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Is evolution always gradual or can it make leaps? We examine a mathematical model of an evolutionary process on a fitness landscape and obtain analytic solutions for the probability of multi-mutation leaps, that is, several mutations…

Populations and Evolution · Quantitative Biology 2022-10-12 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

We present a modelling framework for the dynamics of cells structured by the concentration of a micromolecule they contain. We derive general equations for the evolution of the cell population and of the extra-cellular concentration of the…

Cell Behavior · Quantitative Biology 2024-10-30 Michael Grinfeld , Nigel Mottram , Jozsef Farkas

We extend our study of a simple model of biological coevolution to its statistical properties. Staring with a complete description in terms of a master equation, we provide its relation to the deterministic evolution equations used in…

Populations and Evolution · Quantitative Biology 2007-05-23 R. K. P. Zia , Per Arne Rikvold

Competition is the main driver of population dynamics, which shapes the genetic composition of populations and the assembly of ecological communities. Neutral models assume that all the individuals are equivalent and that the dynamics is…

Populations and Evolution · Quantitative Biology 2018-04-11 Matan Danino , Nadav M. Shnerb

Current evolutionary biology models usually assume that a phenotype undergoes gradual change. This is in stark contrast to biological intuition, which indicates that change can also be punctuated-the phenotype can jump. Such a jump could…

Populations and Evolution · Quantitative Biology 2020-08-07 Krzysztof Bartoszek

We study the maturation of the antibody population following primary antigen presentation as a global optimization problem. Emphasis is placed on the trade-off between the safety of mutations that lead to local improvements to the…

Quantitative Methods · Quantitative Biology 2007-05-23 Patricia Theodosopoulos , Ted Theodosopoulos

A celebrated and controversial hypothesis conjectures that some biological systems --parts, aspects, or groups of them-- may extract important functional benefits from operating at the edge of instability, halfway between order and…

Statistical Mechanics · Physics 2018-08-01 Miguel A. Munoz

We propose a stochastic model for evolution through mutation and natural selection of a population that evolves on a $\bbT_d^+$ tree. We think of this model as a way of describing the evolution fitness landscape of a population. We obtain…

Probability · Mathematics 2021-04-13 Carolina Grejo , Fabio Lopes , Fábio Machado , Alejandro Roldán-Correa

A population of heterogenous agents compeeting through a minority rule is investigated. Agents which frequently loose are selected for evolution by changing their strategies. The stationary composition of the population resulting for this…

Disordered Systems and Neural Networks · Physics 2009-10-31 Alexei Vazquez

According to the criticality hypothesis, collective biological systems should operate in a special parameter region, close to so-called critical points, where the collective behavior undergoes a qualitative change between different…

Populations and Evolution · Quantitative Biology 2021-06-09 Pascal P. Klamser , Pawel Romanczuk

Self-adaptive dynamics occurs in many physical systems such as socio-economics, neuroscience, or biophysics. We formalize a self-adaptive modeling approach, where adaptation takes place within a set of strategies based on the history of the…

Adaptation and Self-Organizing Systems · Physics 2022-04-01 Konstantin Clauß , Christian Kuehn

Mathematical models play an increasingly important role in the interpretation of biological experiments. Studies often present a model that generates the observations, connecting hypothesized process to an observed pattern. Such generative…

Populations and Evolution · Quantitative Biology 2014-06-18 Steven A. Frank

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random…

Biological Physics · Physics 2009-11-07 L. C. Hsieh , L. F. Luo , F. M. Ji , H. C. Lee

We analyze export data aggregated at world global level of 219 classes of products over a period of 39 years. Our main goal is to set up a dynamical model to identify and quantify plausible mechanisms by which the evolutions of the various…

Economics · Quantitative Finance 2016-09-20 Michele Caraglio , Fulvio Baldovin , Attilio L. Stella

Various variants of the well known Covariance Matrix Adaptation Evolution Strategy (CMA-ES) have been proposed recently, which improve the empirical performance of the original algorithm by structural modifications. However, in practice it…

Neural and Evolutionary Computing · Computer Science 2018-08-20 Sander van Rijn , Hao Wang , Matthijs van Leeuwen , Thomas Bäck

The environment in which a population evolves can have a crucial impact on selection. We study evolutionary dynamics in finite populations of fixed size in a changing environment. The population dynamics are driven by birth and death…

Populations and Evolution · Quantitative Biology 2014-09-01 Peter Ashcroft , Philipp M Altrock , Tobias Galla

One of the fundamental problems in biology concerns the method by which a cluster of organisms can regulate the proportion of individuals that perform various roles or modes as if each individual knows a whole situation without a leader. A…

Adaptation and Self-Organizing Systems · Physics 2015-12-21 Mayuko Iwamoto , Daishin Ueyama

A model of pattern formation in living systems is presented. The pattern is achieved by the sequential interaction of two signaling pathways. The coupling of the pattern to the (thick) epithelial sheet changes is given, when the Gauss…

Tissues and Organs · Quantitative Biology 2009-05-11 Frederick W. Cummings

Reputation plays a crucial role in social interactions by affecting the fitness of individuals during an evolutionary process. Previous works have extensively studied the result of imitation dynamics without focusing on potential irrational…

Physics and Society · Physics 2024-04-24 Kehuan Feng , Songlin Han , Minyu Feng , Attila Szolnoki

A biologically motivated model for spatio-temporal coexistence of two competing species is studied by mean-field theory and numerical simulations. In d>1 dimensions the phase diagram displays an extended region where both species coexist,…

Statistical Mechanics · Physics 2007-05-23 Heiko Reinhardt , Frank Boehm , Barbara Drossel , Haye Hinrichsen