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Protein aggregation on the plasma membrane (PM) is of critical importance to many cellular processes such as cell adhesion, endocytosis, fibrillar conformation, and vesicle transport. Lateral diffusion of protein aggregates or clusters on…

Subcellular Processes · Quantitative Biology 2019-08-15 L. M. Stolerman , M. Getz , S. G. Llewellyn Smith , M. Holst , P. Rangamani

Every mathematical model describing physical phenomena is an approximation to model reality, hence has its limitations. Depending on characteristic values of the variables in the model, different aspects of the model and, e.g.,…

Analysis of PDEs · Mathematics 2019-12-02 Björn Augner , Dieter Bothe

Describing particle transport at the macroscopic or mesoscopic level in non-ideal environments poses fundamental theoretical challenges in domains ranging from inter and intra-cellular transport in biology to diffusion in porous media. Yet,…

Statistical Mechanics · Physics 2013-09-11 Marta Galanti , Duccio Fanelli , Francesco Piazza

We propose a data-driven framework to learn interaction kernels in stochastic multi-agent systems. Our approach aims at identifying the functional form of nonlocal interaction and diffusion terms directly from trajectory data, without any a…

Machine Learning · Computer Science 2026-03-18 Giacomo Albi , Alessandro Alla , Elisa Calzola

We have theoretically studied the uptake of a non-uniformly charged biomolecule, suitable to represent a globular protein or a drug, by a charged hydrogel carrier in the presence of a 1:1 electrolyte. Based on the analysis of a physical…

Soft Condensed Matter · Physics 2017-04-26 Irene Adroher-Benitez , Arturo Moncho-Jorda , Joachim Dzubiella

Reaction-diffusion models with nonlocal constraints naturally arise as limiting cases of coupled bulk-surface models of intracellular signalling. In this paper, a minimal, mass-conserving model of cell-polarization on a curved membrane is…

Pattern Formation and Solitons · Physics 2022-10-04 Pearson W. Miller , Daniel Fortunato , Matteo Novaga , Stanislav Y. Shvartsman , Cyrill B. Muratov

The transport of individual entities through interconnected structures is a process of practical relevance both in biology and technology. Examples are given by diffusive dynamics of molecules in porous structures. In soft environments,…

Soft Condensed Matter · Physics 2026-02-09 Jakob Mihatsch , Andreas M. Menzel

We consider aspects of the population dynamics, inside a bound domain, of diffusing agents carrying an attribute which is stochastically destroyed upon contact with the boundary. The normal mode analysis of the relevant Helmholtz equation…

Soft Condensed Matter · Physics 2015-05-13 Seungoh Ryu

In 1977 Berg & Purcell published a landmark paper entitled "Physics of Chemoreception" which examined how a bacterium can sense a chemical attractant in the fluid surrounding it. At small scales the attractant molecules move by Brownian…

Analysis of PDEs · Mathematics 2017-07-18 Andrew J. Bernoff , Alan E. Lindsay

The contact process is a stochastic process which exhibits a continuous, absorbing-state phase transition in the Directed Percolation (DP) universality class. In this work, we consider a contact process with a bias in conjunction with an…

Statistical Mechanics · Physics 2013-05-20 A. Costa , R. A. Blythe , M. R. Evans

Cytoskeletal motor proteins are involved in major intracellular transport processes which are vital for maintaining appropriate cellular function. The motor exhibits distinct states of motility: active motion along filaments, and…

Biological Physics · Physics 2016-11-29 Anne E. Hafner , Ludger Santen , Heiko Rieger , M. Reza Shaebani

The evolution of particulate and multiphase systems can transition from dynamic regimes, governed by classical transport equations with well-defined damping coefficients, to anomalously slow relaxation described by rate equations when the…

Soft Condensed Matter · Physics 2025-08-20 Carlos E. Colosqui

Liquid-liquid phase separation plays a major role in the formation and maintenance of various membrane-less subcellular structures in the cytoplasm and nucleus of cells. Biological condensates contain enhanced concentrations of proteins and…

Soft Condensed Matter · Physics 2023-10-03 Paul C Bressloff

We consider single-file diffusion in an open system with two species $A,B$ of particles. At the boundaries we assume different reservoir densities which drive the system into a non-equilibrium steady state. As a model we use an…

Statistical Mechanics · Physics 2007-05-23 A. Brzank , G. M. Schütz

In this work we study a kinetic model of active particles with delayed dynamics, and its limit when the number of particles goes to infinity. This limit turns out to be related to delayed differential equations with random initial…

Analysis of PDEs · Mathematics 2020-06-17 Juan Pablo Pinasco , Mauro Rodriguez Cartabia , Nicolas Saintier

Diffusion describes the motion of microscopic entities from regions of high concentration to regions of low concentration. In multiplex networks, flows can occur both within and across layers, and super-diffusion, a regime where the time…

Physics and Society · Physics 2019-04-02 Giulia Cencetti , Federico Battiston

Random sequential adsorption (RSA) models have been studied due to their relevance to deposition processes on surfaces. The depositing particles are represented by hard-core extended objects; they are not allowed to overlap. Numerical Monte…

Condensed Matter · Physics 2016-07-12 P. Nielaba , V. Privman , J. -S. Wang

Kinetics of model catalytic processes proceeding on inhomogeneous surfaces is studied. We employ an extended mean-field model that takes into account surface inhomogeneities. The influence of surface diffusion of adsorbent on the kinetics…

Materials Science · Physics 2009-11-13 Lukasz Cwiklik

Computational identification of unknown adsorption and desorption rates is discussed in conjunction with reactive flow considered at pore scale. The reactive transport is governed by incompressible Stokes equations, coupled with…

Numerical Analysis · Mathematics 2019-12-10 Vasiliy V. Grigoriev , Oleg Iliev , Petr N. Vabishchevich

We examine the phase space structures that govern reaction dynamics in the absence of critical points on the potential energy surface. We show that in the vicinity of hyperbolic invariant tori it is possible to define phase space dividing…