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Cells attach to their environment by means of focal adhesions, which are molecular complexes that exhibit the remarkable ability to adapt to mechanical load by changing their size. Drawing from the biomolecular mechanisms underlying this…

Soft Condensed Matter · Physics 2025-03-17 Anton F. Burnet , Julia Müllner , Benedikt Sabass

Nonlinear dynamics of photoinduced cooperative phenomena is studied by numerical calculations on a model of molecular crystals. We found that the photoinduced nucleation process is triggered only when certain amount of excitation energy is…

Computational Physics · Physics 2009-11-13 Kunio Ishida , Keiichiro Nasu

Morphogenetic dynamics of tissue sheets require coordinated cell shape changes regulated by global patterning of mechanical forces. Inspired by such biological phenomena, we propose a minimal mechanochemical model based on the notion that…

Soft Condensed Matter · Physics 2021-01-01 Andrei Zakharov , Kinjal Dasbiswas

Conformational transitions in macromolecular complexes often involve the reorientation of lever-like structures. Using a simple theoretical model, we show that the rate of such transitions is drastically enhanced if the lever is bendable,…

Biomolecules · Quantitative Biology 2009-11-13 Richard A. Neher , Wolfram Mobius , Erwin Frey , Ulrich Gerland

We investigate the influence of thermally activated internal molecular dynamics on the phase shifts of matter waves inside a molecule interferometer. While de Broglie physics generally describes only the center-of-mass motion of a quantum…

If time-dependent disruptions from slow-roll occur during inflation, the correlation functions of the primordial curvature perturbation should have scale-dependent features, a case which is marginally supported from the cosmic microwave…

Cosmology and Nongalactic Astrophysics · Physics 2018-06-04 Jinn-Ouk Gong , Gonzalo A. Palma , Spyros Sypsas

In this paper, we discuss microscopic models for chiral active particles, i.e., rotating active units that exhibit circular or spinning motion. While non-chiral active particles are typically governed by self-propulsion and conservative…

Soft Condensed Matter · Physics 2025-10-20 Lorenzo Caprini , Alessandro Petrini , Umberto Marini Bettolo Marconi

Evolution in time-varying environments naturally leads to adaptable biological systems that can easily switch functionalities. Advances in the synthesis of environmentally-responsive materials therefore open up the possibility of creating a…

Biological membranes are shaped by various proteins that either generate inward or outward membrane curvature. In this article, we investigate the membrane morphologies induced by mixtures of arc-shaped particles with coarse-grained…

Subcellular Processes · Quantitative Biology 2020-04-03 Francesco Bonazzi , Carol K. Hall , Thomas R. Weikl

Models based on surfactant driven instabilities have been employed to describe pattern formation by swarming bacteria. However, by definition, such models cannot account for the effect of bacterial sensing and decision making. Here we…

We formulate a theory of electrostatic interactions in lipid bilayer membranes where both monolayer leaflets contain dissociable moieties that are subject to charge regulation. We specifically investigate the coupling between membrane…

Soft Condensed Matter · Physics 2022-04-01 Petch Khunpetch , Arghya Majee , Rudolf Podgornik

We study an agent-based model of self-propelled particles with a velocity-dependent alignment rule. This interaction is orientation weighted and acts along the line connecting neighboring particles. Tuning the alignment strength produces…

Soft Condensed Matter · Physics 2026-05-19 Bohdan Dobosh , Alexander Yakimenko

Block copolymer melts self-assemble in the bulk into a variety of nanostructures, making them perfect candidates to template the position of nanoparticles. The morphological changes of block copolymers are studied in the presence of a…

Soft Condensed Matter · Physics 2019-10-31 Javier Diaz , Marco Pinna , Andrei V. Zvelindovsky , Ignacio Pagonabarraga

The physics of micron-scale biological colonies usually benefits from different out-of-equilibrium sources. In bacterial colonies and cellular tissues, the growth process is among the important active sources that determine the dynamics. In…

Soft Condensed Matter · Physics 2023-06-16 Forouh Maleki , Ali Najafi

Many types of mammalian cells exert active contractile forces and mechanically deform their elastic substrate, to accomplish biological functions such as cell migration. These substrate deformations provide a mechanism by which cells can…

Soft Condensed Matter · Physics 2022-02-22 Subhaya Bose , Patrick S. Noerr , Ajay Gopinathan , Arvind Gopinath , Kinjal Dasbiswas

Bacterial microcompartments are large, roughly icosahedral shells that assemble around enzymes and reactants involved in certain metabolic pathways in bacteria. Motivated by microcompartment assembly, we use coarse-grained computational and…

Biological Physics · Physics 2019-05-07 Farzaneh Mohajerani , Michael F. Hagan

We present a generic framework for modelling three-dimensional deformable shells of active matter that captures the orientational dynamics of the active particles and hydrodynamic interactions on the shell and with the surrounding…

Soft Condensed Matter · Physics 2019-11-20 Luuk Metselaar , Julia M. Yeomans , Amin Doostmohammadi

Polymers adopt extended coil and compact globule states according to the balance between entropy and interaction energies. The transition of a polymer between an extended coil state and compact globule state can be induced by changing…

Soft Condensed Matter · Physics 2015-10-28 Kenta Odagiri , Kazuhiko Seki

Circuit topology refers to the arrangement of interactions between objects belonging to a linearly ordered object set. Linearly ordered set of objects are common in nature and occur in a wide range of applications in economics, computer…

Disordered Systems and Neural Networks · Physics 2015-09-02 Alireza Mashaghi , Abolfazl Ramezanpour

Biological nanomachines are nanometer-size macromolecular complexes that catalyze chemical reactions in the presence of substrate molecules. The catalytic functions carried out by such nanomachines in the cytoplasm, and biological membranes…

Soft Condensed Matter · Physics 2022-11-22 Yuto Hosaka , Shigeyuki Komura