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The past decade has witnessed the development and success of coarse-grained network models of proteins for predicting many equilibrium properties related to collective modes of motion. Curiously, the results are usually robust towards the…

Biomolecules · Quantitative Biology 2010-02-04 Canan Atilgan , Osman Burak Okan , Ali Rana Atilgan

In this paper we present the results of numerical simulations intended to study the behavior of non-Abelian cosmic strings networks. In particular we are interested in discussing the variations in the asymptotic behavior of the system as we…

Cosmology and Nongalactic Astrophysics · Physics 2016-06-17 G. Cella , M. Pieroni

We study the dynamical properties of the ordered phases obtained in a coupled nonequilibrium system describing advection of two species of particles by a stochastically evolving landscape. The local dynamics of the landscape also gets…

Statistical Mechanics · Physics 2017-08-23 Shauri Chakraborty , Sakuntala Chatterjee , Mustansir Barma

The proper biological functioning of proteins often relies on the occurrence of coordinated fluctuations around their native structure, or of wider and sometimes highly elaborated motions. Coarse-grained elastic-network descriptions are…

Biomolecules · Quantitative Biology 2013-10-17 Yves Dehouck , Alexander S. Mikhailov

To analyze the evolutionary emergence of structural complexity in physical processes we introduce a general, but tractable, model of objects that interact to produce new objects. Since the objects--\emph{$epsilon$-machines}--have well…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 James P. Crutchfield , Olof Gornerup

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

Genetic information and environmental factors determine the path of an individuals life and therefore, the evolution of its entire species. We have succeeded in proposing and studying a model that captures this idea. In our model, a…

Populations and Evolution · Quantitative Biology 2021-07-28 N. Abadi , G. Abramson

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

We use numerical simulations to show how a fully flexible filament binding to a deformable cylindrical surface may acquire a macroscopic persistence length and a helical conformation. This is a result of the nontrivial elastic response to…

Soft Condensed Matter · Physics 2015-03-17 Andela Šarić , Josep C. Pàmies , Angelo Cacciuto

A coarse grained model of a random polypeptide chain, with only discrete torsional degrees of freedom and Hookean springs connecting pairs of hydrophobic residues is shown to display stretched exponential relaxation under Metropolis…

Soft Condensed Matter · Physics 2009-10-31 Erkan Tuzel , Ayse Erzan

We describe a numerical simulation of the evolution of an $S_3$ cosmic string network which takes fully into account the non-commutative nature of the cosmic string fluxes and the topological obstructions which hinder strings from moving…

Astrophysics · Physics 2009-10-30 Patrick N. McGraw

Inspired by experiments on dynamic extensile gels of biofilaments and motors, we propose a model of a network of linear springs with a kinetics consisting of growth at a prescribed rate, death after a lifetime drawn from a distribution, and…

Soft Condensed Matter · Physics 2019-01-25 Daniel Goldstein , Sriram Ramaswamy , Bulbul Chakraborty

In this work, we discovered a fundamental connection between selection for protein stability and emergence of preferred structures of proteins. Using standard exact 3-dimensional lattice model we evolve sequences starting from random ones…

Genomics · Quantitative Biology 2007-05-23 Konstantin B. Zeldovich , Igor N. Berezovsky , Eugene I. Sha

Helical objects are often implemented in electronic or mechanical micro-systems, requiring a precise understanding of their mechanical properties. While helices formed by cylindrical filaments have been intensely investigated, little is…

Applied Physics · Physics 2022-08-22 Lucas Prévost , Anke Lindner , Olivia du Roure

The low-energy physics of (quasi)degenerate one-dimensional systems is typically understood as the particle-like dynamics of kinks between stable, ordered structures. Such dynamics, we show, becomes highly non-trivial when the ground states…

Soft Condensed Matter · Physics 2014-11-27 Cristiano Nisoli , Alexander V. Balatsky

A framework is presented for understanding the common character of proteins. Proteins are linear chain molecules. However, the simple model of a polymer viewed as spheres tethered together does not account for many of the observed…

Statistical Mechanics · Physics 2009-11-10 Jayanth R. Banavar , Amos Maritan

We extend and develop our previous work on the evolution of a network of cosmic strings. The new treatment is based on an analysis of the probability distribution of the end-to-end distance of a randomly chosen segment of left-moving string…

High Energy Physics - Phenomenology · Physics 2016-09-01 Daren Austin , E. J. Copeland , T. W. B. Kibble

The adoption of agroecological practices will be crucial to address the challenges of climate change and biodiversity loss. Such practices favor the cultivation of plants in complex mixtures with layouts differing from the monoculture…

Populations and Evolution · Quantitative Biology 2024-09-26 Julian Talbot , Pascal Viot , David Colliaux

Species complexes are groups of closely related populations exchanging genes through dispersal. We study the dynamics of the structure of species complexes in a class of metapopulation models where demes can exchange genetic material…

Populations and Evolution · Quantitative Biology 2026-03-26 Amaury Lambert , Emmanuel Schertzer , Yannic Wenzel

Biological molecules can form hydrogen bonds between nearby residues, leading to helical secondary structures. The associated reduction of configurational entropy leads to a temperature dependence of this effect: the "helix-coil…

Soft Condensed Matter · Physics 2009-11-07 S. Kutter , E. M. Terentjev