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Self-assembly is the autonomous organization of components into patterns or structures: an essential ingredient of biology and a desired route to complex organization. At equilibrium, the structure is encoded through specific interactions,…

Soft Condensed Matter · Physics 2018-10-03 Antoine Aubret , Mena Youssef , Stefano Sacanna , Jérémie Palacci

Like the letters in the alphabet forming words, reusing components of a heterogeneous mixture is an efficient strategy for assembling a large number of target structures. Examples range from synthetic DNA origami to proteins self-assembling…

Statistical Mechanics · Physics 2024-12-10 Félix Benoist , Pablo Sartori

We use computer simulations to investigate self-assembly in a system of model chaperonin proteins, and in an Ising lattice gas. We discuss the mechanisms responsible for rapid and efficient assembly in these systems, and we use measurements…

Soft Condensed Matter · Physics 2011-12-09 James Grant , Robert L. Jack , Stephen Whitelam

Using large deviation theory and principles of stochastic optimal control, we show that rare molecular dynamics trajectories conditioned on assembling a specific target structure encode a set of interactions and external forces that lead to…

Soft Condensed Matter · Physics 2021-01-14 Avishek Das , David T. Limmer

The field of complex self-assembly is moving toward the design of multi-particle structures consisting of thousands of distinct building blocks. To exploit the potential benefits of structures with such `addressable complexity,' we need to…

Soft Condensed Matter · Physics 2015-06-02 William M. Jacobs , Aleks Reinhardt , Daan Frenkel

Using a recently introduced formulation of the ground-state inverse design problem for a targeted lattice [Pi\~neros et al., J. Chem. Phys. 144} 084502 (2016)], we discover purely repulsive and isotropic pair interactions that stabilize…

Soft Condensed Matter · Physics 2018-01-10 William D. Piñeros , Thomas M. Truskett

The self assembly of core-corona discs interacting via anisotropic potentials is investigated using Monte Carlo computer simulations. A minimal interaction potential that incorporates anisotropy in a simple way is introduced. It consists in…

Soft Condensed Matter · Physics 2012-01-27 Daniel Salgado-Blanco , Carlos I. Mendoza

Manipulating the way in which colloidal particles self-organise is a central challenge in the design of functional soft materials. Meeting this challenge requires the use of building blocks that interact with one another in a highly…

Soft Condensed Matter · Physics 2021-03-30 Joe G Donaldson , Peter Schall , Laura Rossi

A binary mixture of particles interacting with spherically-symmetric potentials leading to microsegregation is studied by theory and molecular dynamics (MD) simulations. We consider spherical particles with equal diameters and volume…

Soft Condensed Matter · Physics 2020-11-20 O. Patsahan , M. Litniewski , A. Ciach

Studying evolutionary correlations in alignments of homologous sequences by means of an inverse Potts model has proven useful to obtain residue-residue contact energies and to predict contacts in proteins. The quality of the results depend…

Biomolecules · Quantitative Biology 2019-09-04 G. Franco , M. Cagiada , G. Bussi , G. Tiana

Force matching is an established technique to generate effective potentials for molecular dynamics simulations from first-principles data. This method has been implemented in the open source code potfit. Here, we present a review of the…

Autonomous materials discovery with desired properties is one of the ultimate goals for materials science, and the current studies have been focusing mostly on high-throughput screening based on density functional theory calculations and…

Accurate interaction potentials between microscopic components such as colloidal particles or cells are crucial to understanding a range of processes, including colloidal crystallization, bacterial colony formation, and cancer metastasis.…

Nano- to micro-sized particles with differently charged surface areas exhibit complex interaction patterns, characterized by both opposite-charge attraction and like-charge repulsion. While several successful models have been proposed in…

Soft Condensed Matter · Physics 2025-01-16 Daniele Notarmuzi , Silvano Ferrari , Emanuele Locatelli , Emanuela Bianchi

Irreversible random sequential deposition of interacting particles is widely used to model aggregation phenomena in physical, chemical, and biophysical systems. We show that in one dimension the exact time dependent solution of such…

Statistical Mechanics · Physics 2019-06-07 Adrian Baule

We propose a method to tune interactions between absorptionless colloidal particle pairs. This is achieved via optimization of the spectral energy density of a homogeneous random optical field. Several standard and more exotic interaction…

Soft Condensed Matter · Physics 2025-10-09 Augustin Muster , Diego Romero Abujetas , Frank Scheffold , Luis S. Froufe-Pérez

The ability to rapidly manufacture building blocks with specific binding interactions is a key aspect of programmable assembly. Recent developments in DNA nanotechnology and colloidal particle synthesis have significantly advanced our…

Soft Condensed Matter · Physics 2024-03-06 Chrisy Xiyu Du , Hanyu Alice Zhang , Tanner Pearson , Jakin Ng , Paul McEuen , Itai Cohen , Michael P. Brenner

Self-assembly is one of the prevalent strategies used by living systems to fabricate ensembles of precision nanometer-scale structures and devices. The push for analogous approaches to create synthetic nanomaterials has led to the…

Patchy particles have proven to be a prominent model for studying the self-assembly behavior of various systems, ranging from finite clusters to bulk crystal assemblies, and from synthetic colloidal particles to viruses. The patchy particle…

Soft Condensed Matter · Physics 2025-10-13 Gregory Snyder , Chrisy Xiyu Du

We introduce a method for solving the "inverse" phase equilibria problem: How should the interactions among a collection of molecular species be designed in order to achieve a target phase diagram? Using techniques from convex optimization…

Soft Condensed Matter · Physics 2023-06-06 Fan Chen , William M. Jacobs
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