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Related papers: On the Aging Dynamics in an Immune Network Model

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In this paper, we review the general features of the out-of-equilibrium dynamics of spin glasses. We use this example as a guideline for a brief description of glassy dynamics in other disordered systems like structural and polymer glasses,…

Disordered Systems and Neural Networks · Physics 2009-11-03 Eric Vincent

We investigate aging in glassy systems based on a simple model, where a point in configuration space performs thermally activated jumps between the minima of a random energy landscape. The model allows us to show explicitly a subaging…

Statistical Mechanics · Physics 2009-10-31 Bernd Rinn , Philipp Maass , Jean-Philippe Bouchaud

Complex network dynamics have been analyzed with models of systems of coupled switches or systems of coupled oscillators. However, many complex systems are composed of components with diverse dynamics whose interactions drive the system's…

Quantitative Methods · Quantitative Biology 2012-01-09 Matthew R. Francis , Elana J. Fertig

Self-adaptive dynamics occurs in many physical systems such as socio-economics, neuroscience, or biophysics. We formalize a self-adaptive modeling approach, where adaptation takes place within a set of strategies based on the history of the…

Adaptation and Self-Organizing Systems · Physics 2022-04-01 Konstantin Clauß , Christian Kuehn

The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Examples of such systems include DNA-functionalized colloids as well as nanoparticles grafted with antibodies to cell membrane…

Soft Condensed Matter · Physics 2007-05-23 Nicholas A. Licata , Alexei V. Tkachenko

Disease awareness in infection dynamics can be modeled with adaptive contact networks whose rewiring rules reflect the attempt by susceptibles to avoid infectious contacts. Simulations of this type of models show an active phase with…

Adaptation and Self-Organizing Systems · Physics 2012-12-06 Stefan Wieland , Tomas Aquino , Ana Nunes

Glasses possess complex energy landscapes and exhibit non-equilibrium aging dynamics. Here, we propose a generalized trap model for activated aging based on a key static property of the energy landscape: the distribution of energy barriers.…

Disordered Systems and Neural Networks · Physics 2026-01-22 Bin Li , Deng Pan , Ting Qu , Yuliang Jin

Recent work on particle-based models of tissues has suggested that any finite rate of cell division and cell death is sufficient to fluidize an epithelial tissue. At the same time, experimental evidence has indicated the existence of glassy…

Soft Condensed Matter · Physics 2019-05-07 Michael Czajkowski , Daniel M. Sussman , M. Cristina Marchetti , M. Lisa Manning

We review recent theoretical progress on glassy dynamics, with special emphasis on the importance and universality of the ``aging regime'', which is relevant to many experimental situations. The three main subjects which we address are: (i)…

Disordered Systems and Neural Networks · Physics 2008-02-03 Jean-Philippe Bouchaud , Leticia F. Cugliandolo , Jorge Kurchan , Marc Mezard

We consider a broad class of stochastic imitation dynamics over networks, encompassing several well known learning models such as the replicator dynamics. In the considered models, players have no global information about the game…

Systems and Control · Computer Science 2021-03-02 Lorenzo Zino , Giacomo Como , Fabio Fagnani

We argue that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It…

Populations and Evolution · Quantitative Biology 2008-01-08 E. Ahmed , A. H. Hashish

Cellular automata have been useful artificial models for exploring how relatively simple rules combined with spatial memory can give rise to complex emergent patterns. Moreover, studying the dynamics of how rules emerge under artificial…

Cellular Automata and Lattice Gases · Physics 2014-07-11 Theodore P. Pavlic , Alyssa M. Adams , Paul C. W. Davies , Sara Imari Walker

Many complex systems experience damage accumulation which leads to aging, manifest as an increasing probability of system collapse with time. This naturally raises the question of how to maximize health and longevity in an aging system at…

Populations and Evolution · Quantitative Biology 2020-12-02 Eric D. Sun , Thomas C. T. Michaels , L. Mahadevan

The adaptive and innate branches of the vertebrate immune system work in close collaboration to protect organisms from harmful pathogens. As an organism ages its immune system undergoes immunosenescence, characterized by declined…

Tissues and Organs · Quantitative Biology 2020-08-28 Eric W. Jones , Jiming Sheng , Jean M. Carlson , Shenshen Wang

Transport networks play a key role across four realms of eukaryotic life: slime molds, fungi, plants, and animals. In addition to the developmental algorithms that build them, many also employ adaptive strategies to respond to stimuli,…

Adaptation and Self-Organizing Systems · Physics 2014-06-02 Johannes Gräwer , Carl D. Modes , Marcelo O. Magnasco , Eleni Katifori

The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

Neurons and Cognition · Quantitative Biology 2021-06-04 Udaya B. Rongala , Henrik Jörntell

Widespread interest in non-destructive biomarkers of aging has led to a curse of plenty: a multitude of biological ages that each proffers a 'true' health-adjusted age of an individual. While each measure provides salient information on the…

Quantitative Methods · Quantitative Biology 2024-01-23 Glen Pridham , Andrew D. Rutenberg

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

Statistical Mechanics · Physics 2009-09-30 Zoran Levnajić

We present experiments showing that a granular system of small beads does exhibit ageing properties : its maximum stability angle is measured to increase logarithmically with resting time, i.e. the time elapsed before performing the…

Condensed Matter · Physics 2007-05-23 L. Bocquet , E. Charlaix , S. Ciliberto , J. Crassous

We study the dynamics of gene activities in relatively small size biological networks (up to a few tens of nodes), e.g. the activities of cell-cycle proteins during the mitotic cell-cycle progression. Using the framework of deterministic…

Molecular Networks · Quantitative Biology 2009-11-13 Gautier Stoll , Jacques Rougemont , Felix Naef