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Several experiments show that the three dimensional (3D) organization of chromosomes affects genetic processes such as transcription and gene regulation. To better understand this connection, researchers developed the Hi-C method that is…

Genomics · Quantitative Biology 2019-05-03 Sang Hoon Lee , Yeonghoon Kim , Sungmin Lee , Xavier Durang , Per Stenberg , Jae-Hyung Jeon , Ludvig Lizana

Analysis of higher-order organizations, usually small connected subgraphs called motifs, is a fundamental task on complex networks. This paper studies a new problem of testing higher-order clusterability: given query access to an undirected…

Data Structures and Algorithms · Computer Science 2023-10-09 Yifei Li , Donghua Yang , Jianzhong Li

This paper proposes a new linearized mixed data sampling (MIDAS) model and develops a framework to infer clusters in a panel regression with mixed frequency data. The linearized MIDAS estimation method is more flexible and substantially…

Econometrics · Economics 2021-02-04 Yeonwoo Rho , Yun Liu , Hie Joo Ahn

Traditionally, the Dirichlet-multinomial distribution has been recognized as a key model for contingency tables generated by cluster sampling schemes. There are, however, other possible distributions appropriate for these contingency…

Methodology · Statistics 2016-09-26 Juana M. Alonso-Revenga , Nirian Martin , Leandro Pardo

We examine the structure of the percolating cluster (PC) formed by site percolation on a random clustered network (RCN) model. Using the generating functions, we formulate the clustering coefficient and assortative coefficient of the PC. We…

Physics and Society · Physics 2020-06-23 Takehisa Hasegawa , Shogo Mizutaka

Summary: Most cellular tasks are performed not by individual proteins, but by groups of functionally associated proteins, often referred to as modules. In a protein assocation network modules appear as groups of densely interconnected…

Molecular Networks · Quantitative Biology 2007-05-23 Balazs Adamcsek , Gergely Palla , Illes J. Farkas , Imre Derenyi , Tamas Vicsek

Unsupervised learning on high-dimensional RNA-seq data can reveal molecular subtypes beyond standard labels. We combine an autoencoder-based representation with clustering and stability analysis to search for rare but reproducible genomic…

Machine Learning · Computer Science 2025-11-18 Alaa Mezghiche

Spectral clustering and co-clustering are well-known techniques in data analysis, and recent work has extended spectral clustering to square, symmetric tensors and hypermatrices derived from a network. We develop a new tensor spectral…

Social and Information Networks · Computer Science 2016-03-02 Tao Wu , Austin R. Benson , David F. Gleich

Traditional clustering methods are limited when dealing with huge and heterogeneous groups of gene expression data, which motivates the development of bi-clustering methods. Bi-clustering methods are used to mine bi-clusters whose subsets…

Computer Vision and Pattern Recognition · Computer Science 2020-05-13 Kaijie Xu , Witold Pedrycz , Zhiwu Li , Yinghui Quan , Weike Nie

The next generation of data-intensive surveys are bound to produce a vast amount of data, which can be dealt with using machine-learning methods to explore possible correlations within the multi-dimensional parameter space. We explore the…

Research on the localization of the genetic basis associated with diseases or traits has been widely conducted in the last a few decades. Scan methods have been developed for region-based analysis in whole-genome association studies,…

Methodology · Statistics 2024-10-31 Wei Zhang , Fan Wang , Fang Yao

We present a new cluster detection algorithm designed for the Panoramic Survey Telescope and Rapid Response System (Pan-STARRS) survey but with generic application to any multiband data. The method makes no prior assumptions about the…

Cosmology and Nongalactic Astrophysics · Physics 2015-05-30 D. N. A. Murphy , J. E Geach , R. G. Bower

This paper introduces a novel technique to track structures in time varying graphs. The method uses a maximum a posteriori approach for adjusting a three-dimensional co-clustering of the source vertices, the destination vertices and the…

Machine Learning · Statistics 2016-08-30 Romain Guigourès , Marc Boullé , Fabrice Rossi

We present a large X-ray selected serendipitous cluster survey based on a novel joint analysis of archival Chandra and XMM-Newton data. The survey provides enough depth to reach clusters of flux of $\approx 10^{-14} {ergs} {cm}^{-2}…

Cosmology and Nongalactic Astrophysics · Physics 2014-11-20 J. R. Peterson , J. G. Jernigan , R. R. Gupta , J. Bankert , S. M. Kahn

We uncover the global organization of clustering in real complex networks. As it happens with other fundamental properties of networks such as the degree distribution, we find that real networks are neither completely random nor ordered…

A common approach for moving objects segmentation in a scene is to perform a background subtraction. Several methods have been proposed in this domain. However, they lack the ability of handling various difficult scenarios such as…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Long Ang Lim , Hacer Yalim Keles

We showed in this paper that similarity network can be used as an powerful tools to study the relationship of tRNA genes. We constructed a network of 3719 tRNA gene sequences using simplest alignment and studied its topology, degree…

Molecular Networks · Quantitative Biology 2009-09-29 Fangping Wei , Sheng Li , Hongru Ma

Genome sequencing technology has improved significantly in few last years and resulted in abundance genetic data. Artificial intelligence has been employed to analyze genetic data in response to its sheer size and variability. Gene…

Genomics · Quantitative Biology 2023-03-17 Muhammad Anwari Leksono , Ayu Purwarianti

The generation of protein crystals is necessary for the study of protein molecular function and structure. This is done empirically by processing large numbers of crystallization trials and inspecting them regularly in search of those with…

Computer Vision and Pattern Recognition · Computer Science 2018-05-15 Soheil Ghafurian , Peter Orth , Corey Strickland , Hua Su , Sangita Patel , Steven Soisson , Belma Dogdas

This paper introduces a method for studying the correlation structure of a range of responses modelled by a multivariate generalised linear mixed model (MGLMM). The methodology requires the existence of clusters of observations and that…

Methodology · Statistics 2021-08-02 Jeanett S. Pelck , Rodrigo Labouriau