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The importance of surface tension effects is being recognized in the context of soft composite solids, where it is found to significantly affect the mechanical properties, such as the elastic response to an external stress. It has recently…

Soft Condensed Matter · Physics 2017-02-07 Francesco Mancarella , John S. Wettlaufer

A continuum electromechanical model is proposed to describe the membrane curvature induced by electrostatic interactions in a solvated protein-membrane system. The model couples the macroscopic strain energy of membrane and the…

Quantitative Methods · Quantitative Biology 2015-05-19 Y. C. Zhou , Benzhuo Lu , Alemayehu A. Gorfe

Softer means stickier for solid adhesives, because material compliance facilitates close contact between non-conformal surfaces. Recent discoveries have revealed that soft materials can exhibit a rich array of new physics arising from…

We derive the elastic field generated by multiple small-scaled inclusions distributed in a bounded set of $\mathbb{R}^3$. These inclusions are modeled with moderate values of the Lam\'e coefficients while they have a large relative mass…

Analysis of PDEs · Mathematics 2024-05-10 Durga Prasad Challa , Divya Gangadaraiah , Mourad Sini

Experimentally measuring the elastic properties of thin biological surfaces is non-trivial, particularly when they are curved. One technique that may be used is the indentation of a thin sheet of material by a rigid indenter, whilst…

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

Soft Condensed Matter · Physics 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

We study an elasticity model for compressed protein monolayers or particle rafts at a liquid interface. Based on the microscopic view of hard-core particles with soft shells, a bead-spring model is formulated and analyzed in terms of…

Soft Condensed Matter · Physics 2015-05-12 Sebastian Knoche , Jan Kierfeld

The assembly of curved protein rods on fluid membranes is studied using implicit-solvent meshless membrane simulations. As the rod curvature increases, the rods on a membrane tube assemble along the azimuthal direction first and…

Soft Condensed Matter · Physics 2016-05-18 Hiroshi Noguchi

We derive an effective membrane theory in the thin film limit within a two phase material model for a specimen consisting of an elastic matrix and soft inclusions. The soft inclusions may lead to the formation of cracks within the elastic…

Analysis of PDEs · Mathematics 2022-01-14 Mario Santilli , Bernd Schmidt

In the dilute limit Eshelby's inclusion theory captures the behavior of a wide range of systems and properties. However, because Eshelby's approach neglects interfacial stress, it breaks down in soft materials as the inclusion size…

Soft Condensed Matter · Physics 2016-03-22 Francesco Mancarella , Robert W. Style , John S. Wettlaufer

We investigate membrane-mediated interactions between transmembrane proteins using coarse-grained models. We compare the effective potential of mean force (PMF) between two proteins, which are always aligned parallel to the z-axis of the…

Biological Physics · Physics 2012-04-11 Joerg Neder , Beate West , Peter Nielaba , Friederike Schmid

In linear elastic theory, membrane deformation energy caused by inclusions (e.g., membrane-spanning peptides in lipid bilayers) can be rigorously presented in terms of coupled harmonic oscillators. The general expressions for the…

Biological Physics · Physics 2007-05-23 Yury S. Neustadt , Michael B. Partenskii

Biological membranes are elastic media in which the presence of a transmembrane protein leads to local bilayer deformation. The energetics of deformation allow two membrane proteins in close proximity to influence each other's equilibrium…

Subcellular Processes · Quantitative Biology 2015-06-26 Tristan Ursell , Kerwyn Huang , Eric Peterson , Rob Phillips

In a one-dimensional elastic medium with finite correlation length and purely relaxational dynamics, we calculate the time dependence of the elastic force F(t) exchanged between two active inclusions that trigger an elastic deformation at…

Statistical Mechanics · Physics 2015-06-16 Jean-Baptiste Fournier , Kévin Sin Ronia

The mechanical properties of biological materials are spatially heterogeneous. Typical tissues are made up of a spanning fibrous extracellular matrix in which various inclusions, such as living cells, are embedded. While the influence of…

Soft Condensed Matter · Physics 2025-09-04 Jordan L. Shivers , Jingchen Feng , Fred C. MacKintosh

The hydrodynamic theory of heterogeneous fluid membranes is extended to the case of a membrane adjacent to a solid substrate. We derive the coupling diffusion coefficients of pairs of membrane inclusions in the limit of large separation…

Soft Condensed Matter · Physics 2010-11-10 Naomi Oppenheimer , Haim Diamant

We study the mechanical contact between a deformable body with a wavy surface and a rigid flat taking into account pressurized fluid trapped in the interface. A finite element model is formulated for a general problem of trapped fluid for…

Fluid Dynamics · Physics 2021-03-23 Andrei G. Shvarts , Vladislav A. Yastrebov

We construct a model to explore the hydrodynamic interactions of active inclusions in curved biological membranes. The curved membrane is modelled as a two dimensional layer of highly viscous fluid, surrounded by external solvents of…

Soft Condensed Matter · Physics 2025-06-23 Sarthak Bagaria , Rickmoy Samanta

We consider a family of linearly elastic shells with thickness $2\varepsilon$ (where $\varepsilon$ is a small parameter). The shells are clamped along a portion of their lateral face, all having the same middle surface $S$, and may enter in…

Mathematical Physics · Physics 2016-11-23 Á. Rodríguez-Arós