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The miscible displacement of a shear-thinning fluid by another of same rheological properties is studied experimentally in a transparent fracture by an optical technique imaging relative concentration distributions. The fracture walls have…

Membrane proteins are crucial in regulating biomembrane shapes and controlling the dynamic changes in membrane morphology during essential cellular processes. These proteins can localize to regions with their preferred curvatures (curvature…

Soft Condensed Matter · Physics 2025-05-26 Hiroshi Noguchi

Random lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when this lateral random diffusion is mediated by the electrostatic…

Quantitative Methods · Quantitative Biology 2015-06-03 Y. C. Zhou

Diffusion in an evolving environment is studied by continuos-time Monte Carlo simulations. Diffusion is modelled by continuos-time random walkers on a lattice, in a dynamic environment provided by bubbles between two one-dimensional…

Soft Condensed Matter · Physics 2010-11-22 Janne Juntunen , Juha Merikoski

Active contributions to fluctuations are a direct consequence of metabolic energy consumption in living cells. Such metabolic processes continuously create active forces, which deform the membrane to control motility, proliferation as well…

Biological Physics · Physics 2018-10-02 Hervé Turlier , Timo Betz

To explain the appearance of heterogeneities in the plasma membrane, I propose a hypothesis which begins with the observation that fluctuations in the membrane curvature are coupled to the difference between compositions in one leaf and the…

Soft Condensed Matter · Physics 2017-08-23 M. Schick

The fluctuation pressure of a lipid-bilayer membrane is important for the stability of lamellar phases and the adhesion of membranes to surfaces. In contrast to many theoretical studies, which predict a decrease of the pressure with the…

Soft Condensed Matter · Physics 2013-07-25 Thorsten Auth , Gerhard Gompper

Temporally and spatially resolved measurements of protein transport inside cells provide important clues to the functional architecture and dynamics of biological systems. Fluorescence Recovery After Photobleaching (FRAP) technique has been…

Subcellular Processes · Quantitative Biology 2009-03-04 George D. Tsibidis

We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of…

Probability · Mathematics 2020-03-18 Mark Freidlin , Leonid Koralov

Tracer diffusion and hydrodynamic dispersion in two-dimensional fractures with self-affine roughness is studied by analytic and numerical methods. Numerical simulations were performed via the lattice-Boltzmann approach, using a new boundary…

Statistical Mechanics · Physics 2016-08-31 German Drazer , Joel Koplik

We investigate membrane-mediated interactions between transmembrane proteins using coarse-grained models. We compare the effective potential of mean force (PMF) between two proteins, which are always aligned parallel to the z-axis of the…

Biological Physics · Physics 2012-04-11 Joerg Neder , Beate West , Peter Nielaba , Friederike Schmid

A formal analogy of fluctuating diffusivity to thermodynamics is discussed for messenger RNA molecules fluorescently fused to a protein in living cells. Regarding the average value of the fluctuating diffusivity of such RNA-protein…

Statistical Mechanics · Physics 2021-03-17 Yuichi Itto

A tethered vesicle, which consists of a cylindrical membrane tube and a spherical vesicle, is produced by a mechanical force that is experimentally imposed by optical tweezers and a micropipette. This tethered vesicle is employed for…

Soft Condensed Matter · Physics 2021-12-30 Hiroshi Noguchi

The physical approach of a small particle (virus, medical drug) to the cell membrane represents the crucial first step before active internalization and is governed by thermal diffusion. Using a fully analytical theory we show that the…

Fluid Dynamics · Physics 2016-02-17 Abdallah Daddi-Moussa-Ider , Achim Guckenberger , Stephan Gekle

The quantitative understanding of membranes is still rooted in work performed in the 1970s by Helfrich and others, concerning amphiphilic bilayers. However, most biological membranes contain a wide variety of nonamphiphilic molecules too.…

Soft Condensed Matter · Physics 2014-06-10 Richard G. Morris

Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

Fluid Dynamics · Physics 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

We calculate the fluctuation spectrum of the shape of a lipid vesicle or cell exposed to a nonthermal source of noise. In particular we take into account constraints on the membrane area and the volume of fluid that it encapsulates when…

Soft Condensed Matter · Physics 2013-11-07 Bastien Loubet , Udo Seifert , Michael Andersen Lomholt

The phase diagram of an incompressible fluid membrane subject to quantum and thermal fluctuations is calculated exactly in a large number of dimensions of configuration space. At zero temperature, a crumpling transition is found at a…

Condensed Matter · Physics 2009-10-31 M. E. S. Borelli , H. Kleinert

Lipid membranes constitute very particular materials: on the one hand, they break very easily under microscopical stretching; on the other hand, they are extremely flexible, presenting deformations even at small scales. Consequently, a…

Soft Condensed Matter · Physics 2010-11-09 Camilla Barbetta

Protein dynamics is a fundamental element to comprehend their biological functions. However, a theoretical picture providing microscopic-detail explanation of its relevant features is still missing. One of the outmost relevant properties…

Soft Condensed Matter · Physics 2023-06-14 Luca Maggi