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We study counter expressed gene networks constructed from gene-expression data obtained from many types of cancers. The networks are synthesized by connecting vertices belonging to each others' list of K-farthest-neighbors, with K being an…

Molecular Networks · Quantitative Biology 2007-05-23 Himanshu Agrawal

The interplay between topology and dynamics in complex networks is a fundamental but widely unexplored problem. Here, we study this phenomenon on a prototype model in which the network is shaped by a dynamical variable. We couple the…

Statistical Mechanics · Physics 2008-06-13 Diego Garlaschelli , Andrea Capocci , Guido Caldarelli

We investigate a model of evolving random network, introduced by us previously {[}{\it Phys. Rev. Lett.} {\bf 83}, 5587 (1999){]} . The model is a generalization of the Bak-Sneppen model of biological evolution, with the modification that…

Statistical Mechanics · Physics 2009-10-31 Frantisek Slanina , Miroslav Kotrla

In this paper we investigate networks whose evolution is governed by the interaction of a random assembly process and an optimization process. In the first process, new nodes are added one at a time and form connections to randomly selected…

Disordered Systems and Neural Networks · Physics 2011-05-16 Markus Brede

Here we provide a detailed analysis, along with some extensions and additonal investigations, of a recently proposed self-organised model for the evolution of complex networks. Vertices of the network are characterised by a fitness variable…

Physics and Society · Physics 2008-08-29 Guido Caldarelli , Andrea Capocci , Diego Garlaschelli

We construct a gene network based on expression data from DNA microarray experiments, by establishing a link between two genes whenever the Pearson's correlation coefficient between their expression profiles is higher than a certain cutoff.…

Statistical Mechanics · Physics 2007-05-23 P. Provero

Many complex systems--from social and communication networks to biological networks and the Internet--are thought to exhibit scale-free structure. However, prevailing explanations rely on the constant addition of new nodes, an assumption…

Adaptation and Self-Organizing Systems · Physics 2022-11-10 Christopher W. Lynn , Caroline M. Holmes , Stephanie E. Palmer

Systems as diverse as genetic networks or the world wide web are best described as networks with complex topology. A common property of many large networks is that the vertex connectivities follow a scale-free power-law distribution. This…

Disordered Systems and Neural Networks · Physics 2015-06-25 Albert-Laszlo Barabasi , Reka Albert

We review the recent fast progress in statistical physics of evolving networks. Interest has focused mainly on the structural properties of random complex networks in communications, biology, social sciences and economics. A number of giant…

Statistical Mechanics · Physics 2015-06-24 S. N. Dorogovtsev , J. F. F. Mendes

Despite their claimed biological plausibility, most self organizing networks have strict topological constraints and consequently they cannot take into account a wide range of external stimuli. Furthermore their evolution is conditioned by…

General Physics · Physics 2010-04-26 Ignazio Licata , Luigi Lella

Are biological networks different from other large complex networks? Both large biological and non-biological networks exhibit power-law graphs (number of nodes with degree k, N(k) ~ k-b) yet the exponents, b, fall into different ranges.…

Condensed Matter · Physics 2007-05-23 Fan Chung , Linyuan Lu , T. Gregory Dewey , David J. Galas

The structure and the properties of complex networks essentially depend on the way how nodes get connected to each other. We assume here that each node has a feature which attracts the others. We model the situation by assigning two numbers…

Statistical Mechanics · Physics 2009-11-10 Philippe Blanchard , Santo Fortunato , Tyll Krueger

Social networks are organized into communities with dense internal connections, giving rise to high values of the clustering coefficient. In addition, these networks have been observed to be assortative, i.e. highly connected vertices tend…

Physics and Society · Physics 2016-09-08 R. Toivonen , J. -P. Onnela , J. Saramäki , J. Hyvönen , K. Kaski

We propose a method for gene expression based analysis of cancer phenotypes incorporating network biology knowledge through unsupervised construction of computational graphs. The structural construction of the computational graphs is driven…

Molecular Networks · Quantitative Biology 2020-10-02 Paul Scherer , Maja Trȩbacz , Nikola Simidjievski , Zohreh Shams , Helena Andres Terre , Pietro Liò , Mateja Jamnik

The quest to understand structure-function relationships in networks across scientific disciplines has intensified. However, the optimal network architecture remains elusive, particularly for complex information processing. Therefore, we…

Adaptation and Self-Organizing Systems · Physics 2024-03-27 Manish Yadav , Sudeshna Sinha , Merten Stender

We study the organization and dynamics of growing directed networks. These networks are built by adding nodes successively in such a way that each new node has $K$ directed links to the existing ones. The organization of a growing directed…

Statistical Mechanics · Physics 2016-08-31 Baosheng Yuan , Kan Chen , Bing-Hong Wang

Several studies on real complex networks from different fields as biology, economy, or sociology have shown that the degree of nodes (number of edges connected to each node) follows a scale-free power-law distribution like $P(k)\approx…

Biological Physics · Physics 2007-05-23 J. C. Nacher , T. Yamada , S. Goto , M. Kanehisa , T. Akutsu

The organizational development of growing random networks is investigated. These growing networks are built by adding nodes successively and linking each to an earlier node of degree k with attachment probability A_k. When A_k grows slower…

Statistical Mechanics · Physics 2009-10-31 P. L. Krapivsky , S. Redner

We derive the sampling properties of random networks based on weights whose pairwise products parameterize independent Bernoulli trials. This enables an understanding of many degree-based network models, in which the structure of realized…

Statistics Theory · Mathematics 2013-06-07 Sofia C. Olhede , Patrick J. Wolfe

Networks are mathematical structures that are universally used to describe a large variety of complex systems such as the brain or the Internet. Characterizing the geometrical properties of these networks has become increasingly relevant…

Physics and Society · Physics 2015-05-26 Zhihao Wu , Giulia Menichetti , Christoph Rahmede , Ginestra Bianconi
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