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Sex is considered as an evolutionary paradox, since its evolutionary advantage does not necessarily overcome the two fold cost of sharing half of one's offspring's genome with another member of the population. Here we demonstrate that…

Populations and Evolution · Quantitative Biology 2015-05-13 Alexander Feigel , Avraham Englander , Assaf Engel

This paper studies the mutation-selection balance in three simplified replication models. The first model considers a population of organisms replicating via the production of asexual spores. The second model considers a sexually…

Populations and Evolution · Quantitative Biology 2009-11-13 Emmanuel Tannenbaum

We present a simple model for biological aging. We studied it through computer simulations and we have found this model to reflect some features of real populations.

Condensed Matter · Physics 2009-10-28 Thadeu J. P. Penna

In simulations of sexual reproduction with diploid individuals, we introduce that female haploid gametes recognize one specific allele of the genomes as a marker of the male haploid gametes. They fuse to zygotes preferrably with male…

Populations and Evolution · Quantitative Biology 2009-11-13 S. Cebrat , D. Stauffer

A bit-string model for the evolution of a population of haploid organisms, subject to competition, reproduction with mutation and selection is studied, using mean field theory and Monte Carlo simulations. We show that, depending on…

Statistical Mechanics · Physics 2009-11-07 Kathia M. Fehsenfeld , Ronald Dickman , Americo T. Bernardes

In large asexual populations, multiple beneficial mutations arise in the population, compete, interfere with each other, and accumulate on the same genome, before any of them fix. The resulting dynamics, although studied by many authors, is…

Populations and Evolution · Quantitative Biology 2015-06-11 Daniel S. Fisher

Adaptation often involves the acquisition of a large number of genomic changes which arise as mutations in single individuals. In asexual populations, combinations of mutations can fix only when they arise in the same lineage, but for…

Populations and Evolution · Quantitative Biology 2011-08-18 Richard A. Neher , Boris I. Shraiman , Daniel S. Fisher

We study the evolution of large but finite asexual populations evolving in fitness landscapes in which all mutations are either neutral or strongly deleterious. We demonstrate that despite the absence of higher fitness genotypes, adaptation…

Biological Physics · Physics 2007-05-23 Claus O. Wilke

Much has been debated about the benefit of sexual over asexual reproduction in terms of evolutionary fitness. Here we focus on the advantage that may be brought about by the process of mating, where the choosing of mates contributes to the…

Populations and Evolution · Quantitative Biology 2007-05-23 Wan Ahmad Tajuddin Wan Abdullah

We review models of biological evolution in which the population frequency changes deterministically with time. If the population is self-replicating, although the equations for simple prototypes can be linearised, nonlinear equations arise…

Populations and Evolution · Quantitative Biology 2015-05-27 Kavita Jain , Sarada Seetharaman

Using Monte Carlo model of biological evolution we have discovered that populations can switch between two different strategies of their genomes' evolution; Darwinian purifying selection and complementing the haplotypes. The first one is…

Populations and Evolution · Quantitative Biology 2009-11-13 Marta Zawierta , Wojciech Waga , Dorota Mackiewicz , Przemyslaw Biecek , Stanislaw Cebrat

We have simulated the evolution of sexually reproducing populations composed of individuals represented by diploid genomes. A series of eight bits formed an allele occupying one of 128 loci of one haploid genome (chromosome). The…

Genomics · Quantitative Biology 2009-11-04 S. Cebrat , D. Stauffer , J. S. Sa Martins , S. Moss de Oliveira , P. M. C. de Oliveira

In this article, we investigate the evolution of sexual diploid populations which are hosts for active TE families. Our purpose is to explore the relationship between the environmental change, that influences such population and activity of…

Populations and Evolution · Quantitative Biology 2016-11-16 K. Gogolewski , M. Startek , A. Gambin , A. Le Rouzic

We modify the Penna Model for biological aging, which is based on the mutation-accumulation theory, in order to verify if there would be any evolutionary advantage of triploid over diploid organisms. We show that this is not the case, and…

Statistical Mechanics · Physics 2007-05-23 A. O. Sousa , S. Moss de Oliveira , J. S. Sa Martins

Some practical results are derived for population inference based on a sample, under the two qualitative conditions of 'ignorability' and exchangeability. These are the 'Histogram Theorem', for predicting the outcome of a non-sampled member…

Statistics Theory · Mathematics 2015-11-12 Jonathan Rougier

Using a lattice model based on Monte Carlo simulations, we study the role of the reproduction pattern on the fate of an evolving population. Each individual is under the selection pressure from the environment and random mutations. The…

Statistical Mechanics · Physics 2009-11-10 Mingfeng He , Hongbo Ruan , Changliang Yu , Lei Yao

It has been suggested that the fundamental haploid-diploid cycle of eukaryotic sex exploits a rudimentary form of the Baldwin effect. This paper uses the well-known NKCS model to explore the effects of coevolution upon the behaviour of…

Populations and Evolution · Quantitative Biology 2019-03-19 Larry Bull

Boolean networks have been widely used to explore aspects of gene regulation, traditionally with a single network. A modified form of the model to explore the effects of increasing the number of gene states has also recently been…

Molecular Networks · Quantitative Biology 2024-01-22 Larry Bull

Maintenance of sexual reproduction and genetic recombination imposes physiological costs when compared to parthenogenic reproduction, most prominently: for maintaining the corresponding (molecular) machinery, for finding a mating partner,…

Populations and Evolution · Quantitative Biology 2016-05-24 Dmitri Parkhomchuk , Alice C. McHardy , Alexey Shadrin

We analyse the statistical properties of genealogical trees in a neutral model of a closed population with sexual reproduction and non-overlapping generations. By reconstructing the genealogy of an individual from the population evolution,…

Condensed Matter · Physics 2009-10-31 Bernard Derrida , Susanna C. Manrubia , Damian H. Zanette