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We consider directed semiflexible polymers embedded in a fluctuating surface which is governed by either surface tension or bending rigidity. The attractive interactions induced by the fluctuations of the surface reduce the rigidity of the…

Condensed Matter · Physics 2009-10-28 Ramin Golestanian

We present Monte Carlo simulations of an ultra coarse-grained lipid bilayer with different number of lipids on both leaflets. In the simulations, we employ a new method for measuring the elastic parameters of the membrane, including the…

Soft Condensed Matter · Physics 2025-05-20 Oded Farago

We consider the role of nonlamellar-forming lipids in biological membranes by examining fluctuations, within the random phase approximation, of a model mixture of two lipids, one of which forms lamellar phases while the other forms inverted…

Soft Condensed Matter · Physics 2009-10-31 Xiao-jun Li , M. Schick

We analyze motility-induced phase separation and bubbly phase separation in a two-dimensional lattice model of self-propelled particles. We compare systems where the dense (liquid) phase has slab and droplet geometries. We find that…

Soft Condensed Matter · Physics 2025-03-18 Liheng Yao , Robert L. Jack

Current fluctuations in pure lipid membranes have been shown to occur under the influence of transmembrane electric fields (electroporation) as well as a result from structural rearrangements of the lipid bilayer during phase transition…

Biological Physics · Physics 2015-05-13 B. Wunderlich , C . Leirer , A-L. Idzko , U. F. Keyser , A. Wixforth , V. M. Myles , T. Heimburg , M. F. Schneider

We propose a model describing the phase behavior of two-component membranes consisting of binary mixtures of electrically charged and neutral lipids. We take into account the structural phase transition (main-transition) of the hydrocarbon…

Soft Condensed Matter · Physics 2016-07-11 Naofumi Shimokawa , Hiroki Himeno , Tsutomu Hamada , Masahiro Takagi , Shigeyuki Komura , David Andelman

We study the phase separation of binary lipid mixtures that form bicontinuous cubic phases. The competition between non-uniform Gaussian membrane curvature and line tension leads to a very rich phase diagram, where we observe symmetry…

Soft Condensed Matter · Physics 2016-08-24 Fabien Paillusson , Matthew R. Pennington , Halim Kusumaatmaja

From the perspective of physical properties, the cell membrane is an exotic two-dimensional material that has a dual nature: it exhibits characteristics of fluids, i.e., lipid molecules show lateral diffusion, while also demonstrating…

Soft Condensed Matter · Physics 2024-04-19 Vikash Pandey , Dhrubaditya Mitra

The supramolecular assembly of lipids into bilayer membranes is essential for cellular structure and function. However, the impact of lipid structural variations such as acyl chain length, degree of unsaturation, and headgroup type on…

Soft Condensed Matter · Physics 2024-12-13 Sonam Phuntsho

This article summarizes a variety of physical mechanisms proposed in the literature, which can generate micro- and nanodomains in multicomponent lipid bilayers and biomembranes. It mainly focusses on lipid-driven mechanisms that do not…

Biological Physics · Physics 2016-11-16 Friederike Schmid

Motivated by recent experimental work on multicomponent lipid membranes supported by colloidal scaffolds, we report an exhaustive theoretical investigation of the equilibrium configurations of binary mixtures on curved substrates. Starting…

Soft Condensed Matter · Physics 2018-09-12 Piermarco Fonda , Melissa Rinaldin , Daniela J. Kraft , Luca Giomi

The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or…

Soft Condensed Matter · Physics 2009-11-10 Pierre Sens

The effect of asymmetry in the transbilayer lipid distribution on the dynamics of phase separation in fluid vesicles is investigated numerically for the first time. This asymmetry is shown to set a spontaneous curvature for the domains that…

Soft Condensed Matter · Physics 2009-11-11 Mohamed Laradji , P. B. Sunil Kumar

We have explored the electronic properties of stacked graphene flakes with the help of the quantum chemistry methods. We found that the behavior of a bilayer system is governed by the strength of the repulsive interactions that arise…

Mesoscale and Nanoscale Physics · Physics 2015-05-27 Julia Berashevich , Tapash Chakraborty

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

We study the shape dynamics of a two-component fluid membrane, using a dynamical triangulation monte carlo simulation and a Langevin description. Phase separation induces morphology changes depending on the lateral mobility of the lipids.…

Soft Condensed Matter · Physics 2009-10-30 P. B. Sunil Kumar , Madan Rao

Fluid membranes made out of lipid bilayers are the fundamental separation structure in eukaryotic cells. Many physiological processes rely on dramatic shape and topological changes (e.g. fusion, fission) of fluid membrane systems. Fluidity…

Numerical Analysis · Mathematics 2010-07-29 Marino Arroyo , Antonio DeSimone , Luca Heltai

Many protein-protein interaction (PPI) networks take place in the fluid yet structured plasma membrane. Lipid domains, sometimes termed rafts, have been implicated in the functioning of various membrane-bound signaling processes. Here, we…

Biological Physics · Physics 2025-11-03 Taylor Schaffner , Benjamin B. Machta

The spatio-temporal organization of proteins and the associated morphological changes in membranes are of importance in cell signaling. Several mechanisms that promote the aggregation of proteins at low cell surface concentrations have been…

Biological Physics · Physics 2018-04-18 K. K. Sreeja , P. B. Sunil Kumar

It was recently discovered that friction between surfaces bearing phosphatidylcholine (PC) lipid bilayers can be increased by two orders of magnitude or more via an externally-applied electric field, and that this increase is fully…

Soft Condensed Matter · Physics 2024-09-26 Di Jin , Jacob Klein