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Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the formalism of Boolean dynamical networks, analyzing the…

Molecular Networks · Quantitative Biology 2021-09-13 Enrico Borriello , Bryan C. Daniels

There has been a long debate on how new levels of organization have evolved. It might seem unlikely, as cooperation must prevail over competition. One well-studied example is the emergence of autocatalytic sets, which seem to be a…

Populations and Evolution · Quantitative Biology 2026-02-16 Sean P. Maley , Carlos Gershenson , Stuart A. Kauffman

It is well-known that population structure is a catalyst for the evolution of cooperation since individuals can reciprocate with their neighbors through local interactions defined by network structures. Previous research typically relies on…

Physics and Society · Physics 2021-12-16 Anzhi Sheng , Aming Li , Long Wang

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2008-01-30 Winfried Just , German Enciso

We present a general model for the growth of weighted networks in which the structural growth is coupled with the edges' weight dynamical evolution. The model is based on a simple weight-driven dynamics and a weights' reinforcement…

Statistical Mechanics · Physics 2009-11-10 Alain Barrat , Marc Barthelemy , Alessandro Vespignani

We study the emergence of coherence in complex networks of mutually coupled non-identical elements. We uncover the precise dependence of the dynamical coherence on the network connectivity, on the isolated dynamics of the elements and the…

Adaptation and Self-Organizing Systems · Physics 2013-08-09 Tiago Pereira , Deniz Eroglu , G. B. Bagci , U. Tirnakli , Henrik J. Jensen

We study expanding circle maps interacting in a heterogeneous random network. Heterogeneity means that some nodes in the network are massively connected, while the remaining nodes are only poorly connected. We provide a probabilistic…

Dynamical Systems · Mathematics 2013-08-27 Tiago Pereira , Sebastian van Strien , Jeroen S. W. Lamb

In spite of its relevance to the origin of complex networks, the interplay between form and function and its role during network formation remains largely unexplored. While recent studies introduce dynamics by considering rewiring processes…

Physics and Society · Physics 2008-07-18 J. Poncela , J. Gomez-Gardenes , L. M. Floria , A. Sanchez , Y. Moreno

Genetic regulatory networks are defined by their topology and by a multitude of continuously adjustable parameters. Here we present a class of simple models within which the relative importance of topology vs. interaction strengths becomes…

Molecular Networks · Quantitative Biology 2013-08-02 Mikhail Tikhonov , William Bialek

The co-evolution of structure and dynamics, known as adaptivity, is a fundamental property in various systems and drives diverse emergent behaviors. However, the adaptivity in previous works is primarily stemmed from pairwise situations,…

Physics and Society · Physics 2025-08-22 Longzhao Liu , Hongwei Zheng , Zhihao Han , Xin Wang , Shaoting Tang

Complex networks describe a wide range of systems in nature and society, much quoted examples including the cell, a network of chemicals linked by chemical reactions, or the Internet, a network of routers and computers connected by physical…

Statistical Mechanics · Physics 2016-08-31 Reka Albert , Albert-Laszlo Barabasi

Most models of complex systems have been homogeneous, i.e., all elements have the same properties (spatial, temporal, structural, functional). However, most natural systems are heterogeneous: few elements are more relevant, larger,…

Adaptation and Self-Organizing Systems · Physics 2025-12-22 Amahury Jafet López-Díaz , Fernanda Sánchez-Puig , Carlos Gershenson

Boolean networks, widely used to model gene regulation, exhibit a phase transition between regimes in which small perturbations either die out or grow exponentially. We show and numerically verify that this phase transition in the dynamics…

Statistical Mechanics · Physics 2013-05-30 Shane Squires , Edward Ott , Michelle Girvan

Boolean networks have been successfully used in modelling gene regulatory networks. In this paper we propose a reduction method that reduces the complexity of a Boolean network but keeps dynamical properties and topological features and…

Quantitative Methods · Quantitative Biology 2009-07-06 Alan Veliz-Cuba

As one of the main subjects of investigation in data science, network science has been demonstrated a wide range of applications to real-world networks analysis and modeling. For example, the pervasive presence of structural or topological…

Logic in Computer Science · Computer Science 2020-09-28 Felipe S. Abrahão , Klaus Wehmuth , Artur Ziviani

The dynamics of noise-resilient Boolean networks with majority functions and diverse topologies is investigated. A wide class of possible topological configurations is parametrized as a stochastic blockmodel. For this class of networks, the…

Disordered Systems and Neural Networks · Physics 2012-01-11 Tiago P. Peixoto

We study the problem of computing a minimal subset of nodes of a given asynchronous Boolean network that need to be controlled to drive its dynamics from an initial steady state (or attractor) to a target steady state. Due to the phenomenon…

Systems and Control · Computer Science 2018-05-18 Soumya Paul , Cui Su , Jun Pang , Andrzej Mizera

We present a rigorous mathematical framework for analyzing dynamics of a broad class of Boolean network models. We use this framework to provide the first formal proof of many of the standard critical transition results in Boolean network…

Disordered Systems and Neural Networks · Physics 2016-08-30 C. Seshadhri , Yevgeniy Vorobeychik , Jackson R. Mayo , Robert C. Armstrong , Joseph R. Ruthruff

The concept of (auto)catalytic systems has become a cornerstone in understanding evolutionary processes in various fields. The common ground is the observation that for the production of new species/goods/ideas/elements etc. the…

Populations and Evolution · Quantitative Biology 2009-11-13 Rudolf Hanel , Peter Klimek , Stefan Thurner

Random Boolean networks (RBNs) are frequently employed for modelling complex systems driven by information processing, e.g. for gene regulatory networks (GRNs). Here we propose a hierarchical adaptive RBN (HARBN) as a system consisting of…

Physics and Society · Physics 2016-03-23 Piotr J. Gorski , Agnieszka Czaplicka , Janusz A. Holyst