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In a common experimental setting, the behaviour of a noisy dynamical system is monitored in response to manipulations of one or more control parameters. Here, we introduce a structured model to describe parametric changes in qualitative…

Dynamical Systems · Mathematics 2018-07-05 Gergo Bohner , Maneesh Sahani

A model's interpretability is essential to many practical applications such as clinical decision support systems. In this paper, a novel interpretable machine learning method is presented, which can model the relationship between input…

Machine Learning · Computer Science 2022-12-06 Heming Yao , Harm Derksen , Jessica R. Golbus , Justin Zhang , Keith D. Aaronson , Jonathan Gryak , Kayvan Najarian

We propose a data-assisted two-stage method for solving an inverse random source problem of the Helmholtz equation. In the first stage, the regularized Kaczmarz method is employed to generate initial approximations of the mean and variance…

Numerical Analysis · Mathematics 2024-03-05 Peijun Li , Ying Liang , Yuliang Wang

Quantifying how distinguishable two stochastic processes are lies at the heart of many fields, such as machine learning and quantitative finance. While several measures have been proposed for this task, none have universal applicability and…

Statistical Mechanics · Physics 2020-07-01 Chengran Yang , Felix C. Binder , Mile Gu , Thomas J. Elliott

A novel method to solve inverse problems for the wave equation is introduced. The method is a combination of the boundary control method and an iterative time reversal scheme, leading to adaptive imaging of coefficient functions of the wave…

Analysis of PDEs · Mathematics 2007-05-23 Kenrick Bingham , Yaroslav Kurylev , Matti Lassas , Samuli Siltanen

Temporal data such as time series can be viewed as discretized measurements of the underlying function. To build a generative model for such data we have to model the stochastic process that governs it. We propose a solution by defining the…

Machine Learning · Computer Science 2023-05-22 Marin Biloš , Kashif Rasul , Anderson Schneider , Yuriy Nevmyvaka , Stephan Günnemann

Many complex systems occurring in the natural or social sciences or economics are frequently described on a microscopic level, e.g., by lattice- or agent-based models. To analyze the states of such systems and their bifurcation structure on…

Adaptation and Self-Organizing Systems · Physics 2020-10-07 Clemens Willers , Uwe Thiele , Andrew J. Archer , David J. B. Lloyd , Oliver Kamps

In this paper we develop a perturbation method to predict the rate of occurrence of rare events for singularly perturbed stochastic systems using a probability density function approach. In contrast to a stochastic normal form approach, we…

Dynamical Systems · Mathematics 2015-06-16 Christoffer R. Heckman , Ira B. Schwartz

Synthetic control methods can produce misleading counterfactual predictions when outcome series contain unit-specific stochastic trends, a common feature of nonstationary macroeconomic data. Existing remedies, such as pre-filtering or…

Econometrics · Economics 2026-05-21 Ziyi Liu , Yiqing Xu

Inverse problems involve making inference about unknown parameters of a physical process using observational data. This paper investigates an important class of inverse problems -- the estimation of the initial condition of a…

Methodology · Statistics 2023-02-09 Xiao Liu , Kyongmin Yeo

We propose a data-driven method to learn the time-dependent probability density of a multivariate stochastic process from sample paths, assuming that the initial probability density is known and can be evaluated. Our method uses a novel…

Machine Learning · Statistics 2025-06-19 Agnimitra Dasgupta , Javier Murgoitio-Esandi , Ali Fardisi , Assad A Oberai

In this study, we present and analyze a novel variant of the stochastic gradient descent method, referred as Stochastic data-driven Bouligand Landweber iteration tailored for addressing the system of non-smooth ill-posed inverse problems.…

Functional Analysis · Mathematics 2024-02-08 Harshit Bajpai , Gaurav Mittal , Ankik Kumar Giri

We present a stochastic model of gait rhythm dynamics, based on transitions between different ``neural centers'', that reproduces distinctive statistical properties of normal human walking. By tuning one model parameter, the hopping range,…

Statistical Mechanics · Physics 2009-11-07 Yosef Ashkenazy , Jeffrey M. Hausdorff , Plamen Ch. Ivanov , Ary L. Goldberger , H. Eugene Stanley

The processing of ECG signal provides a wealth of information on cardiac function and overall cardiovascular health. While multi-lead ECG recordings are often necessary for a proper assessment of cardiac rhythms, they are not always…

Applications · Statistics 2016-11-23 Christophe L. Herry , Martin Frasch , Andrew JE Seely , Hau-tieng Wu

A new class of stochastic processes called independent and periodically identically distributed (i.p.i.d.) processes is defined to capture periodically varying statistical behavior. Algorithms are proposed to detect changes in such i.p.i.d.…

Statistics Theory · Mathematics 2018-10-31 Taposh Banerjee , Prudhvi Gurram , Gene Whipps

For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…

Molecular Networks · Quantitative Biology 2009-11-13 Matthew Scott , Terence Hwa , Brian Ingalls

This paper is concerned with classes of models of stochastic reaction dynamics with time-scales separation. We demonstrate that the existence of the time-scale separation naturally leads to the application of the averaging principle and…

Computational Physics · Physics 2007-05-23 Sergey Plyasunov

We develop a new tool, the time inhomogeneous Poisson equation in the whole space and with a terminal condition at infinity, to study the asymptotic behavior of the non-autonomous multi-scale stochastic system with irregular coefficients,…

Probability · Mathematics 2024-12-13 Ling Wang , Pengcheng Xia , Longjie Xie , Li Yang

Time-resolved single-cell omics data offers high-throughput, genome-wide measurements of cellular states, which are instrumental to reverse-engineer the processes underpinning cell fate. Such technologies are inherently destructive,…

Machine Learning · Computer Science 2026-02-04 Stephen Zhang , Suryanarayana Maddu , Xiaojie Qiu , Victor Chardès

We study the stochastic kinetics of a signaling module consisting of a two-state stochastic point process with negative feedback. In the active state, a product is synthesized which increases the active-to-inactive transition rate of the…

Quantitative Methods · Quantitative Biology 2007-08-09 Manoj Gopalakrishnan , Peter Borowski , Frank Jülicher , Martin Zapotocky