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Recent single molecule experiments probing the passage process of a short single-stranded DNA (ssDNA) through a membrane channel (translocation) allow to measure the passage time distribution. Building on a recent modelling approach (D. K.…

Statistical Mechanics · Physics 2009-11-10 Ralf Metzler , Joseph Klafter

We demonstrate simultaneous measurements of DNA translocation into glass nanopores using ionic current detection and fluorescent imaging. We verify the correspondence between the passage of a single DNA molecule through the nanopore and the…

We explore the prospects to control by use of time-dependent fields quantum transport phenomena in nanoscale systems. In particular, we study for driven conductors the electron current and its noise properties. We review recent…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Sigmund Kohler , Jörg Lehmann , Peter Hänggi

The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA…

Organization and maintenance of the chromosomal DNA in living cells strongly depends on the DNA interactions with a plethora of DNA-binding proteins. Single-molecule studies show that formation of nucleoprotein complexes on DNA by such…

Biomolecules · Quantitative Biology 2018-09-05 Artem K. Efremov , Jie Yan

Laser-driven electron transport across a sample has garnered enormous attentions over several decades, as it provides a much faster way to control electron dynamics. Light is an electromagnetic wave, so how and why an electron can acquire a…

Materials Science · Physics 2024-12-09 Robert Meadows , Y. Xue , Nicholas Allbritton , G. P. Zhang

Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a…

Genomics · Quantitative Biology 2020-09-28 Giampaolo Cristadoro , Mirko Degli Esposti , Eduardo G. Altmann

We examine the impact of a complex absorbing potential on electron transport, both in the continuum and on a lattice. This requires the use of non-Hermitian Hamiltonians; the required formalism is briefly outlined. The lattice formulation…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Fatih Dogan , Wonkee Kim , C. M. Blois , F. Marsiglio

Quantun spin transport through a short DNA chain connected to ferromagnetic electrodes has been investigated by the transfer matrix method. We describe the system by a tight-binding model where the parameters are extracted from the…

Soft Condensed Matter · Physics 2009-11-11 X. F. Wang , Tapash Chakraborty

We review recent advances in the DNA sequencing based on the measurement of transverse electrical currents. Device configurations proposed in the literature are classified according to whether the molecular fingerprints appear as the major…

Mesoscale and Nanoscale Physics · Physics 2015-03-10 Han Seul Kim , Yong-Hoon Kim

Replication and transcription are two important processes in living systems. To execute such processes, various proteins work far away from equilibrium in a staggered way. Motivated by this, aspects of hysteresis during unzipping of DNA…

Soft Condensed Matter · Physics 2013-03-14 Garima Mishra , Poulomi Sadhukhan , Somendra M Bhattacharjee , Sanjay Kumar

Quantum transport properties of electron systems driven by strong electric fields are studied by mapping the Landau-Zener transition dynamics to a quantum walk on a semi-infinite one-dimensional lattice with a reflecting boundary, where the…

Quantum Physics · Physics 2016-09-08 Takashi Oka , Norio Konno , Ryotaro Arita , Hideo Aoki

DNA looping plays a fundamental role in a wide variety of biological processes, providing the backbone for long range interactions on DNA. Here we develop the first model for DNA looping by an arbitrarily large number of proteins and solve…

Subcellular Processes · Quantitative Biology 2007-05-23 Jose M. G. Vilar , Leonor Saiz

DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA…

Biomolecules · Quantitative Biology 2015-11-10 Stephanie Johnson , Martin Lindén , Rob Phillips

A tight-binding model together with a novel statistical method are used to investigate the relation between the sequence-dependent electric transport properties and the sequences of protein-coding regions of complete genomes. A correlation…

Biological Physics · Physics 2009-11-11 C. T. Shih

The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the…

Soft Condensed Matter · Physics 2007-05-23 S. Tuukkanen , A. Kuzyk , J. J. Toppari , V. P. Hytonen , T. Ihalainen , P. Torma

In recent years, significant progress in understanding the properties of supercoiled DNA has been obtained due to nanotechniques that made stretching and twisting of single molecules possible. Quantitative interpretation of such experiments…

Biomolecules · Quantitative Biology 2015-06-05 Alexey K. Mazur

We have examined the electrical transport in disordered molecular solids. It has been found that mobility is a function of electric field and temperature due to hopping conduction. Several theoretical models for charge transport in…

Materials Science · Physics 2007-05-23 Ajit Kumar Mahapatro , Subhasis Ghosh

A model is proposed to interpret the experimental I-V curves Polyguanine-Polycytosine DNA molecules.

Materials Science · Physics 2007-05-23 J H Wei , K S Chan

Recently, some authors have shown that a DNA molecule produces electromagnetic signals and communicates with other DNA molecules or other molecules. In fact, a DNA acts like a receiver or transmitter of radio waves. In this paper, we…

Biological Physics · Physics 2018-08-03 Alireza Sepehri