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Single molecule studies, at constant force, of the separation of double-stranded DNA into two separated single strands may provide information relevant to the dynamics of DNA replication. At constant applied force, theory predicts that the…

We study phenomenological scaling theories of the polymer dynamics in random media, employing the existing scaling theories of polymer chains and the percolation statistics. We investigate both the Rouse and the Zimm model for Brownian…

Soft Condensed Matter · Physics 2015-06-24 Bikas K. Chakrabarti , Amit K. Chattopadhyay , Amit Dutta

We present quantitative results for the drift velocity of a polymer in a gel if a force (e.g. through an electric or magnetic field) acts on a tag, attached to one of its ends. This is done by introducing a modification of the…

Condensed Matter · Physics 2009-10-28 G. T. Barkema , G. M. Schütz

The question of how stiff polymers are able to pack into small containers is particularly relevant to the study of DNA packaging in viruses. A reduced version of the problem based on coarse-grained representations of the main components of…

Biomolecules · Quantitative Biology 2016-10-12 D. C. Rapaport

We present a self-contained theory for the mechanical response of DNA in single molecule experiments. Our model is based on a 1D continuum description of the DNA molecule and accounts both for its elasticity and for DNA-DNA electrostatic…

Biomolecules · Quantitative Biology 2015-05-13 N. Clauvelin , B. Audoly , S. Neukirch

We propose a combined experimental (Atomic Force Microscopy) and theoretical study of the structural and dynamical properties of nucleosomes. In contrast to biochemical approaches, this method allows to determine simultaneously the DNA…

The response of a semiflexible polyelectrolyte chain to stretching in the regimes of moderate and weak screening is studied theoretically, with a special focus on DNA experiments. By using the nonlinear Poisson--Boltzmann description of…

Soft Condensed Matter · Physics 2007-05-23 Alexei V. Tkachenko

The sequence-dependent elasticity of double-helical DNA on a nm length scale can be captured by the rigid base-pair model, whose strains are the relative position and orientation of adjacent base-pairs. Corresponding elastic potentials have…

Biomolecules · Quantitative Biology 2013-05-29 Nils B. Becker , Ralf Everaers

The damping effect to the DNA bubble is investigated within the Peyrard-Bishop model. In the continuum limit, the dynamics of the bubble of DNA is described by the damped nonlinear Schrodinger equation and studied by means of variational…

Biomolecules · Quantitative Biology 2012-06-25 A. Sulaiman , F. P. Zen , H. Alatas , L. T. Handoko

We investigate the statistical mechanics of a torsionally constrained polymer. The polymer is modeled as a fluctuating rod with bend stiffness A kT and twist stiffness C kT. In such a model, thermal bend fluctuations couple geometrically to…

Soft Condensed Matter · Physics 2009-10-30 J. David Moroz , Philip Nelson

Loop formation between monomers in the interior of semiflexible chains describes elementary events in biomolecular folding and DNA bending. We calculate analytically the interior distance distribution function for semiflexible chains using…

Soft Condensed Matter · Physics 2009-11-11 Changbong Hyeon , D. Thirumalai

This work examines field theories for RNA-like polymers with single strand and double strand polymers and a periodic base sequence. These field theories originate from lattice models, describe polymers in a good solvent, and in principle…

Soft Condensed Matter · Physics 2024-06-10 R. Dengler

G-quadruplexes are non-canonical DNA structures rather ubiquitous in human genome, which are thought to play a crucial role in the development of 85-90 % of cancers. Here, we present a novel coarse-grained approach in modeling…

DNA polymerases are an essential class of enzymes or molecular motors that catalyze processive DNA syntheses during DNA replications. A critical issue for DNA polymerases is their molecular mechanism of processive DNA replication. We have…

Soft Condensed Matter · Physics 2021-11-01 Yu-Ru Liu , Peng-Ye Wang , Wei Li , Ping Xie

The dynamical scaling properties of selfavoiding polymerized membranes with internal dimension D are studied using model A dynamics. It is shown that the theory is renormalizable to all orders in perturbation theory and that the dynamical…

Condensed Matter · Physics 2009-10-30 Kay Joerg Wiese

Motivated by recent experiments probing shape, size and dynamics of bacterial chromosomes in growing cells, we consider a polymer model consisting of a circular backbone to which side-loops are attached, confined to a cylindrical cell. Such…

Biological Physics · Physics 2019-05-13 Pinaki Swain , Bela M. Mulder , Debasish Chaudhuri

We study bottlebrush macromolecules in a good solvent by small-angle neutron scattering (SANS), static light scattering (SLS), and dynamic light scattering (DLS). These polymers consist of a linear backbone to which long side chains are…

Soft Condensed Matter · Physics 2009-11-13 S. Bolisetty , C. Airaud , Y. Xu , A. H. E. Mueller , L. Harnau , S. Rosenfeldt , P. Lindner , M. Ballauff

A discrete nonlinear Schrodinger (NLS) model with long-range dispersive interactions describing the dynamical structure of DNA is proposed. Dispersive interactions of two types: the power dependence $r^{-s}$ and the exponential dependence…

The presence of slipknots in configurations of proteins and DNA has been shown to affect their functionality, or alter it entirely. Historically, polymers are modeled as polygonal chains in space. As an alternative to space curves, we…

Geometric Topology · Mathematics 2018-03-21 Harrison Chapman

DNA torsion dynamics is essential in the transcription process; simple models for it have been proposed by several authors, in particular Yakushevich (Y model). These are strongly related to models of DNA separation dynamics such as the one…

Biomolecules · Quantitative Biology 2009-11-13 Mariano Cadoni , Roberto De Leo , Sergio Demelio , Giuseppe Gaeta
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