, and new individuals continuously replace the ones that die,…

Statistical Mechanics · Physics 2009-11-10 P. M. C. de Oliveira , J. S. Sa' Martins , D. Stauffer , S. Moss de Oliveira
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