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The biological cell exhibits a fantastic range of behaviors, but ultimately these are governed by a handful of physical and chemical principles. Here we explore simple theory, known for decades and based on the simple thermodynamics of…

Biomolecules · Quantitative Biology 2020-03-25 Daniel M. Zuckerman

Path thermodynamic formulation of non-equilibrium reactive systems is considered. It is shown through simple practical examples that this approach can lead to results that contradict well established thermodynamic properties of such…

Mathematical Physics · Physics 2020-05-27 M. Malek Mansour , Alejandro L. Garcia

We consider the Gibbs representation over space-time of non-equilibrium dynamics of Hamiltonian systems defined on a lattice with local interactions. We first write the corresponding action functional as a sum of local terms, defining a…

Mathematical Physics · Physics 2009-11-11 Raphael Lefevere

Biological assemblies such as chromosomes, membranes, and the cytoskeleton are driven out of equilibrium at the nanoscale by enzymatic activity and molecular motors. Similar non-equilibrium dynamics can be realized in synthetic systems,…

Biological Physics · Physics 2020-06-04 Federica Mura , Grzegorz Gradziuk , Chase P. Broedersz

We present a combined theoretical approach to study the nonequilibrium transport properties of nanoscale systems coupled to metallic electrodes and exhibiting strong electron-phonon interactions. We use the Keldysh Green function formalism…

Mesoscale and Nanoscale Physics · Physics 2015-05-20 R. C. Monreal , F. Flores , A. Martin-Rodero

Nonequilibrium collective motion is ubiquitous in nature and often results in a rich collection of intringuing phenomena, such as the formation of shocks or patterns, subdiffusive kinetics, traffic jams, and nonequilibrium phase…

Statistical Mechanics · Physics 2011-12-20 Mauro Mobilia , Tobias Reichenbach , Hauke Hinsch , Thomas Franosch , Erwin Frey

The objective of this paper is to describe a simple phenomenological approach for including incoherent dephasing processes in quantum transport models. The presented illustrative numerical results show this model provides the flexibility of…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Roksana Golizadeh-Mojarad , Supriyo Datta

We show that transport in the presence of entropic barriers exhibits peculiar characteristics which makes it distinctly different from that occurring through energy barriers. The constrained dynamics yields a scaling regime for the particle…

Statistical Mechanics · Physics 2009-11-11 D. Reguera , G. Schmid , P. S. Burada , J. M. Rubí , P. Hänggi

This paper reviews some selected approaches to the description of transport properties, mainly electroconductivity, in crystalline and disordered metallic systems. A detailed qualitative theoretical formulation of the electron transport…

Statistical Mechanics · Physics 2011-09-27 A. L. Kuzemsky

All living cells transport molecules and ions across membranes, often against concentration gradients. This active transport requires continual energy expenditure and is clearly a nonequilibrium process for which standard equilibrium…

Subcellular Processes · Quantitative Biology 2007-05-23 Robert W. Finkel

Stochastic systems often exhibit multiple viable metastable states that are long-lived. Over very long timescales, fluctuations may push the system to transition between them, drastically changing its macroscopic configuration. In realistic…

Statistical Mechanics · Physics 2023-04-14 Tobias Grafke , Alessandro Laio

We study long-range interacting systems driven by external stochastic forces that act collectively on all the particles constituting the system. Such a scenario is frequently encountered in the context of plasmas, self-gravitating systems,…

Statistical Mechanics · Physics 2013-12-03 Cesare Nardini , Shamik Gupta , Stefano Ruffo , Thierry Dauxois , Freddy Bouchet

We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

Statistical Mechanics · Physics 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

We develop a general kinetic theory framework to describe the hydrodynamics of strongly interacting, nonequilibrium quantum systems in which integrability is weakly broken, leaving a few residual conserved quantities. This framework is…

Statistical Mechanics · Physics 2021-03-03 Javier Lopez-Piqueres , Brayden Ware , Sarang Gopalakrishnan , Romain Vasseur

Biological nanomachines are nanometer-size macromolecular complexes that catalyze chemical reactions in the presence of substrate molecules. The catalytic functions carried out by such nanomachines in the cytoplasm, and biological membranes…

Soft Condensed Matter · Physics 2022-11-22 Yuto Hosaka , Shigeyuki Komura

We briefly review the recently developed, Markov process based isothermal chemical thermodynamics for nonlinear, driven mesoscopic kinetic systems. Both the instantaneous Shannon entropy {\boldmath $S[p_{\alpha}(t)]$} and relative entropy…

Statistical Mechanics · Physics 2017-01-10 David B. Saakian , Hong Qian

This paper concerns a model for tumor cell migration through the surrounding extracellular matrix by considering mass balance phenomena involving the chemical interactions produced on the cell surface. The well-posedness of this model is…

Analysis of PDEs · Mathematics 2015-09-03 J. Nieto , L. Urrutia

Various biological system models have been proposed in systems biology, which are based on the complex biological reactions kinetic of various components. These models are not practical because we lack of kinetic information. In this paper,…

Quantitative Methods · Quantitative Biology 2011-02-19 Weidong Huang , Chundu Wu , Bingjia Xiao , Weidong Xia

Nonintegrability plays a crucial role in thermalization and transport processes in many-body Hamiltonian systems, yet its quantitative effects remain unclear. To reveal the connection between the macroscopic relaxation properties and the…

Statistical Mechanics · Physics 2023-10-20 Weicheng Fu , Zhen Wang , Yisen Wang , Yong Zhang , Hong Zhao

The gas dynamics under external force field is essentially associated with multiple scale nature due to the large variations of density and local Knudsen number. Single scale fluid dynamic equations, such as the Boltzmann and Navier-Stokes…

Fluid Dynamics · Physics 2017-10-31 Tianbai Xiao , Kun Xu , Qingdong Cai , Tiezheng Qian