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We consider the dynamics of bodies with "active" microstructure described by vector-valued phase fields. For waves with time-varying amplitude, the associated evolution equation involves a matrix that can be non-normal, depending on the…

Mathematical Physics · Physics 2025-02-18 Michele Benzi , Daniele La Pegna , Paolo Maria Mariano

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

Statistical models provide a powerful and useful class of approximations for calculating reaction rates by bypassing the need for detailed, and often difficult, dynamical considerations. Such approaches invariably invoke specific…

Chemical Physics · Physics 2020-04-01 Sourav Karmakar , Pankaj Kumar Yadav , Srihari Keshavamurthy

Multistationarity in biological systems is a mechanism of cellular decision making. In particular, signaling pathways regulated by protein phosphorylation display features that facilitate a variety of responses to different biological…

Subcellular Processes · Quantitative Biology 2011-07-05 Elisenda Feliu , Carsten Wiuf

Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell…

Quantitative Methods · Quantitative Biology 2021-09-15 Niko Komin , Alexander Skupin

We study the dynamical stability and fates of hierarchical (in semi-major axis) two-planet systems with arbitrary eccentricities and mutual inclinations. We run a large number of long-term numerical integrations and use the Support Vector…

Earth and Planetary Astrophysics · Physics 2015-08-06 Cristobal Petrovich

In order to analyze the effect of chaos or order on the rate of decoherence in a subsystem we aim to distinguish effects of the two types of dynamics from those depending on the choice of the wave packet. To isolate the former we introduce…

Chaotic Dynamics · Physics 2007-05-23 T. Gorin , T. H. Seligman

Robustness to perturbation is a key topic in the study of complex systems occurring across a wide variety of applications from epidemiology to biochemistry. Here we analyze the eigenspectrum of the Jacobian matrices associated to a general…

Adaptation and Self-Organizing Systems · Physics 2025-12-11 Shraosi Dawn , Subrata Ghosh , Chandrakala Meena , Tim Rogers , Chittaranjan Hens

In this paper we consider a variety of procedures for numerical statistical inference in the family of univariate and multivariate stable distributions. In connection with univariate distributions (i) we provide approximations by finite…

Computation · Statistics 2012-09-04 Efthymios G. Tsionas

Oscillatory dynamics are ubiquitous in biological networks. Possible sources of oscillations are well understood in low-dimensional systems, but have not been fully explored in high-dimensional networks. Here we study large networks…

Disordered Systems and Neural Networks · Physics 2016-12-21 Célian Bimbard , Erwan Ledoux , Srdjan Ostojic

Examining individual components of cellular systems has been successful in uncovering molecular reactions and interactions. However, the challenge lies in integrating these components into a comprehensive system-scale map. This difficulty…

Other Quantitative Biology · Quantitative Biology 2024-07-03 Nima Dehghani

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Phase separations in strongly coupled fine particles in plasmas are discussed and two-component mixtures are simulated by molecular dynamics with the background plasma being treated as continuum. The system size of laboratory experiments is…

Plasma Physics · Physics 2024-05-24 Hiroo Totsuji

Stochastic fluctuations of molecule numbers are ubiquitous in biological systems. Important examples include gene expression and enzymatic processes in living cells. Such systems are typically modelled as chemical reaction networks whose…

Quantitative Methods · Quantitative Biology 2017-01-13 David Schnoerr , Guido Sanguinetti , Ramon Grima

The morphology of a growing crystal surface is studied in the case of an unstable two-dimensional step flow. Competition between bunching and meandering of steps leads to a variety of patterns characterized by their respective instability…

Statistical Mechanics · Physics 2012-07-19 A. Verga

Through extensive studies of dynamical system modeling cellular growth and reproduction, we find evidence that complexity arises in multicellular organisms naturally through evolution. Without any elaborate control mechanism, these systems…

Adaptation and Self-Organizing Systems · Physics 2009-10-31 Chikara Furusawa , Kunihiko Kaneko

The network of biochemical reactions inside living organisms is characterized by an overwhelming complexity which stems from the sheer number of reactions and from the complicated topology of biochemical cycles. However the high speed of…

Biological Physics · Physics 2009-10-30 Edoardo Milotti , Alessio Del Fabbro , Roberto Chignola

Partitioning of (bio)materials in polymeric mixtures is a key phenomenon both in cellular environments, as well as in industrial applications. In cells, several macromolecules are suspended within different biomolecular phases. On the other…

Soft Condensed Matter · Physics 2025-10-15 Vikki Anand Varma , Alberto Scacchi

We develop a monitoring procedure to detect changes in a large approximate factor model. Letting $r$ be the number of common factors, we base our statistics on the fact that the $\left( r+1\right) $-th eigenvalue of the sample covariance…

Methodology · Statistics 2022-02-03 Matteo Barigozzi , Lorenzo Trapani

In this paper, we mainly study the robust stability of linear continuous systems with parameter uncertainties, a more general kind of uncertainties for system matrices is considered, i.e., entries of system matrices are rational functions…

Symbolic Computation · Computer Science 2010-03-17 Xiaorong Hou , Junwei Shao