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This review focuses on the striking recent progress in solving for hydrophobic interactions between small inert molecules. We discuss several new understandings. Firstly, the _inverse _temperature phenomenology of hydrophobic interactions,…

Chemical Physics · Physics 2016-04-27 L. R. Pratt , Mangesh I. Chaudhari , Susan B. Rempe

Hydrogen bonding is modeled in terms of virtual exchange of protons between water molecules. A simple lattice model is analyzed, using ideas and techniques from the theory of correlated electrons in metals. Reasonable parameters reproduce…

Soft Condensed Matter · Physics 2009-11-11 Daniel W. Hone , P. A. Pincus

The hydrophobic interaction, often combined with the hydrophilic or ionic interactions, makes the behavior of aqueous solutions very rich and plays an important role in biological systems. Theoretical and computer simulation studies haven…

Soft Condensed Matter · Physics 2024-11-05 Hidefumi Naito , Tomonari Sumi , Kenichiro Koga

Molecular dynamic simulations were employed to study a water-like model confined between hydrophobic and hydrophilic plates. The phase behavior of this system is obtained for different distances between the plates and particle-plate…

Soft Condensed Matter · Physics 2015-06-17 Leandro B. Krott , Marcia C. Barbosa

We present a probabilistic approach to water-water hydrogen bonding that allows one to obtain an analytic expression for the number of bonds per water molecule as a function of both its distance to a hydrophobic particle and hydrophobe…

Soft Condensed Matter · Physics 2013-03-20 Yuri S. Djikaev , Eli Ruckenstein

An earlier one-dimensional lattice model of hydrophobic attraction is extended to two and three dimensions and studied by Monte Carlo simulation. The solvent-mediated contribution to the potential of mean force between hydrophobic solute…

Condensed Matter · Physics 2009-10-31 G. T. Barkema , B. Widom

The strength of hydrogen bonding in water is stronger than that of van der waals interaction, therefore water may play an important role in the process of hydrophobic effects. When a hydrophobic solute is dissolved into water, an interface…

Chemical Physics · Physics 2017-03-08 Qiang Sun

On a basis of a two-length scale description of hydrophobic interactions we develop a continuous self-consistent theory of solute-water interactions which allows to determine a hydrophobic layer of a solute molecules of any geometry with…

Soft Condensed Matter · Physics 2007-05-23 G. Sitnikov , S. Nechaev , M. Taran , A. Muryshev

We examine the SPCE and TIP5P water models to study heat capacity effects associated with the hydrophobic hydration and interaction of Xenon particles. We calculate the excess chemical potential for Xenon employing the Widom particle…

Soft Condensed Matter · Physics 2007-05-23 Dietmar Paschek

Many-body interactions can play a relevant role in water properties. Here we study by Monte Carlo simulations a coarse-grained model for bulk water that includes many-body interactions associated to water cooperativity. The model is…

Statistical Mechanics · Physics 2016-10-04 Luis Enrique Coronas , Valentino Bianco , Arne Zantop , Giancarlo Franzese

Thermal behaviors of hydroxypropyl cellulose dilute aqueous solutions with impurities of Group~I alkali metal ions (Li, Na, K, Rb and Cs chlorides) has been studied by means of static and dynamic light scattering measurements. From the…

Soft Condensed Matter · Physics 2025-04-08 Valery I. Kovalchuk

Unstructured proteins can modulate cellular responses to environmental conditions by undergoing coil-globule transitions and phase separation. However, the molecular mechanisms of these phenomena still need to be fully understood. Here, we…

Soft Condensed Matter · Physics 2023-06-28 Bernat Durà Faulí , Valentino Bianco , Giancarlo Franzese

A high level polarizable force field is used to study the temperature dependence of hydrophobic hydration of small-sized molecules from computer simulations. Molecular dynamics (MD) simulations of liquid water at various temperatures form…

Biological Physics · Physics 2007-11-27 R. Mahajan , D. Krazmueller , U. H. E. Hansmann , J. Volkert , S. Hoefinger

The role of solute attractive forces on hydrophobic interactions is studied by coordinated development of theory and simulation results for Ar atoms in water. We present a concise derivation of the local molecular field (LMF) theory for the…

Chemical Physics · Physics 2015-10-28 M. I. Chaudhari , S. B. Rempe , D. Asthagiri , L. Tan , L. R. Pratt

The interactions of a hydrophilic surface with water can significantly influence the characteristics of the liquid water interface. In this manuscript, we explore this influence by studying the molecular structure of liquid water at a…

Soft Condensed Matter · Physics 2022-09-19 Sucheol Shin , Adam P. Willard

We establish the equivalence of a recently introduced discrete model of the hydrophobic interaction, as well as its extension to continuous state variables, with the Ising model in a magnetic field with temperature-dependent strength. In…

Statistical Mechanics · Physics 2016-08-15 G. M. Schütz , I. Ispolatov , G. T. Barkema , B. Widom

The behavior of proteins near interfaces is relevant for biological and medical purposes. Previous results in bulk show that, when the protein concentration increases, the proteins unfold and, at higher concentrations, aggregate. Here, we…

Soft Condensed Matter · Physics 2021-01-19 David March , Valentino Bianco , Giancarlo Franzese

By means of Monte Carlo computer simulations in the isothermal-isobaric ensemble, we investigated the interaction of a hydrophobic ligand with the hydrophobic surfaces of various curvatures (planar, convex and concave). A simple…

Soft Condensed Matter · Physics 2016-03-08 G. Mazovec , M. Lukšič , B. Hribar-Lee

We investigate a lattice-fluid model of water, defined on a 3-dimensional body-centered cubic lattice. Model molecules possess a tetrahedral symmetry, with four equivalent bonding arms. The model is similar to the one proposed by Roberts…

Soft Condensed Matter · Physics 2016-08-31 M. Pretti , C. Buzano

Based on our recent study on physical origin of hydrophobic effects, this is applied to investigate the dependence of hydrophobic interactions on the solute size. As two same hydrophobic solutes are dissolved into water, the hydration free…

Soft Condensed Matter · Physics 2018-03-07 Qiang Sun