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We study the stochastic dynamics of evolutionary games, and focus on the so-called `stochastic slowdown' effect, previously observed in (Altrock et. al, 2010) for simple evolutionary dynamics. Slowdown here refers to the fact that a…

Populations and Evolution · Quantitative Biology 2012-07-30 Philipp M. Altrock , Arne Traulsen , Tobias Galla

In this paper, we obtain some stability results of (abstract) dissipative evolution equations with a nonautonomous and nonlinear damping using the exponential stability of the retrograde problem with a linear and autonomous feedback and a…

Analysis of PDEs · Mathematics 2021-10-22 Serge Nicaise

Convolutional architectures have recently been shown to be competitive on many sequence modelling tasks when compared to the de-facto standard of recurrent neural networks (RNNs), while providing computational and modeling advantages due to…

Machine Learning · Computer Science 2019-02-19 Emre Aksan , Otmar Hilliges

Random walks on multidimensional nonlinear landscapes are of interest in many areas of science and engineering. In particular, properties of adaptive trajectories on fitness landscapes determine population fates and thus play a central role…

Populations and Evolution · Quantitative Biology 2014-10-08 Michael Manhart , Alexandre V. Morozov

When mutation rates are low, natural selection remains effective, and increasing the mutation rate can give rise to an increase in adaptation rate. When mutation rates are high to begin with, however, increasing the mutation rate may have a…

Populations and Evolution · Quantitative Biology 2012-11-06 Philip Gerrish , Alexandre Colato , Paul Sniegowski

We employ Monte Carlo simulations to numerically study the temporal evolution and transient oscillations of the population densities, the associated frequency power spectra, and the spatial correlation functions in the (quasi-)steady state…

Populations and Evolution · Quantitative Biology 2015-03-18 Qian He , Mauro Mobilia , Uwe C. Tauber

Thermal evolution of neutron stars is known to depend on the properties of superdense matter in neutron star cores. We suggest a statistical analysis of isolated cooling middle-aged neutron stars and old transiently accreting…

Solar and Stellar Astrophysics · Physics 2015-07-16 M. V. Beznogov , D. G. Yakovlev

The majority of mammalian genomic transcripts do not directly code for proteins and it is currently believed that most of these are not under evolutionary constraint. However given the abundance non-coding RNA (ncRNA) and its strong…

Molecular Networks · Quantitative Biology 2016-08-22 J. M. Deutsch

In this work we employ various methods of analysis (unfolding simulations and comparative analysis of structures and sequences of proteomes of thermophilic organisms) to show that organisms can follow two major strategies of thermophilic…

Biomolecules · Quantitative Biology 2007-05-23 Igor N. Berezovsky , Eugene I. Shakhnovich

In a stochastic process, noise often modifies the picture offered by the mean field dynamics. In particular, when there is an absorbing state, the noise erases a stable fixed point of the mean field equation from the stationary…

Statistical Mechanics · Physics 2018-12-19 JaeJun Lee , Julian Lee

Cells generally change their internal state to adapt to an environmental change, and accordingly evolve in response to the new conditions. This process involves phenotypic changes that occur over several different time scales, ranging from…

Populations and Evolution · Quantitative Biology 2015-02-03 Chikara Furusawa , Kunihiko Kaneko

The stable cooperation ratio of spatial evolutionary games has been widely studied using simulations or approximate analysis methods. However, sometimes such ``stable'' cooperation ratios obtained via approximate methods might not be…

Populations and Evolution · Quantitative Biology 2023-05-01 Jiangjiang Cheng , Wenjun Mei , Wei Su , Ge Chen

Environmental stochasticity is known to be a destabilizing factor, increasing abundance fluctuations and extinction rates of populations. However, the stability of a community may benefit from the differential response of species to…

Populations and Evolution · Quantitative Biology 2016-02-10 Matan Danino , Nadav M. Shnerb , Sandro Azaele , William E. Kunin , David A. Kessler

The broad range of accumulated experimental data on the binding energies for single-particle states in nuclei is examined as a function of the constituent number of neutrons and protons and an unexpectedly simple pattern emerges. The…

Nuclear Theory · Physics 2021-12-14 J. P. Schiffer , B. P. Kay , J. chen

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

We analyze a microscopic RNA model, which includes two widely used models as limiting cases, namely it contains terms for bond as well as for stacking energies. We numerically investigate possible changes in the qualitative and quantitative…

Quantitative Methods · Quantitative Biology 2009-11-10 Bernd Burghardt , Alexander K. Hartmann

RNA function crucially depends on its structure. Thermodynamic models currently used for secondary structure prediction rely on computing the partition function of folding ensembles, and can thus estimate minimum free-energy structures and…

Biomolecules · Quantitative Biology 2022-07-26 Nicola Calonaci , Alisha Jones , Francesca Cuturello , Michael Sattler , Giovanni Bussi

A model of the dynamics of natural rotifer populations is described as a discrete nonlinear map depending on three parameters, which reflect characteristics of the population and environment. Model dynamics and their change by variation of…

Subcellular Processes · Quantitative Biology 2007-05-23 Faina S. Berezovskaya , Georgy P. Karev , Terry W. Snell

In evolutionary dynamics, a key measure of a mutant trait's success is the probability that it takes over the population given some initial mutant-appearance distribution. This "fixation probability" is difficult to compute in general, as…

Populations and Evolution · Quantitative Biology 2022-02-18 Alex McAvoy , Benjamin Allen

We carry out a theoretical study of the vibrational and relaxation properties of naturally-occurring proteins with the purpose of characterizing both the folding and equilibrium thermodynamics. By means of a suitable model we provide a full…

Statistical Mechanics · Physics 2007-05-23 Cristian Micheletti , Gianluca Lattanzi , Amos Maritan