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We present a two channel driven lattice gas model with oppositely directed species moving on two parallel lanes with lane switching processes. We study correlated lane switching mechanism for particles so that switching may occur with…

Statistical Mechanics · Physics 2015-05-28 Sudipto Muhuri , Ignacio Pagonabarraga

The transport by molecular motors along cytoskeletal filaments is studied theoretically in the presence of static defects. The movements of single motors are described as biased random walks along the filament as well as binding to and…

Biological Physics · Physics 2009-05-08 Yan Chai , Reinhard Lipowsky , Stefan Klumpp

We introduce a stochastic lattice gas model including two particle species and two parallel lanes. One lane with exclusion interaction and directed motion and the other lane without exclusion and unbiased diffusion, mimicking a micotubule…

Statistical Mechanics · Physics 2009-11-13 M. Ebbinghaus , L. Santen

Cytoskeletal motor proteins are involved in major intracellular transport processes which are vital for maintaining appropriate cellular function. The motor exhibits distinct states of motility: active motion along filaments, and…

Biological Physics · Physics 2016-11-29 Anne E. Hafner , Ludger Santen , Heiko Rieger , M. Reza Shaebani

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

Statistical Mechanics · Physics 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky

We study a two filament driven lattice gas model with oppositely directed species of particles moving on two parallel filaments with filament switching processes and particle inflow and outflow at filament ends. The filament switching…

Soft Condensed Matter · Physics 2017-03-08 Subhadip Ghosh , Ignacio Pagonabarraga , Sudipto Muhuri

The traffic of molecular motors through open tube-like compartments is studied using lattice models. These models exhibit boundary-induced phase transitions related to those of the asymmetric simple exclusion process (ASEP) in one…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

The stationary states of systems with many molecular motors are studied theoretically for uniaxial and centered (aster-like) arrangements of cytoskeletal filaments using Monte Carlo simulations and a two-state model. Mutual exclusion of…

Subcellular Processes · Quantitative Biology 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

We study a two-lane driven lattice gas model with oppositely directed particles moving on two periodic lanes with correlated lane switching processes, so that particles can switch lanes with finite probability only when oppositely directed…

Statistical Mechanics · Physics 2015-06-18 Sudipto Muhuri

Molecular motors interacting with cytoskeletal filaments undergo peculiar random walks consisting of alternating sequences of directed movements along the filaments and diffusive motion in the surrounding solution. An ensemble of motors is…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

The dynamics of two groups of molecular motors pulling in opposite directions on a rigid filament is studied theoretically. To this end we first consider the behavior of one set of motors pulling in a single direction against an external…

Subcellular Processes · Quantitative Biology 2015-05-13 Daniel Hexner , Yariv Kafri

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

Statistical Mechanics · Physics 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

We study three different lattice models in which two species of diffusing particles are driven in opposite directions by an electric field. We focus on dynamical phase transitions that involve phase separation into domains that may be…

Statistical Mechanics · Physics 2022-09-15 Honghao Yu , Kristian Thijssen , Robert L. Jack

The traffic of molecular motors which interact through mutual exclusion is studied theoretically for half-open tube-like compartments. These half-open tubes mimic the shapes of axons. The mutual exclusion leads to traffic jams or density…

Statistical Mechanics · Physics 2007-05-23 Melanie J. I. Muller , Stefan Klumpp , Reinhard Lipowsky

The flow of motor proteins on a filamental track is modelled within the the framework of lattice driven diffusive systems. Motors, considered as hopping particles, perform a highly biased asymmetric exclusion process when bound to the…

Statistical Mechanics · Physics 2007-05-23 M. Ebrahim Fouladvand , Modjtaba Salehi , Mostafa Yadegari

Active motion of molecules along filamentous structures is a crucial feature of cell biology and is often modeled with the paradigmatic asymmetric simple exclusion process. Motivated by recent experimental studies that have addressed the…

Statistical Mechanics · Physics 2018-09-19 Patrick Wilke , Emanuel Reithmann , Erwin Frey

Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models.…

Soft Condensed Matter · Physics 2009-11-13 Max N. Artyomov , Alexander Yu. Morozov , Anatoly B. Kolomeisky
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