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We consider the statistics of the areas enclosed by domain boundaries (`hulls') during the curvature-driven coarsening dynamics of a two-dimensional nonconserved scalar field from a disordered initial state. We show that the number of hulls…

Statistical Mechanics · Physics 2007-06-13 Jeferson J. Arenzon , Alan J. Bray , Leticia F. Cugliandolo , Alberto Sicilia

Active motions of a biological membrane can be induced by non-thermal fluctuations that occur in the outer environment of the membrane. We discuss the dynamics of a membrane interacting hydrodynamically with an active wall that exerts…

Soft Condensed Matter · Physics 2016-05-18 Kento Yasuda , Shigeyuki Komura , Ryuichi Okamoto

The formation of microdomains, also called rafts, in biomembranes can be attributed to the surface tension of the membrane. In order to model this phenomenon, a model involving a coupling between the local composition and the local…

Analysis of PDEs · Mathematics 2016-06-29 Irene Fonseca , Gurgen Hayrapetyan , Giovanni Leoni , Barbara Zwicknagl

Proteins and nucleic acids can spontaneously self-assemble into membraneless droplet-like compartments, both in vitro and in vivo. A key component of these droplets are multi-valent proteins that possess several adhesive domains with…

Biomolecules · Quantitative Biology 2020-01-10 Srivastav Ranganathan , Eugene Shakhnovich

We provide a comprehensive view of various phase transitions in random $K$-satisfiability problems solved by stochastic-local-search algorithms. In particular, we focus on the finite-size scaling (FSS) exponent, which is mathematically…

Statistical Mechanics · Physics 2015-03-17 Sang Hoon Lee , Meesoon Ha , Chanil Jeon , Hawoong Jeong

We use a modified Shan-Chen, noiseless lattice-BGK model for binary immiscible, incompressible, athermal fluids in three dimensions to simulate the coarsening of domains following a deep quench below the spinodal point from a symmetric and…

Soft Condensed Matter · Physics 2009-11-10 Nélido González-Segredo , Maziar Nekovee , Peter V. Coveney

Motivated by experimental observations of patterning at the leading edge of motile eukaryotic cells, we introduce a general model for the dynamics of nearly-flat fluid membranes driven from within by an ensemble of activators. We include,…

Statistical Mechanics · Physics 2022-02-09 Francesco Cagnetta , Viktor Skultety , Martin R. Evans , Davide Marenduzzo

Multicomponent lipid mixtures exhibit complex phase behavior, including coexistence of nanoscopic fluid phases in ternary mixtures mimicking the composition of the outer leaflet of mammalian plasma membrane. The physical mechanisms…

Soft Condensed Matter · Physics 2011-06-01 Frederick A. Heberle , Gerald W. Feigenson

The finite-size effects prominent in zero-range processes exhibiting a condensation transition are studied by using continuous-time Monte Carlo simulations. We observe that, well above the thermodynamic critical point, both static and…

Statistical Mechanics · Physics 2010-09-21 Janne Juntunen , Otto Pulkkinen , Juha Merikoski

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

Conservative and non-conservative phase-field models are considered for the numerical simulation of lateral phase separation and coarsening in biological membranes. An unfitted finite element method is devised for these models to allow for…

Numerical Analysis · Mathematics 2019-01-08 Vladimir Yushutin , Annalisa Quaini , Sheereen Majd , Maxim Olshanskii

Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg

We study, by means of mean field calculations and Monte Carlo simulations of a lattice-gas model, the distribution of adhesion sites of a bilayer membrane and a supporting flat surface. Our model accounts for the many-body character of the…

Soft Condensed Matter · Physics 2011-10-21 Noam Weil , Oded Farago

Quenched or frozen-in structural disorder is ubiquitous in real experimental systems. Much of the progress is achieved in understanding the phase separation of such systems using the diffusion-driven coarsening in Ising model with quenched…

Soft Condensed Matter · Physics 2023-08-15 Rounak Bhattacharyya , Bhaskar Sen Gupta

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

Biological Physics · Physics 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

We consider an "impurity" with a spin degree of freedom coupled to a finite reservoir of non-interacting electrons, a system which may be realized by either a true impurity in a metallic nano-particle or a small quantum dot coupled to a…

Mesoscale and Nanoscale Physics · Physics 2009-08-06 R. K. Kaul , D. Ullmo , G. Zarand , S. Chandrasekharan , H. U. Baranger

Collective behavior of proteins on biomembranes is usually studied within the spontaneous curvature model. Here we consider an alternative phenomenological approach, which accounts consistently for partial ordering of proteins as well as…

Soft Condensed Matter · Physics 2014-09-03 O. V. Manyuhina

Curvature-inducing proteins containing a Bin/Amphiphysin/Rvs domain often have intrinsically disordered domains. Recent experiments have shown that these disordered chains enhance curvature sensing and generation. Here, we report on the…

Soft Condensed Matter · Physics 2022-07-20 Hiroshi Noguchi

The adhesion dynamics of a membrane confined between two permeable walls is studied using a two-dimensional hydrodynamic model. The membrane morphology decomposes into adhesion patches on the upper and the lower walls and obeys a nonlinear…

Soft Condensed Matter · Physics 2014-09-16 Thomas Le Goff , Paolo Politi , Olivier Pierre-Louis
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