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Active filaments, such as microtubules with attached cargo-carrying motor proteins, are important dynamic structures for fluid transport in and around living cells. The mathematical models of active filaments appearing in the literature…

Fluid Dynamics · Physics 2025-08-19 Ilteber R. Ozdemir , Bethany Clarke , Yongyun Hwang , Eric E. Keaveny

We study the dynamics and patterning of polar contractile filaments on the surface of a cylindrical cell using active hydrodynamic equations that incorporate couplings between curvature and filament orientation. Cables and rings…

Soft Condensed Matter · Physics 2015-06-05 Pragya Srivastava , Roie Shlomovitz , Nir S. Gov , Madan Rao

Recent experimental investigations into Hydra regeneration revealed a remarkable phenomenon: the morphological transformation of a tissue fragment from the incipient spherical configuration to a tube-like structure - the hallmark of a…

Biological Physics · Physics 2024-05-07 Oded Agam , Erez Braun

We experimentally and theoretically study the dynamics of a low-Reynolds number helical swimmer moving across viscosity gradients. Experimentally, a double-layer viscosity is generated by superposing two miscible fluids with similar…

Bacterial flagellar motor (BFM) is one of the ion-driven molecular machines, which drives the rotation of flagellar filaments and enable bacteria to swim in viscous solutions. Understanding its mechanism is one challenge in biophysics.…

Biological Physics · Physics 2015-03-06 Yunxin Zhang

The accumulation of swimming bacteria near surfaces may lead to biological processes such as biofilm formation and wound infection. Previous experimental observations of Vibrio alginolyticus showed an interesting correlation between the…

Biological Physics · Physics 2023-07-04 Vahid Nourian , Henry Shum

A small model polypeptide represented in atomic detail is folded using Monte Carlo dynamics. The polypeptide is designed to have a native conformation similar to the central part of the helix-turn-helix protein ROP. Starting from a…

Biological Physics · Physics 2008-02-03 D. Hoffmann , E. W. Knapp

The elastic properties of two-component bilayer membranes are studied using a coarse grain model for amphiphilic molecules. The two species of amphiphiles considered here differ only in their length. Molecular Dynamics simulations are…

Soft Condensed Matter · Physics 2007-05-23 Alberto Imparato , Julian C. Shillcock , Reinhard Lipowsky

In view of the important role helix-sheet transitions play in protein aggregation, we introduce a simple model to study secondary structural transitions of helix-coil-sheet systems using a Potts model starting with an effective Hamiltonian.…

Biological Physics · Physics 2011-11-09 John S. Schreck , Jian-Min Yuan

The conformations and dynamics of semiflexible filaments subject to a homogeneous external (gravitational) field, e.g., in a centrifuge, are studied numerically and analytically. The competition between hydrodynamic drag and bending…

Biological Physics · Physics 2016-08-23 G. Saggiorato , J. Elgeti , R. G. Winkler , G. Gompper

Systems with two species of active molecular motors moving on (cytoskeletal) filaments into opposite directions are studied theoretically using driven lattice gas models. The motors can unbind from and rebind to the filaments. Two motors…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we…

Fluid Dynamics · Physics 2018-02-14 Hanliang Guo , Lisa Fauci , Michael Shelley , Eva Kanso

We have employed molecular dynamics simulations based on the TIP4P/2005 water model to investigate the local structural, dynamical, and dielectric properties of the two recently reported body-centered-cubic and face-centered-cubic plastic…

Soft Condensed Matter · Physics 2019-04-03 Ioannis Skarmoutsos , Stefano Mossa , Elvira Guardia

We analyze experimentally the shape of a long elastic filament rotating in a viscous liquid. We identify a continuous but sharp transition from a straight to an helical shape, resulting from the competition between viscous stresses and…

Fluid Dynamics · Physics 2009-11-13 Naïs Coq , Olivia Du Roure , Joel Marthelot , Denis Bartolo , Marc Fermigier

In the presence of a finite interlayer displacement field bilayer graphene has an energy gap that is dependent on stacking and largest for the stable AB and BA stacking arrangements. When the relative orientations between layers are twisted…

Mesoscale and Nanoscale Physics · Physics 2018-07-11 Dmitry K. Efimkin , Allan H. MacDonald

Bacterial swimming is well characterized in uniform liquids at rest. The natural habitat of bacterial swimmers, however, is often dominated by moving fluids and interfaces, resulting in shear flows that may strongly alter bacterial…

Horizontal gene transfer is an important factor in bacterial evolution that can act across species boundaries. Yet, we know little about rate and genomic targets of cross-lineage gene transfer, and about its effects on the recipient…

Populations and Evolution · Quantitative Biology 2022-10-12 Jeffrey J. Power , Fernanda Pinheiro , Simone Pompei , Viera Kovacova , Melih Yüksel , Isabel Rathmann , Mona Förster , Michael Lässig , Berenike Maier

We theoretically investigate the dynamics of a floating lipid bilayer membrane coupled with a two-dimensional cytoskeleton network, taking into explicitly account the intermonolayer friction, the discrete lattice structure of the…

Soft Condensed Matter · Physics 2017-08-02 Ryuichi Okamoto , Shigeyuki Komura , Jean-Baptiste Fournier

We investigate an analytically tractable toy model for thermally induced polymorphic dynamics of cooperatively rearranging biofilaments - like microtubules. The proposed 4 -block model, which can be seen as a coarse-grained approximation of…

Soft Condensed Matter · Physics 2016-08-14 Hervé Mohrbach , Igor M. Kulić

Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various crosslinking and other associated proteins largely determine the (visco)elastic response of cells. In this letter we…

Disordered Systems and Neural Networks · Physics 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh