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In the mammalian nervous system, various synaptic plasticity rules act, either individually or synergistically, and over wide-ranging timescales to dictate the processes that enable learning and memory formation. To mimic biological…

Disordered Systems and Neural Networks · Physics 2021-06-11 Syed Ghazi Sarwat , Benedikt Kersting , Timoleon Moraitis , Vara Prasad Jonnalagadda , Abu Sebastian

To learn useful dynamics on long time scales, neurons must use plasticity rules that account for long-term, circuit-wide effects of synaptic changes. In other words, neural circuits must solve a credit assignment problem to appropriately…

Neurons and Cognition · Quantitative Biology 2019-05-30 Owen Marschall , Kyunghyun Cho , Cristina Savin

The brain has the phenomenal ability to reorganize itself by forming new connections among neurons and by pruning others. The so-called neural or brain plasticity facilitates the modification of brain structure and function over different…

We propose a design principle for the learning circuits of the biological brain. The principle states that almost any dendritic weights updated via heterosynaptic plasticity can implement a generalized and efficient class of gradient-based…

Neurons and Cognition · Quantitative Biology 2025-05-06 Liu Ziyin , Isaac Chuang , Tomaso Poggio

Neural circuits exhibit remarkable computational flexibility, enabling adaptive responses to noisy and ever-changing environmental cues. A fundamental question in neuroscience concerns how a wide range of behaviors can emerge from a…

Statistical Mechanics · Physics 2025-09-18 Giacomo Barzon , Daniel M. Busiello , Giorgio Nicoletti

Learning, especially rapid learning, is critical for survival. However, learning is hard: a large number of synaptic weights must be set based on noisy, often ambiguous, sensory information. In such a high-noise regime, keeping track of…

Neurons and Cognition · Quantitative Biology 2021-03-22 Laurence Aitchison , Jannes Jegminat , Jorge Aurelio Menendez , Jean-Pascal Pfister , Alex Pouget , Peter E. Latham

Bayesian inference provides a principled framework for understanding brain function, while neural activity in the brain is inherently spike-based. This paper bridges these two perspectives by designing spiking neural networks that simulate…

Neurons and Cognition · Quantitative Biology 2026-01-01 Sepideh Adamiat , Wouter M. Kouw , Bert de Vries

Hebbian meta-learning has recently shown promise to solve hard reinforcement learning problems, allowing agents to adapt to some degree to changes in the environment. However, because each synapse in these approaches can learn a very…

Neural and Evolutionary Computing · Computer Science 2021-06-24 Rasmus Berg Palm , Elias Najarro , Sebastian Risi

We study associative memory neural networks based on the Hodgkin-Huxley type of spiking neurons. We introduce the spike-timing-dependent learning rule, in which the time window with the negative part as well as the positive part is used to…

Disordered Systems and Neural Networks · Physics 2009-11-07 Masahiko Yoshioka

Spike-timing dependent plasticity (STDP) which observed in the brain has proven to be important in biological learning. On the other hand, artificial neural networks use a different way to learn, such as Back-Propagation or Contrastive…

Neural and Evolutionary Computing · Computer Science 2021-06-10 Shiyuan Li

In machine learning, error back-propagation in multi-layer neural networks (deep learning) has been impressively successful in supervised and reinforcement learning tasks. As a model for learning in the brain, however, deep learning has…

Machine Learning · Computer Science 2016-12-19 Thomas Mesnard , Wulfram Gerstner , Johanni Brea

Memory is a key component of biological neural systems that enables the retention of information over a huge range of temporal scales, ranging from hundreds of milliseconds up to years. While Hebbian plasticity is believed to play a pivotal…

Neural and Evolutionary Computing · Computer Science 2022-05-24 Thomas Limbacher , Ozan Özdenizci , Robert Legenstein

In neural circuits, synaptic strengths influence neuronal activity by shaping network dynamics, and neuronal activity influences synaptic strengths through activity-dependent plasticity. Motivated by this fact, we study a recurrent-network…

Neurons and Cognition · Quantitative Biology 2024-01-12 David G. Clark , L. F. Abbott

Inspired by the natural nervous system, synaptic plasticity rules are applied to train spiking neural networks with local information, making them suitable for online learning on neuromorphic hardware. However, when such rules are…

Neural and Evolutionary Computing · Computer Science 2022-02-28 J. Lu , J. J. Hagenaars , G. C. H. E. de Croon

Neural populations exposed to a certain stimulus learn to represent it better. However, the process that leads local, self-organized rules to do so is unclear. We address the question of how can a neural periodic input be learned and use…

Neurons and Cognition · Quantitative Biology 2020-06-16 Pau Vilimelis Aceituno

Experiments have shown that the same stimulation pattern that causes Long-Term Potentiation in proximal synapses, will induce Long-Term Depression in distal ones. In order to understand these, and other, surprising observations we use a…

Neurons and Cognition · Quantitative Biology 2020-11-20 Claire Meissner-Bernard , Matthias Tsai , Laureline Logiaco , Wulfram Gerstner

This review explores biologically inspired learning as a model for intelligent robot control and sensing technology on the basis of specific examples. Hebbian synaptic learning is discussed as a functionally relevant model for machine…

Robotics · Computer Science 2022-02-28 Birgitta Dresp-Langley

Synaptic plasticity seems to be a capital aspect of the dynamics of neural networks. It is about the physiological modifications of the synapse, which have like consequence a variation of the value of the synaptic weight. The information…

Computer Vision and Pattern Recognition · Computer Science 2012-09-25 Tarek Behi , Najet Arous , Noureddine Ellouze

Synaptic plasticity or the ability of a brain to changes one or more of its functions or structures has generated and is sill generating a lot of interest from the scientific community especially neuroscientists. These interests especially…

Neurons and Cognition · Quantitative Biology 2022-03-28 Eddy Kwessi

We study a learning rule based upon the temporal correlation (weighted by a learning kernel) between incoming spikes and the internal state of the postsynaptic neuron, building upon previous studies of spike timing dependent synaptic…

Neurons and Cognition · Quantitative Biology 2007-05-23 Juergen Jost