English
Related papers

Related papers: Enhancing protein drop stability for crystallizati…

200 papers

Theories of protein crystallization based on spheres that form close-packed crystals predict optimal assembly within a `slot' of second virial coefficients and enhanced assembly near the metastable liquid-vapor critical point. However, most…

Soft Condensed Matter · Physics 2014-04-04 Thomas K. Haxton , Stephen Whitelam

Crystallization and vitrification are two different routes to form a solid. Normally these two processes suppress each other, with the glass transition preventing crystallization at high density (or low temperature). This is even true for…

Soft Condensed Matter · Physics 2014-08-26 Ran Ni , Martien A. Cohen Stuart , Marjolein Dijkstra , Peter G. Bolhuis

Pinning and depinning of drops on an inclined heterogeneous substrate is studied as a function of the inclination and heterogeneity amplitude. Two types of heterogeneity are considered: a hydrophobic defect that blocks the droplet in front,…

Fluid Dynamics · Physics 2013-03-25 Uwe Thiele , Edgar Knobloch

The stretching of viscoelastic polymer solutions close to break-up can create attached drops on a filament, whose properties and dynamics are little understood. The stretching of capillary bridges and the consecutive filament, until its…

Soft Condensed Matter · Physics 2025-05-13 Hrishikesh Pingulkar , Jorge Peixinho , Olivier Crumeyrolle

Identifying the conditions under which glass formation occurs is crucial for a fundamental understanding of the glass transition mechanism. Pure liquids devoid of any frustration avoid glass transition and undergo crystallization. In this…

Soft Condensed Matter · Physics 2026-03-04 Saumya Suvarna , Prabhat K. Jaiswal , Madhu Priya

We study the evolution from a liquid to a crystal phase in two-dimensional curved space. At early times, while crystal seeds grow preferentially in regions of low curvature, the lattice frustration produced in regions with high curvature is…

Soft Condensed Matter · Physics 2015-06-16 Nicolas A. Garcia , Richard A. Register , Daniel A. Vega , Leopoldo R. Gomez

We performed dynamic simulations of spheres with short-range attractive interactions for many values of interaction strength and range. Fast crystallization occurs in a localized region of this parameter space, but the character of…

Soft Condensed Matter · Physics 2015-07-27 Thomas K. Haxton , Lester O. Hedges , Stephen Whitelam

Enhancing the kinetic stability of glasses often necessitates deepening thermodynamic stability, which typically compromises ductility due to increased structural rigidity. Decoupling these properties remains a critical challenge for…

Materials Science · Physics 2025-12-24 Huanrong Liu , Qingan Li , Shan Zhang , Rui Su , Yunjiang Wang , Pengfei Guan

We study theoretically the hydrodynamics of a fluid drop containing oriented filaments endowed with active contractile or extensile stresses and placed on a solid surface. The active stresses alter qualitatively the wetting properties of…

Soft Condensed Matter · Physics 2015-06-03 Jean-Francois Joanny , Sriram Ramaswamy

We report on new instabilities of the quasi-static equilibrium of water drops pinned by a hydrophobic inclined substrate. The contact line of a statically pinned drop exhibits three transitions of partial depinning: depinning of the…

Fluid Dynamics · Physics 2009-11-13 Viatcheslav V. Berejnov , Robert E. Thorne

There are large number of proteins, the existence of which are known but not their crystal structure, because of difficulty in finding the exact condition for their crystallization. Heterogeneous nucleation on disordered porous substrates…

Biological Physics · Physics 2015-10-19 Anindita Sengupta Ghatak , Animangsu Ghatak

Substrate defects crucially influence the onset of sliding drop motion under lateral driving. A finite force is necessary to overcome the pinning influence even of microscale heterogeneities. The depinning dynamics of three-dimensional…

Fluid Dynamics · Physics 2013-03-25 Ph. Beltrame , P. Hänggi , U. Thiele

We investigate the dynamics of micron-scale drops pushed across a hydrophobic or superhydrophobic surface. The velocity profile across the drop varies from quadratic to linear with increasing height, indicating a crossover from a sliding to…

Soft Condensed Matter · Physics 2010-09-24 B. M. Mognetti , H. Kusumaatmaja , J. M. Yeomans

Fluid convection during protein crystallization plays a significant role in determining crystal growth rate and crystal quality. Crystals grown in reduced flow strength gives better quality crystal. Hence, tuning the flow strength is very…

Soft Condensed Matter · Physics 2020-03-23 Tapan Kumar Pradhan , Pradipta Kumar Panigrahi

It has been shown that a water drop can bounce persistently, when thrown on a super-hydrophobic substrate. We present here scaling arguments which allow us to predict the maximal deformation and the contact time of the drop. This approach…

Soft Condensed Matter · Physics 2009-11-07 K. Okumura , F. Chevy , C. Clanet , D. Richard , D. Quere

We present systematic wetting experiments and numerical simulations of gravity driven liquid drops sliding on a plane substrate decorated with a linear chemical step. Surprisingly, the optimal direction to observe crossing is not the one…

Molecular dynamics simulations are used to investigate strain localization in a model nanocrystalline metal. The atomic mechanisms of such catastrophic failure are first studied for two grain sizes of interest. Detailed analysis shows that…

Materials Science · Physics 2014-08-26 Timothy J. Rupert

Liquid droplets usually wet smooth and homogeneous substrates isotropically. Recent research works have revealed that droplets sit, slide and spread anisotropically on uniaxially stretched soft substrates, showing an enhanced wettability…

Soft Condensed Matter · Physics 2022-12-02 Yixuan Du , Elmar Bonaccurso , Jianwei Guo , Kai Uhlig , Longquan Chen , Binyu Zhao , Günter K. Auernhammer

Anisotropically wetting substrates enable useful control of droplet behavior across a range of applications. Usually, these involve chemically or physically patterning the substrate surface, or applying gradients in properties like…

Soft Condensed Matter · Physics 2021-04-21 Katrina Smith-Mannschott , Qin Xu , Stefanie Heyden , Nicolas Bain , Eric R. Dufresne , Robert W. Style

Functional proteins must fold with some minimal stability to a structure that can perform a biochemical task. Here we use a simple model to investigate the relationship between the stability requirement and the capacity of a protein to…

Biomolecules · Quantitative Biology 2009-11-10 Jesse D Bloom , Claus O Wilke , Frances H Arnold , Christoph Adami