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In this paper we propose a systematic approach to construct mathematical models describing populations of cancer-cells at different stages of disease development. The methodology we propose is based on stochastic Concurrent Constraint…

Computational Engineering, Finance, and Science · Computer Science 2011-09-08 Luca Bortolussi , Alberto Policriti

Stochastic motion of a point -- known as Brownian motion -- has many successful applications in science, thanks to its scale invariance and consequent universal features such as Gaussian fluctuations. In contrast, the stochastic motion of a…

Statistical Mechanics · Physics 2011-08-11 Kazumasa A. Takeuchi , Masaki Sano , Tomohiro Sasamoto , Herbert Spohn

In biophysics, the search for analytical solutions of stochastic models of cellular processes is often a challenging task. In recent work on models of gene expression, it was shown that a mapping based on partitioning of Poisson arrivals…

Biological Physics · Physics 2018-05-09 Hugo Tschirhart , Thierry Platini

Cellular Automata are discrete-time dynamical systems on a spatially extended discrete space which provide paradigmatic examples of nonlinear phenomena. Their stochastic generalizations, i.e., Probabilistic Cellular Automata (PCA), are…

Statistical Mechanics · Physics 2015-06-16 Emilio N. M. Cirillo , P. -Y. Louis , W. M. Ruszel , C. Spitoni

Three models from statistical physics can be analyzed by employing space-time determinantal processes: (1) crystal facets, in particular the statistical properties of the facet edge, and equivalently tilings of the plane, (2)…

Statistical Mechanics · Physics 2009-11-11 Herbert Spohn

The properties of a wide variety of growing models, generically called $X/RD$, are studied by means of numerical simulations and analytic developments. The study comprises the following $X$ models: Ballistic Deposition, Random Deposition…

Statistical Mechanics · Physics 2009-11-11 Claudio M. Horowitz , Ezequiel V. Albano

Many complex systems occurring in the natural or social sciences or economics are frequently described on a microscopic level, e.g., by lattice- or agent-based models. To analyze the states of such systems and their bifurcation structure on…

Adaptation and Self-Organizing Systems · Physics 2020-10-07 Clemens Willers , Uwe Thiele , Andrew J. Archer , David J. B. Lloyd , Oliver Kamps

The dynamics of a one dimensional growth model involving attachment and detachment of particles is studied in the presence of a localized growth inhomogeneity along with anchored boundary conditions. At large times, the latter enforce an…

Statistical Mechanics · Physics 2007-05-23 M. D. Grynberg

We take up the challenge of designing realistic computational models of large interacting cell populations. The goal is essentially to bring Gillespie's celebrated stochastic methodology to the level of an interacting population of cells.…

Computational Engineering, Finance, and Science · Computer Science 2018-10-26 Stefan Engblom

The proposed stochastic model for pedestrian dynamics is based on existing approaches using cellular automata, combined with substantial extensions, to compensate the deficiencies resulting of the discrete grid structure. This agent motion…

Physics and Society · Physics 2021-04-01 Michael Schultz

The dynamical processes taking place on a network depend on its topology. Influencing the growth process of a network therefore has important implications on such dynamical processes. We formulate the problem of influencing the growth of a…

Social and Information Networks · Computer Science 2016-12-28 Dominik Thalmeier , Vicenç Gómez , Hilbert J. Kappen

We present results from an experiment similar to one performed by Packard (1988), in which a genetic algorithm is used to evolve cellular automata (CA) to perform a particular computational task. Packard examined the frequency of evolved CA…

adap-org · Physics 2008-02-03 Melanie Mitchell , Peter Hraber , James P. Crutchfield

For stationary interface growth, governed by the Kardar-Parisi-Zhang (KPZ) equation in 1 + 1 dimensions, typical fluctuations of the interface height at long times are described by the Baik-Rains distribution. Recently Chhita et al. [1]…

Statistical Mechanics · Physics 2017-11-22 Baruch Meerson , Johannes Schmidt

Cellular automata (CA) is an important modelling paradigm for complex systems. In the design of cellular automata, the most difficult task is to find the transformation rules that describe the temporal evolution or pattern of a modelled…

Cellular Automata and Lattice Gases · Physics 2023-10-03 Lei Kou , Fangfang Zhang , Luobing Chen , Wende Ke , Quande Yuan , Junhe Wan , Zhen Wang

When a growing interface belonging to the KPZ universality class is tilted with average slope $m$, its average velocity increases in $\frac{\Lambda}{2}\,m^2$, where $\Lambda$ is related to the nonlinear coefficient $\lambda$ of the KPZ…

Statistical Mechanics · Physics 2021-06-11 M. F. Torres , R. C. Buceta

Stochastic modelling provides an indispensable tool for understanding how random events at the molecular level influence cellular functions. In practice, the common challenge is to calibrate a large number of model parameters against the…

Molecular Networks · Quantitative Biology 2015-03-17 Shuohao Liao , Tomas Vejchodsky , Radek Erban

Classical Cellular Automata (CCAs) are a powerful computational framework for modeling global spatio-temporal dynamics with local interactions. While CCAs have been applied across numerous scientific fields, identifying the local rule that…

Systems and Control · Electrical Eng. & Systems 2025-07-01 Faizal Hafiz , Amelia Kunze , Enrico Formenti , Davide La Torre

A simulation approach to the stochastic growth of bacterial towers is presented, in which a non-uniform and finite nutrient supply essentially determines the emerging structure through elementary chemotaxis. The method is based on cellular…

Populations and Evolution · Quantitative Biology 2009-11-10 J. O. Indekeu , C. V. Giuraniuc

We investigate a class of Young diagrams growing via the addition of unit cells and satisfying the constraint that the height difference between adjacent columns $\geq r$. In the long time limit, appropriately re-scaled Young diagrams…

Statistical Mechanics · Physics 2021-06-09 P. L. Krapivsky

Widely used closed product-form networks have emerged recently as a primary model of stochastic growth of sub-cellular structures, e.g., cellular filaments. In the baseline model, homogeneous monomers attach and detach stochastically to…

Probability · Mathematics 2020-07-30 Predrag Jelenkovic , Jane Kondev , Lishibanya Mohapatra , Petar Momcilovic