English
Related papers

Related papers: Single Molecule Michaelis-Menten Equation beyond Q…

200 papers

In this work we study a kinetic model of active particles with delayed dynamics, and its limit when the number of particles goes to infinity. This limit turns out to be related to delayed differential equations with random initial…

Analysis of PDEs · Mathematics 2020-06-17 Juan Pablo Pinasco , Mauro Rodriguez Cartabia , Nicolas Saintier

Single-enzyme catalysis offers a promising approach for unravelling the dynamic behaviour of individual enzymes as they undergo a reaction, revealing the complex heterogeneity that is lost in the averaged ensembles. Here we demonstrate…

By combining methods of kinetic and density functional theory, we present a description of molecular fluids which accounts for their microscopic structure and thermodynamic properties as well as for the hydrodynamic behavior. We focus on…

Mesoscale and Nanoscale Physics · Physics 2015-05-18 Umberto Marini Bettolo Marconi , Simone Melchionna

To analyze possible generalizations of reaction-diffusion schemes for the case of subdiffusion we discuss a simple monomolecular conversion A --> B. We derive the corresponding kinetic equations for local A and B concentrations. Their form…

Statistical Mechanics · Physics 2009-11-11 I. M. Sokolov , M. G. W. Schmidt , F. Sagues

Photo-luminescence intermittency (blinking) in semiconductor nanocrystals (NCs), a phenomenon ubiquitous to single-emitters, is generally considered to be temporally random intensity fluctuations between bright (On) and dark (Off) states.…

Mesoscale and Nanoscale Physics · Physics 2020-01-29 Amitrajit Mukherjee , Korak Kumar Ray , Chinmay Phadnis , Arunasish Layek , Soumya Bera , Arindam Chowdhury

In this study, through phenomenological comparison of the velocity-force data of processive motor proteins, including conventional kinesin, cytoplasmic dynein and myosin V, we found that, the ratio between motor velocities of two different…

Biological Physics · Physics 2015-05-30 Yunxin Zhang

Low-dimensional, complex systems are often characterized by logarithmically slow dynamics. We study the generic motion of a labeled particle in an ensemble of identical diffusing particles with hardcore interactions in a strongly…

Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

Several different enzymes display an apparent diffusion coefficient that increases with the concentration of their substrate. Moreover, their motion becomes directed in substrate gradients. Currently, there are several competing models for…

Biological Physics · Physics 2020-09-23 Giovanni Giunta , Hamid Seyed-Allaei , Ulrich Gerland

The equations of fluctuating nonlinear hydrodynamics for a two component mixture are obtained with a proper choice of slow variables which correspond to the conservation laws in the system. Using these nonlinear equations we construct the…

Statistical Mechanics · Physics 2016-01-20 Madhu Priya , Neeta Bidhoodi , Shankar P. Das

The rates of chemical reactions are not absolute but their magnitude depends upon the relative speeds of the moving observers. This has been proved by unifying theories of chemical kinetics, which are transition state theory, collision…

General Physics · Physics 2017-06-13 Mirza Wasif Baig

Single molecule time traces reveal the time evolution of unsynchronized kinetic systems. Especially single molecule F\"orster resonance energy transfer (smFRET) provides access to enzymatically important timescales, combined with molecular…

Quantitative Methods · Quantitative Biology 2018-01-17 Sonja Schmid , Thorsten Hugel

In this paper we prove that the well-known quasi-steady state approximations, commonly used in enzyme kinetics, which can be interpreted as the reduced system of a differential system depending on a perturbative parameter, according to…

Dynamical Systems · Mathematics 2017-02-20 Alberto Maria Bersani , Enrico Bersani , Alessandro Borri , Pierluigi Vellucci

We consider a general class of autocatalytic reactions, that has been shown to display stochastically switching behaviour (Discreteness Induced Transitions) in some parameter regimes. This behaviour was shown to occur when either the…

Probability · Mathematics 2023-12-01 Cameron Gallinger , Lea Popovic

Enzymes show two distinct transport behaviors in the presence of their substrates in solution. First, their diffusivity enhances with increasing substrate concentration. In addition, enzymes perform directional motion toward regions with…

Biological Physics · Physics 2018-11-06 Farzad Mohajerani , Xi Zhao , Ambika Somasundar , Darrell Velegol , Ayusman Sen

We consider the singular limit of a chemotaxis model of bacterial collective motion recently introduced in arXiv:2009.11048 [math.AP]. The equation models aggregation-diffusion phenomena with advection that is discontinuous and depends…

Analysis of PDEs · Mathematics 2025-08-28 Maria Gualdani , Mikel Ispizua , Nicola Zamponi

Systems composed of large numbers of interacting agents often admit an effective coarse-grained description in terms of a multidimensional stochastic dynamical system, driven by small-amplitude intrinsic noise. In applications to…

Probability · Mathematics 2017-03-30 Todd L. Parsons , Tim Rogers

Chemical master equation plays an important role to describe the time evolution of homogeneous chemical system. In addition to the reaction process, it is also accompanied by physical diffusion of the reactants in complex system that is…

Chemical Physics · Physics 2025-03-06 Hong Zhang , Guohua Li

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

Analysis of PDEs · Mathematics 2026-01-07 Romina Travaglini , João Miguel Oliveira