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Single receptor-ligand bonds have finite lifetimes, so that biological systems can dynamically react to changes in their environment. In cell adhesion, adhesion bonds usually act cooperatively in adhesion clusters. Outside the cellular…

Soft Condensed Matter · Physics 2007-05-23 T. Erdmann , U. S. Schwarz

We solve the stochastic equations for a cluster of parallel bonds with shared constant loading, rebinding and the completely dissociated state as an absorbing boundary. In the small force regime, cluster lifetime grows only logarithmically…

Soft Condensed Matter · Physics 2007-05-23 T. Erdmann , U. S. Schwarz

Biological adhesion often involves several pairs of specific receptor-ligand molecules. Using rate equations, we study theoretically the rupture of such multiple parallel bonds under dynamic loading assisted by thermal activation. For a…

Biological Physics · Physics 2009-11-06 Udo Seifert

Adhesion interactions mediated by multiple bond types are relevant for many biological and soft matter systems, including the adhesion of biological cells and functionalized colloidal particles to various substrates. To elucidate advantages…

Biological Physics · Physics 2020-10-21 Anil K. Dasanna , Gerhard Gompper , Dmitry A. Fedosov

In biological materials, strong binding despite an applied load force is often based on clusters of dynamic bonds that share the load. Different macroscopic behaviors have been described depending on whether the load is shared locally or…

Biological Physics · Physics 2025-09-11 Yannick Lüdemann , Stefan Klumpp , Komal Bhattacharyya

We present a general stochastic dynamic model of a cluster of biological complexes with fluctuating dissociation and association rates. The master equation has analytical solutions in two limiting cases: the vanishing force with reflecting…

Soft Condensed Matter · Physics 2007-05-23 Fei Liu , Zhong-can Ou-Yang

The strength of a simple soft bond under constant loading rate is studied theoretically. We find a scaling regime where rebinding is negligible and the rupture force of the bond scales as $const. + (\ln (kv))^{2/3}$, where $kv$ is the…

Soft Condensed Matter · Physics 2007-05-23 Hsuan-Yi Chen , Yi-Ping Chu

We study the existence of distinct failure regimes in a model for fracture in fibrous materials. We simulate a bundle of parallel fibers under uniaxial static load and observe two different failure regimes: a catastrophic and a slowly…

Statistical Mechanics · Physics 2015-06-24 I. L. Menezes-Sobrinho , J. G. Moreira , A. T. Bernardes

We simulate the collision of atomic clusters with a weakly attractive surface using molecular dynamics in a regime between soft-landing and fragmentation, where the cluster undergoes large deformation but remains intact. As a function of…

Materials Science · Physics 2007-05-23 A. Awasthi , S. C. Hendy , P. Zoontjens , S. A. Brown

We consider the rupture dynamics of a homopolymer chain pulled at one end at a constant loading rate r. Compared to single bond breaking, the existence of the chain introduces two new aspects into rupture dynamics: the non-Markovian aspect…

Soft Condensed Matter · Physics 2009-10-29 S. Fugmann , I. M. Sokolov

The geometry of fracture patterns in a dilute elastic network is explored using molecular dynamics simulation. The network in two dimensions is subjected to a uniform strain which drives the fracture to develop by the growth and coalescence…

Condensed Matter · Physics 2015-06-25 P. Ray , G. Date

We present results of simulations for a dilute gas of inelastically colliding particles. Collisions are modelled as a stochastic process, which on average decreases the translational energy (cooling), but allows for fluctuations in the…

Statistical Mechanics · Physics 2009-10-30 Timo Aspelmeier , Götz Giese , Annette Zippelius

The random-cluster model, a correlated bond percolation model, unifies a range of important models of statistical mechanics in one description, including independent bond percolation, the Potts model and uniform spanning trees. By…

Statistical Mechanics · Physics 2016-01-28 Eren Metin Elçi , Martin Weigel , Nikolaos G. Fytas

We investigate a class of stochastic aggregation processes involving two types of clusters: active and passive. The mass distribution is obtained analytically for several aggregation rates. When the aggregation rate is constant, we find…

Statistical Mechanics · Physics 2007-05-23 P. L. Krapivsky , E. Ben-Naim

The structure and mechanical properties of a simple two-dimensional model of a cohesive powder are investigated by molecular dynamics simulations. Micromechanical ingredients involve elasticity, friction, a short range attraction and,…

Disordered Systems and Neural Networks · Physics 2007-05-24 Francisco Gilabert , Jean-Noel Roux , Antonio Castellanos

We study the creep rupture of bundles of viscoelastic fibers occurring under uniaxial constant tensile loading. A novel fiber bundle model is introduced which combines the viscoelastic constitutive behaviour and the strain controlled…

Statistical Mechanics · Physics 2019-05-15 Raul Cruz Hidalgo , Ferenc Kun , Hans. J. Herrmann

The compressive yield stress of particle gels shows a highly nonlinear dependence on the packing fraction. We have studied continuous compression processes, and discussed the packing fraction dependence with the particle scale…

Soft Condensed Matter · Physics 2013-11-22 Ryohei Seto , Robert Botet , Martine Meireles , Günter K. Auernhammer , Bernard Cabane

It is shown that a compound elastic structure, which displays a dynamic instability, may be designed as the union (or 'fusion') of two structures which are stable when separately analyzed. The compound elastic structure has two degrees of…

Classical Physics · Physics 2023-01-16 Marco Rossi , Andrea Piccolroaz , Davide Bigoni

The quasistatic behavior of a simple 2D model of a cohesive powder under isotropic loads is investigated by Discrete Element simulations. The loose packing states, as studied in a previous paper, undergo important structural changes under…

Materials Science · Physics 2008-10-27 Francisco Gilabert , Jean-Noël Roux , Antonio Castellanos

We consider a microscopic model for the failure of soft adhesives in tension based on ideas of bond rupture under dynamic loading. Focusing on adhesive failure under loading at constant velocity, we demonstrate that bi-modal curves of…

Soft Condensed Matter · Physics 2007-05-23 Dominic Vella , L. Mahadevan
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