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Energy functions for pure and heterogenous systems are one of the backbones for molecular simulation of condensed phase systems. With the advent of machine learned potential energy surfaces (ML-PESs) a new era has started. Statistical…

We introduce the well-tempered ensemble (WTE) which is the biased ensemble sampled by well-tempered metadynamics when the energy is used as collective variable. WTE can be designed so as to have approximately the same average energy as the…

Statistical Mechanics · Physics 2015-05-14 M. Bonomi , M. Parrinello

Algorithms for simulating complex physical systems or solving difficult optimization problems often resort to an annealing process. Rather than simulating the system at the temperature of interest, an annealing algorithm starts at a…

Computational Physics · Physics 2015-04-02 Michael Habeck

We model a planar array of fluxlines as a discrete solid-on-solid model with quenched disorder. Simulations at finite temperatures are made possible by a new algorithm which circumvents the slow glassy dynamics encountered by traditional…

Disordered Systems and Neural Networks · Physics 2009-10-31 Chen Zeng , Paul L. Leath , Terence Hwa

We introduce a new update scheme to systematically improve the efficiency of parallel tempering simulations. We show that by adapting the number of sweeps between replica exchanges to the canonical autocorrelation time, the average…

Statistical Mechanics · Physics 2008-09-26 Elmar Bittner , Andreas Nussbaumer , Wolfhard Janke

We present generalized-ensemble algorithms for isobaric-isothermal molecular simulations. In addition to the multibaric-multithermal algorithm and replica-exchange method for the isobaric-isothermal ensemble, which have already been…

Statistical Mechanics · Physics 2010-04-14 Yoshiharu Mori , Yuko Okamoto

Recently, Velazquez and Curilef have proposed a methodology to extend Monte Carlo algorithms based on canonical ensemble, which is aimed to overcome slow sampling problems associated with temperature-driven discontinuous phase transitions.…

Statistical Mechanics · Physics 2013-07-31 L. Velazquez , J. C. Castro-Palacio

We consider sampling from a Gibbs distribution by evolving finitely many particles. We propose a preconditioned version of a recently proposed noise-free sampling method, governed by approximating the score function with the numerically…

Machine Learning · Statistics 2026-05-18 Hong Ye Tan , Stanley Osher , Wuchen Li

In this paper, we present a modelling experiment developed to study systems of cities and processes of urbanisation in large territories over long time spans. Building on geographical theories of urban evolution, we rely on agent-based…

Umbrella sampling efficiently yields equilibrium averages that depend on exploring rare states of a model by biasing simulations to windows of coordinate values and then combining the resulting data with physical weighting. Here, we…

Statistical Mechanics · Physics 2016-09-21 Erik Thiede , Brian Van Koten , Jonathan Weare , Aaron R. Dinner

We demonstrate how a prior assumption of smoothness can be used to enhance the reconstruction of free energy profiles from multiple umbrella sampling simulations using the Bayesian Gaussian process regression approach. The method we derive…

Statistical Mechanics · Physics 2014-07-25 Noam Bernstein , Thomas Stecher , Gábor Csányi

In systems characterized by a rough potential energy landscape, local energetic minima and saddles define a network of metastable states whose topology strongly influences the dynamics. Changes in temperature, causing the merging and…

Soft Condensed Matter · Physics 2009-07-24 Marco Baiesi , Lorenzo Bongini , Lapo Casetti , Lorenzo Tattini

In this chapter we provide a thorough overview of the use of energy-based models (EBMs) in the context of inverse imaging problems. EBMs are probability distributions modeled via Gibbs densities $p(x) \propto \exp{-E(x)}$ with an…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Andreas Habring , Martin Holler , Thomas Pock , Martin Zach

Gibbs sampling is a crucial computational technique used in physics, statistics, and many other scientific fields. For classical Hamiltonians, the most commonly used Gibbs sampler is the Metropolis algorithm, known for having the Gibbs…

Quantum Physics · Physics 2024-06-25 Jiaqing Jiang , Sandy Irani

The free energetics of water density fluctuations in bulk water, at interfaces, and in hydrophobic confinement inform the hydration of hydrophobic solutes as well as their interactions and assembly. The characterization of such free…

Statistical Mechanics · Physics 2018-03-15 Erte Xi , Sean M. Marks , Suruchi Fialoke , Amish J. Patel

In recent years, pi-conjugated polymers are attracting considerable interest in view of their light-dependent torsional reorganization around the pi-conjugated backbone, which determines peculiar light-emitting properties. Motivated by the…

Chemical Physics · Physics 2021-05-19 Mariagrazia Fortino , Concetta Cozza , Massimiliano Bonomi , Adriana Pietropaolo

Phase diagrams serve as a highly informative tool for materials design, encapsulating information about the phases that a material can manifest under specific conditions. In this work, we develop a method in which Bayesian inference is…

Materials Science · Physics 2023-09-06 Timofei Miryashkin , Olga Klimanova , Vladimir Ladygin , Alexander Shapeev

We construct a simple quantum version of the classical Metropolis algorithm to prepare and observe quantum thermal states. It induces both a quantum Markov chain that mixes the quantum thermal state and a classical Markov chain that mixes…

Quantum Physics · Physics 2022-06-10 Jonathan E. Moussa

It is widely accepted that the dynamic of entanglement in presence of a generic circuit can be predicted by the knowledge of the statistical properties of the entanglement spectrum. We tested this assumption by applying a Metropolis-like…

Quantum Physics · Physics 2023-09-20 J. Odavić , G. Torre , N. Mijić , D. Davidović , F. Franchini , S. M. Giampaolo

Metadynamics (MTD) is a very powerful technique to sample high-dimensional free energy landscapes, and due to its self-guiding property, the method has been successful in studying complex reactions and conformational changes. MTD sampling…

Computational Physics · Physics 2016-02-05 Shalini Awasthi , Venkat Kapil , Nisanth N. Nair