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Investigations of natural variation in cell mechanics within a cell population are essential to understand the stochastic nature of soft-network deformation. Striking commonalities have been found concerning the average values and…

Cell Behavior · Quantitative Biology 2011-06-22 John M. Maloney , Krystyn J. Van Vliet

We consider the phase transition of a string with tension $\eps_1$ to a string with a smaller tension $\eps_2$. The transition proceeds through quantum tunneling, and we calculate in arbitrary number of dimensions the pre-exponential factor…

High Energy Physics - Theory · Physics 2008-11-26 A. Monin , M. B. Voloshin

Two dimensional simulations of non-cohesive granular matter in a biaxial shear tester are discussed. The effect of particle elasticity on the mechanical behavior is investigated using two complementary distinct element methods (DEM): Soft…

Computational Physics · Physics 2011-03-11 Dirk Kadau , Dominik Schwesig , Joerg Theuerkauf , Dietrich E. Wolf

We present theoretical and numerical studies on stiff, linear polyelectrolytes within the framework of the cell model. We first review analytical results obtained on a mean-field Poisson-Boltzmann level, and then use molecular dynamics…

Soft Condensed Matter · Physics 2009-11-07 Markus Deserno , Christian Holm

We focused on elastic properties of B- and N-doped graphene in wide range of concentrations up to 20%. The Young's, bulk and shear moduli and Poisson's ratio have been calculated by means of the density functional theory for a…

Materials Science · Physics 2013-10-08 Karolina Z. Milowska , Magdalena Woinska , Malgorzata Wierzbowska

Mechanical forces influence the dynamics of growing tissues. Computer simulations are employed to study the importance of interfacial effects in tissue competition. It was speculated that mechanical pressure determines the competition,…

Biological Physics · Physics 2024-06-03 Nirmalendu Ganai , Tobias Buscher , Gerhard Gompper , Jens Elgeti

Shear thickening of particle suspensions is characterized by a transition between lubricated and frictional contacts between the particles. Using 3D numerical simulations, we study how the inter-particle friction coefficient influences the…

Soft Condensed Matter · Physics 2020-01-08 Vishnu Sivadasan , Eric Lorenz , Alfons G. Hoekstra , Daniel Bonn

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

Biological Physics · Physics 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and numerous experiments confirm the viscoelastic properties of…

Tissues and Organs · Quantitative Biology 2017-10-20 M. D. Peters , D. Iber

Auxetic materials are a novel class of mechanical metamaterials which exhibit an interesting property of negative Poisson ratio by virtue of their architecture rather than composition. It has been well established that a wide range of…

Applied Physics · Physics 2017-08-02 Krishna Kumar Saxena , Raj Das , Emilio P Calius

Cell growth, division and death are defining features of biological tissues that contribute to morphogenesis. In hydrodynamic descriptions of cohesive tissues, their occurrence implies a non-zero rate of variation of cell density. We show…

Tissues and Organs · Quantitative Biology 2017-08-23 Shunsuke Yabunaka , Philippe Marcq

Large-scale blockages like buildings affect the performance of urban cellular networks, especially at higher frequencies. Unfortunately, such blockage effects are either neglected or characterized by oversimplified models in the analysis of…

Information Theory · Computer Science 2013-09-18 Tianyang Bai , Rahul Vaze , Robert W. Heath

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

We study a generic model for the polarisation and motility of self-propelled soft objects, biological cells or biomimetic systems, interacting with a viscous substrate. The active forces generated by the cell on the substrate are modelled…

Soft Condensed Matter · Physics 2015-06-23 M. Leoni , P. Sens

The behaviour of elastic structures undergoing large deformations is the result of the competition between confining conditions, self-avoidance and elasticity. This combination of multiple phenomena creates a geometrical frustration that…

Soft Condensed Matter · Physics 2015-05-19 Mokhtar Adda-Bedia , Arezki Boudaoud , Laurent Boué , Stephanie Deboeuf

We investigate random graphs on the points of a Poisson process in $d$-dimensional space, which combine scale-free degree distributions and long-range effects. Every Poisson point carries an independent random mark and given marks and…

Probability · Mathematics 2022-05-02 Peter Gracar , Markus Heydenreich , Christian Mönch , Peter Mörters

In recent years, new flexible functional materials have attracted increasing interest, but there is a lack of the designing mechanisms of flexibility design with superstructures. In traditional engineering mechanics, the maximum bending…

Soft Condensed Matter · Physics 2023-09-06 Yang Li , Le Zhang , Dehua Wang , Limei Hou , Shanmei Du , Yang Deng , Yanfeng Du , Yingfei Xin , Chongyang Fu , Yan Gu , Xiaoxiong Wang

We investigate the question of stability of a solid thin film which experiences external interactions such as van der Waals forces from a contacting surface or forces from an external electric field. Both perfectly elastic and viscoelastic…

Materials Science · Physics 2007-05-23 Vijay Shenoy , Ashutosh Sharma

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

Implant placement under soft tissues operation is described. In this operation tissues can reach such deformations that nonlinear properties are appeared. A mass-spring model modification for modeling nonlinear tissue operation is…

Numerical Analysis · Computer Science 2014-03-11 Sergei Nikolaev