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Heterogeneity is a hallmark of all cancers. Tumor heterogeneity is found at different levels -- interpatient, intrapatient, and intratumor heterogeneity. All of them pose challenges for clinical treatments. The latter two scenarios can also…

Soft Condensed Matter · Physics 2020-04-03 Xin Li , D. Thirumalai

The theory of phase transitions is based on the consideration of "idealized" models, such as the Ising model: a system of magnetic moments living on a cubic lattice and having only two accessible states. For simplicity the interaction is…

Statistical Mechanics · Physics 2011-12-22 H Chamati , S Romano

Macroscopic theories of nucleation such as classical nucleation theory envision that clusters of the bulk stable phase form inside the bulk metastable phase. Molecular dynamics simulations are often used to elucidate nucleation mechanisms,…

Materials Science · Physics 2017-09-06 Bingqing Cheng , Michele Ceriotti

For a class of interacting particle systems in continuous space, we show that finite-volume approximations of the bulk diffusion matrix converge at an algebraic rate. The models we consider are reversible with respect to the Poisson…

Probability · Mathematics 2021-12-07 Arianna Giunti , Chenlin Gu , Jean-Christophe Mourrat

Motivated by unexpected morphologies of the emerging liquid phase (channels, bulges, droplets) at the edge of thin, melting alkane terraces, we propose a new heterogeneous nucleation pathway. The competition between bulk and interfacial…

Chemical Physics · Physics 2015-06-04 Halim Kusumaatmaja , Reinhard Lipowsky , Chenyu Jin , Radu-Cristian Mutihac , Hans Riegler

Studies of disordered heterogeneous media and galaxy cosmology share a common goal: analyzing the distribution of particles at `microscales' to predict physical properties at `macroscales', whether for a liquid, composite material, or…

Cosmology and Nongalactic Astrophysics · Physics 2023-01-11 Oliver H. E. Philcox , Salvatore Torquato

Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell…

Quantitative Methods · Quantitative Biology 2021-09-15 Niko Komin , Alexander Skupin

Nanochains of atoms, molecules and polymers have gained recent interest in the experimental sciences. This article contributes to an advanced mathematical modeling of the mechanical properties of nanochains that allow for heterogenities,…

Analysis of PDEs · Mathematics 2019-09-17 Laura Lauerbach , Stefan Neukamm , Mathias Schäffner , Anja Schlömerkemper

We study the time evolution of correlation functions in long-range interacting quantum Ising models. For a large class of initial conditions, exact analytic results are obtained in arbitrary lattice dimension, both for ferromagnetic and…

Quantum Physics · Physics 2013-08-07 Mauritz van den Worm , Brian C. Sawyer , John J. Bollinger , Michael Kastner

Homogeneous nucleation of a new phase near an Ising-like critical point of another phase transition is studied. A scaling analysis shows that the free energy barrier to nucleation contains a singular term with the same scaling as the order…

Statistical Mechanics · Physics 2009-11-07 Richard P. Sear

We redevelop persistent homology (topological persistence) from a categorical point of view. The main objects of study are diagrams, indexed by the poset of real numbers, in some target category. The set of such diagrams has an interleaving…

Algebraic Topology · Mathematics 2014-05-13 Peter Bubenik , Jonathan A. Scott

We study the difference between quantum and classical behavior in a pair of nonidentical cavities with second-harmonic generation. In the classical limit, each cavity has a limit-cycle solution, in which the photon number oscillates…

Quantum Physics · Physics 2013-09-04 Tony E. Lee , M. C. Cross

We investigate the form and stability of a cloud of atoms confined in a harmonic trap when the scattering length is negative. We find that, besides the known low density metastable solution, a new branch of Bose condensate appears at higher…

Condensed Matter · Physics 2009-10-31 Alberto Parola , Luca Salasnich , Luciano Reatto

We study the non-equilibrium dynamics of quenching through a quantum critical point in topological systems, focusing on one of their defining features: ground state degeneracies and associated topological sectors. We present the notion of…

Strongly Correlated Electrons · Physics 2014-07-02 G. Kells , D. Sen , J. K. Slingerland , S. Vishveshwara

The study of high energy collisions between heavy nuclei is a field unto itself, distinct from nuclear and particle physics. A defining aspect of heavy ion physics is the importance of a bulk, self-interacting system with a rich space-time…

Nuclear Theory · Physics 2016-08-24 Mike Lisa

The search for departures from standard hydrodynamics in many-body systems has yielded a number of promising leads, especially in low dimension. Here we study one of the simplest classical interacting lattice models, the nearest-neighbour…

Statistical Mechanics · Physics 2022-12-22 Adam J. McRoberts , Thomas Bilitewski , Masudul Haque , Roderich Moessner

An analytical model for the evolution of the boundary of the new phase in transformations ruled by nucleation and growth is presented. Both homogeneous and heterogeneous nucleation have been considered: The former includes transformations…

Materials Science · Physics 2020-08-26 Massimo Tomellini

We investigate the stationary and dynamic properties of the celebrated Nos\'e-Hoover dynamics of many-body interacting Hamiltonian systems, with an emphasis on the effect of inter-particle interactions. To this end, we consider a model…

Statistical Mechanics · Physics 2017-10-25 Shamik Gupta , Stefano Ruffo

The structure of finite nuclei is investigated by employing an interaction model which is based on the low-momentum interaction $V_{lowk}$. It is supplemented by a density-dependent contact interaction fitted to reproduce the saturation…

Nuclear Theory · Physics 2015-06-19 E. N. E. van Dalen , H. Müther

The correlated non-equilibrium dynamics of few-boson systems in one-dimensional finite lattices is investigated. Starting from weak interactions we perform a sudden interaction quench and employ the numerically exact Multi-Layer…

Quantum Gases · Physics 2017-10-31 S. I. Mistakidis , L. Cao , P. Schmelcher