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We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models…

Cellular Automata and Lattice Gases · Physics 2025-01-09 Pascal R. Buenzli , Shahak Kuba , Ryan J. Murphy , Matthew J. Simpson

We investigate the strong curvature that appears at the boundaries of a thin crumpled elastic membrane. We account for these high-curvature regions in terms of the stretching-ridge singularity believed to dominate the structure of strongly…

Soft Condensed Matter · Physics 2008-11-23 T. A. Witten

Critical lateral pressure for a pore formation and phase diagram of porous membrane are derived analytically as functions of the microscopic parameters of the lipid chains. The derivation exploits path-integral calculation of the free…

Soft Condensed Matter · Physics 2015-06-18 S. I. Mukhin , B. B. Kheyfets

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

Soft Condensed Matter · Physics 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan

An arbitrary Lagrangian--Eulerian finite element method and numerical implementation for curved and deforming lipid membranes is presented here. The membrane surface is endowed with a mesh whose in-plane motion need not depend on the…

Computational Physics · Physics 2026-02-24 Amaresh Sahu

An integrated mechanical model for fiber-laden membranes is presented and representative predictions of relevance to cellulose ordering and orientation in the plant cell wall are presented. The model describes nematic liquid crystalline…

Biological Physics · Physics 2009-06-24 Y. K. Murugesan , A. D. Rey

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

The thermodynamics and mechanics of the surface of a deformable body are studied here, following and refining the general approach of Gibbs. It is first shown that the 'local' thermodynamic variables of the state of the surface are only the…

Statistical Mechanics · Physics 2019-06-27 Juan Olives

Whether live cell membranes show miscibility phase transitions (MPTs), and if so, how they fluctuate near the transitions remain outstanding unresolved issues in physics and biology alike. Motivated by these questions we construct a generic…

Soft Condensed Matter · Physics 2017-12-01 Tirthankar Banerjee , Abhik Basu

Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they…

Biological Physics · Physics 2019-03-15 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

The 'n-equivalences' of boundary conditions of lattice models are introduced and it is derived that the models with n-equivalent boundary conditions result in the identical free energy. It is shown that the free energy of the six-vertex…

Statistical Mechanics · Physics 2009-11-11 Kazuhiko Minami

We consider a coupled bulk-surface system of partial differential equations with nonlinear coupling modelling receptor-ligand dynamics. The model arises as a simplification of a mathematical model for the reaction between cell surface…

Analysis of PDEs · Mathematics 2016-11-08 Charles M. Elliott , Thomas Ranner , Chandrasekhar Venkataraman

Coarse-grained continuous descriptions for lipid bilayers are typically based on minimizing the Helfrich energy. Such models consider the fluid properties of these structures only implicitly and have been shown to nicely reproduce…

Soft Condensed Matter · Physics 2026-04-29 Ingo Nitschke , Jan Magnus Sischka , Axel Voigt

Contents: 1. Introduction 2. Amphiphilic molecules and the phases they form 3. Isolated membranes: the Helfrich hamiltonian 4. Vesicle shapes 5. Shape fluctuations in vesicles 6. Interacting fluid membranes 7. Conclusions A. Differential…

Condensed Matter · Physics 2016-08-31 Luca Peliti

In [12], the authors studied a particular class of equilibrium solutions of the Helfrich energy which satisfy a second order condition called the reduced membrane equation. In this paper we develop and apply a second variation formula for…

Differential Geometry · Mathematics 2024-01-11 Bennett Palmer , Alvaro Pampano

We consider surfaces with boundary satisfying a sixth order nonlinear elliptic partial differential equation corresponding to extremising the $L^2$-norm of the gradient of the mean curvature. We show that such surfaces with small $L^2$-norm…

Differential Geometry · Mathematics 2018-12-13 James McCoy , Glen Wheeler

Recent developments in lipid membrane models for simulations are reviewed. To reduce computational costs, various coarse-grained molecular models have been proposed. Among them, implicit solvent (solvent-free) molecular models are…

Soft Condensed Matter · Physics 2015-05-13 Hiroshi Noguchi

Particles bound to an interface interact because they deform its shape. The stresses that result are fully encoded in the geometry and described by a divergence-free surface stress tensor. This stress tensor can be used to express the force…

Soft Condensed Matter · Physics 2007-05-23 Martin Michael Mueller , Markus Deserno , Jemal Guven

We propose models in nonlinear elasticity for nonsimple materials that include surface energy terms. Additionally, we also discuss living surface loads on the boundary. We establish corresponding linearized models and show their…

Analysis of PDEs · Mathematics 2024-12-05 Martin Kružík , Edoardo Mainini

The dynamics of the development of instability of the free surface of liquid helium, which is charged by electrons localized above it, is studied. It is shown that, if the charge completely screens the electric field above the surface and…

Fluid Dynamics · Physics 2007-05-23 Nikolay M. Zubarev
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