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Charge transfer along the base-pair stack in DNA is modeled in terms of thermally-assisted tunneling between adjacent base pairs. Central to our approach is the notion that tunneling between fluctuating pairs is rate-limited by the…

Soft Condensed Matter · Physics 2009-11-07 Maria R. D'Orsogna , Joseph Rudnick

The melting of a homopolymer double-stranded (ds) deoxyribonucleic acid (DNA) in the dilute limit is studied numerically in the presence of an attractive and impenetrable surface on a simple cubic lattice. The two strands of the DNA are…

Soft Condensed Matter · Physics 2023-06-09 Debjyoti Majumdar

We separate double stranded lambda phage DNA by applying a fixed force at a constant temperature ranging from 15C to 50C, and measure the minimum force required to separate the two strands, providing the first experimental determination of…

Soft Condensed Matter · Physics 2009-11-10 C. Danilowicz , Y. Kafri , R. S. Conroy , V. W. Coljee , J. Weeks , M. Prentiss

We have simulated structure and dynamics of water in the grooves of a DNA duplex using moleculear dynamics simulations. We find signatures of a dynamical transition in both translational and orientational dynamics of water molecules in both…

Soft Condensed Matter · Physics 2008-09-23 Debasmita Biswal , Biman Jana , Subrata Pal , Biman Bagchi

We studied how the inhomogeneity of a sequence affects the phase transition that takes place at DNA melting. Unlike previous works, which considered thermodynamic quantities averaged over many different inhomogeneous sequences, we focused…

Biological Physics · Physics 2008-03-07 Sahin Buyukdagli , Marc Joyeux

We use a recently developed coarse-grained model to simulate the overstretching of duplex DNA. Overstretching at 23C occurs at 74 pN in the model, about 6-7 pN higher than the experimental value at equivalent salt conditions. Furthermore,…

Biomolecules · Quantitative Biology 2013-06-25 Flavio Romano , Debayan Chakraborty , Jonathan P. K. Doye , Thomas E. Ouldridge , Ard. A. Louis

A model of dipolar dimer liquid (DDL) on a two-dimensional lattice has been proposed. We found that at high density and low temperature, it has a partially ordered phase which we called glacia phase. The glacia phase transition can be…

Statistical Mechanics · Physics 2019-02-26 Junyi Zhang

We evaluate, by means of molecular dynamics simulations employing a realistic DNA coarse-grained model, the phase behaviour and the structural and dynamic properties of tetravalent DNA nanostars, i.e. nanoconstructs completely made of DNA.…

Soft Condensed Matter · Physics 2014-10-01 Lorenzo Rovigatti , Francesca Bomboi , Francesco Sciortino

The closure dynamics of a pre-equilibrated DNA denaturation bubble is studied using both Brownian dynamics simulations and an analytical approach. The numerical model consists of two semi-flexible interacting single strands (ssDNA) and a…

Soft Condensed Matter · Physics 2012-05-31 Anil Kumar Dasanna , Nicolas Destainville , John Palmeri , Manoel Manghi

Temperature and angular momentum dependence of the quadrupole deformation is studied in the middle of the sd-shell for 28Si and 27Si isotopes using the spherical shell model approach. The shell model calculations have been performed using…

Nuclear Theory · Physics 2010-11-02 P. A. Ganai , J. A. Sheikh , I. Maqbool , R. P. Singh

We employ two Tight-Binding (TB) approaches to study the electronic structure and hole or electron transfer in B-DNA monomer polymers and dimer polymers made up of $N$ monomers (base pairs): (I) at the base-pair level, using the on-site…

We predict a novel temperature-driven phase transition of DNA below the melting transition. The additional, intermediate phase exists for repetitive sequences, when the two strands have different lengths. In this phase, the excess bases of…

Biomolecules · Quantitative Biology 2007-05-23 Richard A. Neher , Ulrich Gerland

The dilatometric investigation in the temperature range of 2-28K shows that a first-order polyamorphous transition occurs in the orientational glasses based on C60 doped with H2, D2 and Xe. A polyamorphous transition was also detected in…

Disordered Systems and Neural Networks · Physics 2009-11-10 A. N. Aleksandrovskii , A. S Bakai , D. Cassidy , A. V. Dolbin , V. B. Esel'son , G. E. Gadd , V. G. Gavrilko , V. G. Manzhelii , S. Moricca , B. Sundqvist

Standard DNA melting curves record the separation of the two strands versus temperature, but they do not provide any information on the location of the opening. We introduce an experimental method which adds a new dimension to the melting…

Statistical Mechanics · Physics 2009-10-25 Santiago Cuesta-Lopez , Dimitar Angelov , Michel Peyrard

Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase. Using Monte Carlo…

Biomolecules · Quantitative Biology 2009-05-04 Hu Chen , Yanhui Liu , Zhen Zhou , Lin Hu , Zhong-Can Ou-Yang , Jie Yan

Motivated by experiments on doped transition metal oxides, this paper considers the interplay of interactions, disorder, kinetic energy and temperature in a simple system. An ensemble of two-site Anderson-Hubbard model systems has already…

Strongly Correlated Electrons · Physics 2015-05-19 R. Wortis , W. A. Atkinson

Kittel's 1D model represents a natural DNA with two strands as a (molecular) zipper, which may separated as the temperature is varied. We define multidimensional version of this model on a Cayley tree and study the set of Gibbs measures. We…

Mathematical Physics · Physics 2023-01-19 U. A. Rozikov

Phase transitions in 1/4-filled quasi-one-dimensional molecular conductors are studied theoretically on the basis of extended Hubbard chains including electron-lattice interactions coupled by interchain Coulomb repulsion. We apply the…

Strongly Correlated Electrons · Physics 2007-05-23 Hitoshi Seo , Yukitoshi Motome , Takeo Kato

When double-stranded DNA molecules are heated, or exposed to denaturing agents, the two strands get separated. The statistical physics of this process has a long history, and is commonly described in term of the Poland-Scheraga (PS) model.…

Biomolecules · Quantitative Biology 2015-09-21 Michaela Reiter-Schad , Erik Werner , Jonas O. Tegenfeldt , Bernhard Mehlig , Tobias Ambjornsson

A unifying theory of the denaturation transition of DNA, driven by temperature T or induced by an external mechanical torque Gamma is presented. Our model couples the hydrogen-bond opening and the untwisting of the helicoidal molecular…

Statistical Mechanics · Physics 2009-10-31 Simona Cocco , Remi Monasson